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Atomistry » Zinc » PDB 3czn-3d7g » 3d3p » |
Zinc in PDB 3d3p: Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine InhibitorEnzymatic activity of Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
All present enzymatic activity of Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor:
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor, PDB code: 3d3p
was solved by
D.O.Somers,
M.Neu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3d3p:
The structure of Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
(pdb code 3d3p). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor, PDB code: 3d3p: Zinc binding site 1 out of 1 in 3d3pGo back to Zinc Binding Sites List in 3d3p
Zinc binding site 1 out
of 1 in the Crystal Structure of PDE4B Catalytic Domain in Complex with A Pyrazolopyridine Inhibitor
Mono view Stereo pair view
Reference:
J.N.Hamblin,
T.D.Angell,
S.P.Ballantine,
C.M.Cook,
A.W.Cooper,
J.Dawson,
C.J.Delves,
P.S.Jones,
M.Lindvall,
F.S.Lucas,
C.J.Mitchell,
M.Y.Neu,
L.E.Ranshaw,
Y.E.Solanke,
D.O.Somers,
J.O.Wiseman.
Pyrazolopyridines As A Novel Structural Class of Potent and Selective PDE4 Inhibitors. Bioorg.Med.Chem.Lett. V. 18 4237 2008.
Page generated: Wed Dec 16 04:12:00 2020
ISSN: ISSN 0960-894X PubMed: 18539455 DOI: 10.1016/J.BMCL.2008.05.052 |
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