|
Atomistry » Zinc » PDB 3avr-3b6n » 3b3n | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3avr-3b6n » 3b3n » |
Zinc in PDB 3b3n: Structure of Neuronal Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Cis-4'-[(6"-Aminopyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}Ethane-1,2-DiamineEnzymatic activity of Structure of Neuronal Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Cis-4'-[(6"-Aminopyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}Ethane-1,2-Diamine
All present enzymatic activity of Structure of Neuronal Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Cis-4'-[(6"-Aminopyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}Ethane-1,2-Diamine:
1.14.13.39; Protein crystallography data
The structure of Structure of Neuronal Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Cis-4'-[(6"-Aminopyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}Ethane-1,2-Diamine, PDB code: 3b3n
was solved by
J.Igarashi,
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3b3n:
The structure of Structure of Neuronal Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Cis-4'-[(6"-Aminopyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}Ethane-1,2-Diamine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Neuronal Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Cis-4'-[(6"-Aminopyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}Ethane-1,2-Diamine
(pdb code 3b3n). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Neuronal Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Cis-4'-[(6"-Aminopyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}Ethane-1,2-Diamine, PDB code: 3b3n: Zinc binding site 1 out of 1 in 3b3nGo back to Zinc Binding Sites List in 3b3n
Zinc binding site 1 out
of 1 in the Structure of Neuronal Nos Heme Domain in Complex with A Inhibitor (+-)-N1-{Cis-4'-[(6"-Aminopyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}Ethane-1,2-Diamine
Mono view Stereo pair view
Reference:
H.Ji,
B.Z.Stanton,
J.Igarashi,
H.Li,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Minimal Pharmacophoric Elements and Fragment Hopping, An Approach Directed at Molecular Diversity and Isozyme Selectivity. Design of Selective Neuronal Nitric Oxide Synthase Inhibitors. J.Am.Chem.Soc. V. 130 3900 2008.
Page generated: Wed Dec 16 04:08:21 2020
ISSN: ISSN 0002-7863 PubMed: 18321097 DOI: 10.1021/JA0772041 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |