Zinc in PDB 2zo4: Crystal Structure of Metallo-Beta-Lactamase Family Protein TTHA1429 From Thermus Thermophilus HB8

The structure of Crystal Structure of Metallo-Beta-Lactamase Family Protein TTHA1429 From Thermus Thermophilus HB8, PDB code: 2zo4 was solved by A.Yamamura, K.Nagata, Y.Agari, A.Ebihara, N.Nakagawa, S.Yokoyama, S.Kuramitsu, M.Tanokura, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.286, 62.885, 87.425, 90.00, 90.00, 90.00
R / Rfree (%)	19.8 / 25.7

The binding sites of Zinc atom in the Crystal Structure of Metallo-Beta-Lactamase Family Protein TTHA1429 From Thermus Thermophilus HB8 (pdb code 2zo4). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Metallo-Beta-Lactamase Family Protein TTHA1429 From Thermus Thermophilus HB8, PDB code: 2zo4:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Metallo-Beta-Lactamase Family Protein TTHA1429 From Thermus Thermophilus HB8


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Metallo-Beta-Lactamase Family Protein TTHA1429 From Thermus Thermophilus HB8 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn318 b:14.6 occ:1.00 O A:HOH320 2.0 8.0 1.0 NE2 A:HIS171 2.1 11.2 1.0 ND1 A:HIS72 2.2 10.5 1.0 NE2 A:HIS70 2.2 9.3 1.0 OD2 A:ASP190 2.6 11.9 1.0 CD2 A:HIS171 3.0 9.9 1.0 CD2 A:HIS70 3.0 8.0 1.0 CE1 A:HIS171 3.1 10.6 1.0 CE1 A:HIS72 3.2 11.1 1.0 CG A:HIS72 3.2 10.1 1.0 ZN A:ZN319 3.3 14.2 1.0 CE1 A:HIS70 3.3 8.3 1.0 CB A:HIS72 3.5 10.0 1.0 CG A:ASP190 3.5 11.5 1.0 CB A:ASP190 3.8 11.2 1.0 NE2 A:HIS75 4.1 9.9 1.0 CD2 A:HIS75 4.1 9.5 1.0 CG A:HIS171 4.2 10.0 1.0 ND1 A:HIS171 4.2 10.6 1.0 CG A:HIS70 4.2 8.3 1.0 NE2 A:HIS72 4.3 10.7 1.0 CD2 A:HIS72 4.3 10.8 1.0 ND1 A:HIS70 4.4 7.8 1.0 OD1 A:ASP74 4.5 12.5 1.0 OD1 A:ASP190 4.6 11.3 1.0 OD2 A:ASP74 4.7 12.3 1.0 CA A:HIS72 5.0 9.8 1.0 O A:HOH527 5.0 58.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Metallo-Beta-Lactamase Family Protein TTHA1429 From Thermus Thermophilus HB8


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Metallo-Beta-Lactamase Family Protein TTHA1429 From Thermus Thermophilus HB8 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn319 b:14.2 occ:1.00 O A:HOH320 2.0 8.0 1.0 NE2 A:HIS75 2.1 9.9 1.0 OD2 A:ASP190 2.1 11.9 1.0 NE2 A:HIS233 2.1 13.8 1.0 OD2 A:ASP74 2.3 12.3 1.0 CD2 A:HIS75 2.9 9.5 1.0 CG A:ASP190 3.0 11.5 1.0 CD2 A:HIS233 3.0 13.4 1.0 CE1 A:HIS233 3.1 13.8 1.0 CE1 A:HIS75 3.2 8.8 1.0 OD1 A:ASP190 3.2 11.3 1.0 ZN A:ZN318 3.3 14.6 1.0 CG A:ASP74 3.3 12.3 1.0 OD1 A:ASP74 3.7 12.5 1.0 NE2 A:HIS70 4.1 9.3 1.0 CG A:HIS75 4.1 10.0 1.0 ND1 A:HIS233 4.2 13.5 1.0 CG A:HIS233 4.2 13.3 1.0 ND1 A:HIS75 4.2 8.9 1.0 CE1 A:HIS70 4.3 8.3 1.0 CB A:ASP190 4.4 11.2 1.0 O A:HOH455 4.5 28.1 1.0 CB A:ASP74 4.6 11.2 1.0 CG2 A:VAL22 4.7 15.1 1.0 NE2 A:HIS171 4.8 11.2 1.0

A.Yamamura, J.Ohtsuka, K.Kubota, Y.Agari, A.Ebihara, N.Nakagawa, K.Nagata, M.Tanokura. Crystal Structure of TTHA1429, A Novel Metallo-Beta-Lactamase Superfamily Protein From Thermus Thermophilus HB8. Proteins V. 73 1053 2008.
ISSN: ISSN 0887-3585
PubMed: 18767153
DOI: 10.1002/PROT.22215