Zinc in PDB 3cxl: Crystal Structure of Human Chimerin 1 (CHN1)

The structure of Crystal Structure of Human Chimerin 1 (CHN1), PDB code: 3cxl was solved by L.Shen, M.Buck, Y.Tong, W.Tempel, F.Mackenzie, C.H.Arrowsmith, A.M.Edwards, C.Bountra, M.Wilkstrom, A.Bochkarev, H.Park, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.51 / 2.60
Space group	P 62
Cell size a, b, c (Å), α, β, γ (°)	152.187, 152.187, 69.529, 90.00, 90.00, 120.00
R / Rfree (%)	26.6 / 30

The binding sites of Zinc atom in the Crystal Structure of Human Chimerin 1 (CHN1) (pdb code 3cxl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Chimerin 1 (CHN1), PDB code: 3cxl:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Chimerin 1 (CHN1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Chimerin 1 (CHN1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn500 b:61.7 occ:1.00 ND1 A:HIS206 2.1 58.4 1.0 SG A:CYS239 2.3 58.4 1.0 SG A:CYS236 2.3 58.9 1.0 SG A:CYS255 2.3 57.2 1.0 CE1 A:HIS206 2.8 58.0 1.0 CB A:CYS239 3.2 58.4 1.0 CG A:HIS206 3.2 57.5 1.0 CB A:CYS236 3.4 58.9 1.0 CB A:CYS255 3.4 56.7 1.0 N A:CYS239 3.6 58.2 1.0 CB A:HIS206 3.8 57.4 1.0 NE2 A:HIS206 3.9 58.8 1.0 CA A:CYS239 4.0 58.1 1.0 CA A:CYS255 4.0 56.5 1.0 CA A:HIS206 4.1 57.3 1.0 CD2 A:HIS206 4.2 58.0 1.0 CB A:ASP238 4.3 58.2 1.0 C A:ASP238 4.6 58.3 1.0 N A:ASN207 4.7 56.6 1.0 CA A:CYS236 4.8 59.0 1.0 C A:CYS239 4.8 57.8 1.0 N A:GLY240 4.8 57.5 1.0 N A:LYS256 4.8 56.5 1.0 C A:CYS255 4.8 56.6 1.0 CA A:ASP238 4.8 58.2 1.0 N A:ASP238 4.9 58.4 1.0 C A:HIS206 4.9 57.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Chimerin 1 (CHN1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Chimerin 1 (CHN1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:51.3 occ:1.00 ND1 A:HIS244 2.1 53.0 1.0 SG A:CYS219 2.3 54.6 1.0 SG A:CYS222 2.3 52.0 1.0 SG A:CYS247 2.3 54.4 1.0 CE1 A:HIS244 2.9 53.5 1.0 CG A:HIS244 3.2 52.4 1.0 CB A:CYS219 3.2 53.5 1.0 CB A:CYS222 3.3 52.6 1.0 CB A:CYS247 3.3 54.9 1.0 CB A:HIS244 3.7 53.8 1.0 N A:CYS222 3.9 52.8 1.0 CE A:MET137 3.9 57.6 1.0 N A:HIS244 4.1 54.0 1.0 NE2 A:HIS244 4.1 53.7 1.0 CA A:CYS222 4.2 52.5 1.0 CD2 A:HIS244 4.2 53.1 1.0 CA A:HIS244 4.5 53.8 1.0 CB A:TYR221 4.6 52.8 1.0 CA A:CYS247 4.7 55.5 1.0 CA A:CYS219 4.7 53.7 1.0 C A:CYS222 4.8 52.4 1.0 CD2 A:TYR221 4.8 51.9 1.0 C A:TYR221 4.9 52.7 1.0 N A:ALA223 5.0 52.7 1.0

L.Shen, M.Buck, Y.Tong, W.Tempel, F.Mackenzie, C.H.Arrowsmith, A.M.Edwards, C.Bountra, M.Wilkstrom, A.Bochkarev, H.Park. Crystal Structure of Human Chimerin 1 (CHN1). To Be Published.