Zinc in PDB 3cx3: Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein

The structure of Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein, PDB code: 3cx3 was solved by E.Loisel, C.Durmort, L.Jacquamet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.90 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.760, 63.260, 151.660, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 29.5

The structure of Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Zinc atom in the Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein (pdb code 3cx3). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein, PDB code: 3cx3:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn314 b:36.9 occ:1.00 NE2 A:HIS71 2.0 30.5 1.0 NE2 A:HIS147 2.0 22.8 1.0 OE2 A:GLU286 2.1 42.4 1.0 NE2 A:HIS211 2.1 25.9 1.0 CE1 A:HIS147 2.8 26.2 1.0 CD A:GLU286 2.8 43.1 1.0 CE1 A:HIS71 2.9 28.0 1.0 CD2 A:HIS71 3.0 32.0 1.0 CE1 A:HIS211 3.0 25.7 1.0 CD2 A:HIS211 3.1 23.6 1.0 OE1 A:GLU286 3.2 42.2 1.0 CD2 A:HIS147 3.2 25.1 1.0 O A:ILE231 3.5 40.1 1.0 ND1 A:HIS71 4.0 31.2 1.0 CG A:GLU286 4.0 44.8 1.0 ND1 A:HIS147 4.0 22.2 1.0 CG A:HIS71 4.1 35.1 1.0 ND1 A:HIS211 4.2 23.9 1.0 CG A:HIS211 4.2 27.5 1.0 CG A:HIS147 4.2 26.2 1.0 CB A:ALA213 4.3 34.1 1.0 C A:ILE231 4.7 39.7 1.0 CD A:PRO233 4.8 44.2 1.0 CH2 A:TRP149 4.9 27.0 1.0 CA A:ALA213 5.0 33.6 1.0 CZ2 A:TRP149 5.0 26.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure Analysis of the Streptococcus Pneumoniae Adcaii Protein within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn312 b:37.3 occ:1.00 OE2 B:GLU286 1.7 43.0 1.0 NE2 B:HIS71 1.9 40.2 1.0 CE1 B:HIS147 2.0 29.9 1.0 NE2 B:HIS211 2.4 34.9 1.0 CD B:GLU286 2.7 41.7 1.0 NE2 B:HIS147 2.8 29.1 1.0 CE1 B:HIS71 2.9 39.2 1.0 CD2 B:HIS71 2.9 39.3 1.0 OE1 B:GLU286 3.1 39.8 1.0 ND1 B:HIS147 3.2 29.8 1.0 CD2 B:HIS211 3.2 34.1 1.0 CE1 B:HIS211 3.4 32.0 1.0 O B:ILE231 3.6 33.8 1.0 ND1 B:HIS71 4.0 38.9 1.0 CG B:HIS71 4.0 41.4 1.0 CG B:GLU286 4.0 44.6 1.0 CD2 B:HIS147 4.0 30.1 1.0 CG B:HIS147 4.2 30.5 1.0 CB B:ALA213 4.3 33.5 1.0 CG B:HIS211 4.4 34.4 1.0 ND1 B:HIS211 4.5 33.1 1.0 CA B:ALA213 4.8 33.5 1.0 CD B:PRO233 4.8 42.3 1.0 CZ2 B:TRP149 4.8 32.4 1.0 C B:ILE231 4.8 35.2 1.0 CH2 B:TRP149 4.9 34.2 1.0 O B:THR212 5.0 32.6 1.0

E.Loisel, L.Jacquamet, L.Serre, C.Bauvois, J.L.Ferrer, T.Vernet, A.M.Di Guilmi, C.Durmort. Adcaii, A New Pneumococcal Zn-Binding Protein Homologous with Abc Transporters: Biochemical and Structural Analysis. J.Mol.Biol. V. 381 594 2008.
ISSN: ISSN 0022-2836
PubMed: 18632116
DOI: 10.1016/J.JMB.2008.05.068