Zinc in PDB 2zky: Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
Enzymatic activity of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
All present enzymatic activity of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A:
1.15.1.1;
Protein crystallography data
The structure of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A, PDB code: 2zky
was solved by
S.Yoshikawa,
M.Kukimoto-Niino,
K.Ito,
M.Shirouzu,
M.Urushitani,
R.Takahashi,
S.Yokoyama,
Riken Structural Genomics/Proteomicsinitiative (Rsgi),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
49.93 /
2.40
|
|
Space group
|
C 2 2 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
165.238,
204.509,
144.819,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
18.9 /
23.5
|
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
(pdb code 2zky). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 10 binding sites of Zinc where determined in the
Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A, PDB code: 2zky:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 1 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn601
b:33.9
occ:1.00
|
OD1
|
A:ASP83
|
2.0
|
26.1
|
1.0
|
|
ND1
|
A:HIS63
|
2.1
|
35.4
|
1.0
|
|
ND1
|
A:HIS71
|
2.2
|
46.4
|
1.0
|
|
ND1
|
A:HIS80
|
2.2
|
27.8
|
1.0
|
|
CG
|
A:ASP83
|
2.8
|
32.4
|
1.0
|
|
OD2
|
A:ASP83
|
2.9
|
27.5
|
1.0
|
|
CE1
|
A:HIS71
|
3.0
|
39.6
|
1.0
|
|
CG
|
A:HIS63
|
3.1
|
36.1
|
1.0
|
|
CG
|
A:HIS80
|
3.1
|
32.4
|
1.0
|
|
CE1
|
A:HIS63
|
3.2
|
30.4
|
1.0
|
|
CE1
|
A:HIS80
|
3.2
|
28.5
|
1.0
|
|
CG
|
A:HIS71
|
3.3
|
48.5
|
1.0
|
|
CB
|
A:HIS63
|
3.3
|
26.6
|
1.0
|
|
CB
|
A:HIS80
|
3.3
|
31.7
|
1.0
|
|
CB
|
A:HIS71
|
3.7
|
34.6
|
1.0
|
|
CA
|
A:HIS71
|
3.9
|
39.5
|
1.0
|
|
O
|
A:LYS136
|
4.0
|
57.3
|
1.0
|
|
NE2
|
A:HIS71
|
4.2
|
46.4
|
1.0
|
|
CB
|
A:ASP83
|
4.2
|
18.4
|
1.0
|
|
CD2
|
A:HIS63
|
4.2
|
41.0
|
1.0
|
|
CD2
|
A:HIS80
|
4.2
|
28.7
|
1.0
|
|
NE2
|
A:HIS63
|
4.2
|
39.7
|
1.0
|
|
NE2
|
A:HIS80
|
4.3
|
35.8
|
1.0
|
|
CD2
|
A:HIS71
|
4.3
|
46.7
|
1.0
|
|
N
|
A:GLY72
|
4.6
|
33.5
|
1.0
|
|
CA
|
A:HIS80
|
4.7
|
39.0
|
1.0
|
|
CA
|
A:ASP83
|
4.7
|
26.6
|
1.0
|
|
N
|
A:HIS80
|
4.8
|
37.0
|
1.0
|
|
C
|
A:HIS71
|
4.8
|
32.2
|
1.0
|
|
CA
|
A:HIS63
|
4.9
|
30.6
|
1.0
|
|
C
|
A:LYS136
|
5.0
|
59.0
|
1.0
|
|
N
|
A:HIS71
|
5.0
|
37.5
|
1.0
|
|
Zinc binding site 2 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 2 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn602
b:23.4
occ:1.00
|
OD1
|
B:ASP83
|
1.9
|
29.0
|
1.0
|
|
ND1
|
B:HIS63
|
2.0
|
21.7
|
1.0
|
|
ND1
|
B:HIS80
|
2.0
|
20.0
|
1.0
|
|
ND1
|
B:HIS71
|
2.0
|
21.0
|
1.0
|
|
CG
|
B:ASP83
|
2.7
|
28.1
|
1.0
|
|
OD2
|
B:ASP83
|
2.8
|
31.0
|
1.0
|
|
CE1
|
B:HIS71
|
2.8
|
18.4
|
1.0
|
|
CE1
|
B:HIS80
|
2.9
|
20.6
|
1.0
|
|
CE1
|
B:HIS63
|
2.9
|
9.9
|
1.0
|
|
CG
|
B:HIS63
|
3.0
|
25.8
|
1.0
|
|
CG
|
B:HIS80
|
3.0
|
22.3
|
1.0
|
|
CG
|
B:HIS71
|
3.1
|
31.0
|
1.0
|
|
CB
|
B:HIS63
|
3.4
|
19.0
|
1.0
|
|
CB
|
B:HIS80
|
3.5
|
9.3
|
1.0
|
|
CB
|
B:HIS71
|
3.6
|
17.2
|
1.0
|
|
O
|
B:LYS136
|
3.9
|
29.7
|
1.0
|
|
CA
|
B:HIS71
|
3.9
|
19.3
|
1.0
|
|
NE2
|
B:HIS80
|
4.0
|
23.9
|
1.0
|
|
NE2
|
B:HIS63
|
4.0
|
17.8
|
1.0
|
|
NE2
|
B:HIS71
|
4.0
|
24.2
|
1.0
|
|
CD2
|
B:HIS80
|
4.0
|
21.0
|
1.0
|
|
CD2
|
B:HIS63
|
4.1
|
17.1
|
1.0
|
|
CB
|
B:ASP83
|
4.1
|
25.2
|
1.0
|
|
CD2
|
B:HIS71
|
4.2
|
19.4
|
1.0
|
|
CA
|
B:ASP83
|
4.7
|
18.1
|
1.0
|
|
N
|
B:HIS80
|
4.7
|
20.7
|
1.0
|
|
N
|
B:GLY72
|
4.7
|
21.5
|
1.0
|
|
CA
|
B:HIS80
|
4.7
|
14.6
|
1.0
|
|
O
|
B:HOH635
|
4.8
|
29.1
|
1.0
|
|
CD2
|
B:HIS46
|
4.8
|
17.8
|
1.0
|
|
C
|
B:HIS71
|
4.9
|
22.0
|
1.0
|
|
N
|
B:ASP83
|
4.9
|
19.8
|
1.0
|
|
CA
|
B:HIS63
|
4.9
|
25.1
|
1.0
|
|
C
|
B:LYS136
|
5.0
|
29.0
|
1.0
|
|
N
|
B:HIS71
|
5.0
|
21.2
|
1.0
|
|
Zinc binding site 3 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 3 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn603
b:35.5
occ:1.00
|
ND1
|
C:HIS80
|
1.9
|
22.9
|
1.0
|
|
OD1
|
C:ASP83
|
1.9
|
39.2
|
1.0
|
|
ND1
|
C:HIS71
|
2.2
|
33.5
|
1.0
|
|
ND1
|
C:HIS63
|
2.2
|
49.4
|
1.0
|
|
CG
|
C:ASP83
|
2.7
|
46.6
|
1.0
|
|
CE1
|
C:HIS80
|
2.8
|
28.6
|
1.0
|
|
CG
|
C:HIS80
|
2.8
|
35.6
|
1.0
|
|
OD2
|
C:ASP83
|
2.9
|
38.3
|
1.0
|
|
CE1
|
C:HIS71
|
3.1
|
40.0
|
1.0
|
|
CG
|
C:HIS63
|
3.2
|
39.8
|
1.0
|
|
CG
|
C:HIS71
|
3.2
|
29.7
|
1.0
|
|
CE1
|
C:HIS63
|
3.2
|
36.3
|
1.0
|
|
CB
|
C:HIS80
|
3.3
|
34.9
|
1.0
|
|
CB
|
C:HIS63
|
3.4
|
37.2
|
1.0
|
|
CB
|
C:HIS71
|
3.5
|
32.8
|
1.0
|
|
O
|
C:LYS136
|
3.8
|
52.1
|
1.0
|
|
NE2
|
C:HIS80
|
3.8
|
35.8
|
1.0
|
|
CA
|
C:HIS71
|
3.9
|
38.0
|
1.0
|
|
CD2
|
C:HIS80
|
3.9
|
29.1
|
1.0
|
|
CB
|
C:ASP83
|
4.1
|
31.4
|
1.0
|
|
NE2
|
C:HIS71
|
4.2
|
38.0
|
1.0
|
|
CD2
|
C:HIS71
|
4.3
|
30.4
|
1.0
|
|
NE2
|
C:HIS63
|
4.3
|
46.0
|
1.0
|
|
CD2
|
C:HIS63
|
4.3
|
49.1
|
1.0
|
|
CA
|
C:HIS80
|
4.6
|
39.5
|
1.0
|
|
CA
|
C:ASP83
|
4.6
|
34.4
|
1.0
|
|
N
|
C:HIS80
|
4.7
|
48.4
|
1.0
|
|
N
|
C:GLY72
|
4.7
|
42.1
|
1.0
|
|
O
|
C:HOH627
|
4.8
|
38.5
|
1.0
|
|
C
|
C:LYS136
|
4.8
|
53.8
|
1.0
|
|
N
|
C:ASP83
|
4.8
|
36.2
|
1.0
|
|
N
|
C:HIS71
|
4.9
|
42.0
|
1.0
|
|
C
|
C:HIS71
|
4.9
|
39.7
|
1.0
|
|
CA
|
C:HIS63
|
5.0
|
35.6
|
1.0
|
|
Zinc binding site 4 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 4 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn604
b:20.6
occ:1.00
|
OD1
|
D:ASP83
|
1.9
|
20.4
|
1.0
|
|
ND1
|
D:HIS63
|
1.9
|
26.3
|
1.0
|
|
ND1
|
D:HIS71
|
2.0
|
20.4
|
1.0
|
|
ND1
|
D:HIS80
|
2.0
|
27.5
|
1.0
|
|
CG
|
D:ASP83
|
2.7
|
18.9
|
1.0
|
|
OD2
|
D:ASP83
|
2.8
|
17.3
|
1.0
|
|
CE1
|
D:HIS71
|
2.8
|
23.7
|
1.0
|
|
CE1
|
D:HIS63
|
2.9
|
20.1
|
1.0
|
|
CG
|
D:HIS63
|
3.0
|
27.5
|
1.0
|
|
CE1
|
D:HIS80
|
3.0
|
17.7
|
1.0
|
|
CG
|
D:HIS80
|
3.0
|
27.6
|
1.0
|
|
CG
|
D:HIS71
|
3.2
|
22.6
|
1.0
|
|
CB
|
D:HIS63
|
3.4
|
24.8
|
1.0
|
|
CB
|
D:HIS80
|
3.4
|
28.4
|
1.0
|
|
CB
|
D:HIS71
|
3.6
|
24.6
|
1.0
|
|
O
|
D:LYS136
|
3.8
|
20.6
|
1.0
|
|
CA
|
D:HIS71
|
3.9
|
24.1
|
1.0
|
|
NE2
|
D:HIS71
|
4.0
|
24.6
|
1.0
|
|
NE2
|
D:HIS63
|
4.0
|
21.7
|
1.0
|
|
CD2
|
D:HIS63
|
4.1
|
23.6
|
1.0
|
|
NE2
|
D:HIS80
|
4.1
|
21.4
|
1.0
|
|
CB
|
D:ASP83
|
4.1
|
19.1
|
1.0
|
|
CD2
|
D:HIS80
|
4.1
|
28.2
|
1.0
|
|
CD2
|
D:HIS71
|
4.2
|
18.4
|
1.0
|
|
N
|
D:GLY72
|
4.6
|
21.6
|
1.0
|
|
CA
|
D:ASP83
|
4.6
|
19.1
|
1.0
|
|
CA
|
D:HIS80
|
4.6
|
24.6
|
1.0
|
|
N
|
D:HIS80
|
4.7
|
25.5
|
1.0
|
|
O
|
D:HOH628
|
4.8
|
26.2
|
1.0
|
|
C
|
D:HIS71
|
4.8
|
24.8
|
1.0
|
|
C
|
D:LYS136
|
4.9
|
26.3
|
1.0
|
|
N
|
D:ASP83
|
4.9
|
21.4
|
1.0
|
|
CD2
|
D:HIS46
|
4.9
|
18.0
|
1.0
|
|
CA
|
D:HIS63
|
4.9
|
20.9
|
1.0
|
|
N
|
D:HIS71
|
5.0
|
29.3
|
1.0
|
|
Zinc binding site 5 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 5 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn605
b:28.2
occ:1.00
|
OD1
|
E:ASP83
|
1.9
|
19.3
|
1.0
|
|
ND1
|
E:HIS63
|
2.0
|
30.9
|
1.0
|
|
ND1
|
E:HIS80
|
2.0
|
21.4
|
1.0
|
|
ND1
|
E:HIS71
|
2.1
|
35.9
|
1.0
|
|
CG
|
E:ASP83
|
2.7
|
25.2
|
1.0
|
|
OD2
|
E:ASP83
|
2.8
|
27.0
|
1.0
|
|
CE1
|
E:HIS80
|
2.9
|
29.4
|
1.0
|
|
CG
|
E:HIS63
|
3.0
|
38.8
|
1.0
|
|
CE1
|
E:HIS63
|
3.0
|
30.8
|
1.0
|
|
CG
|
E:HIS80
|
3.0
|
28.2
|
1.0
|
|
CE1
|
E:HIS71
|
3.0
|
33.6
|
1.0
|
|
CG
|
E:HIS71
|
3.2
|
33.4
|
1.0
|
|
CB
|
E:HIS63
|
3.3
|
21.9
|
1.0
|
|
CB
|
E:HIS80
|
3.5
|
25.2
|
1.0
|
|
CB
|
E:HIS71
|
3.6
|
25.8
|
1.0
|
|
O
|
E:LYS136
|
3.6
|
47.1
|
1.0
|
|
CA
|
E:HIS71
|
4.0
|
28.4
|
1.0
|
|
NE2
|
E:HIS80
|
4.0
|
25.7
|
1.0
|
|
NE2
|
E:HIS63
|
4.1
|
35.5
|
1.0
|
|
CD2
|
E:HIS80
|
4.1
|
30.5
|
1.0
|
|
CD2
|
E:HIS63
|
4.1
|
33.0
|
1.0
|
|
CB
|
E:ASP83
|
4.1
|
20.8
|
1.0
|
|
NE2
|
E:HIS71
|
4.2
|
32.9
|
1.0
|
|
CD2
|
E:HIS71
|
4.3
|
34.6
|
1.0
|
|
C
|
E:LYS136
|
4.7
|
44.2
|
1.0
|
|
CA
|
E:ASP83
|
4.7
|
20.3
|
1.0
|
|
CA
|
E:HIS80
|
4.7
|
29.8
|
1.0
|
|
N
|
E:GLY72
|
4.7
|
30.3
|
1.0
|
|
N
|
E:HIS80
|
4.7
|
37.2
|
1.0
|
|
O
|
E:HOH650
|
4.9
|
31.9
|
1.0
|
|
CA
|
E:HIS63
|
4.9
|
29.4
|
1.0
|
|
N
|
E:HIS71
|
4.9
|
25.1
|
1.0
|
|
C
|
E:HIS71
|
4.9
|
33.1
|
1.0
|
|
Zinc binding site 6 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 6 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Zn606
b:20.4
occ:1.00
|
OD1
|
F:ASP83
|
1.9
|
9.6
|
1.0
|
|
ND1
|
F:HIS63
|
1.9
|
27.0
|
1.0
|
|
ND1
|
F:HIS80
|
2.1
|
19.7
|
1.0
|
|
ND1
|
F:HIS71
|
2.1
|
20.9
|
1.0
|
|
CG
|
F:ASP83
|
2.7
|
26.7
|
1.0
|
|
CE1
|
F:HIS63
|
2.9
|
24.0
|
1.0
|
|
OD2
|
F:ASP83
|
3.0
|
18.1
|
1.0
|
|
CG
|
F:HIS63
|
3.0
|
23.6
|
1.0
|
|
CE1
|
F:HIS80
|
3.0
|
23.0
|
1.0
|
|
CE1
|
F:HIS71
|
3.0
|
23.1
|
1.0
|
|
CG
|
F:HIS80
|
3.1
|
21.1
|
1.0
|
|
CG
|
F:HIS71
|
3.2
|
25.1
|
1.0
|
|
CB
|
F:HIS63
|
3.4
|
12.6
|
1.0
|
|
CB
|
F:HIS80
|
3.4
|
23.5
|
1.0
|
|
CB
|
F:HIS71
|
3.5
|
13.9
|
1.0
|
|
O
|
F:LYS136
|
3.8
|
34.7
|
1.0
|
|
CA
|
F:HIS71
|
3.9
|
23.6
|
1.0
|
|
NE2
|
F:HIS63
|
4.0
|
26.8
|
1.0
|
|
CD2
|
F:HIS63
|
4.1
|
18.1
|
1.0
|
|
NE2
|
F:HIS80
|
4.1
|
22.3
|
1.0
|
|
CB
|
F:ASP83
|
4.2
|
14.7
|
1.0
|
|
CD2
|
F:HIS80
|
4.2
|
16.2
|
1.0
|
|
NE2
|
F:HIS71
|
4.2
|
23.2
|
1.0
|
|
CD2
|
F:HIS71
|
4.3
|
17.1
|
1.0
|
|
N
|
F:GLY72
|
4.7
|
28.4
|
1.0
|
|
CA
|
F:HIS80
|
4.7
|
20.7
|
1.0
|
|
N
|
F:HIS80
|
4.7
|
26.9
|
1.0
|
|
CA
|
F:ASP83
|
4.7
|
20.3
|
1.0
|
|
C
|
F:LYS136
|
4.8
|
32.5
|
1.0
|
|
C
|
F:HIS71
|
4.8
|
22.8
|
1.0
|
|
O
|
F:HOH614
|
4.9
|
22.1
|
1.0
|
|
N
|
F:HIS71
|
4.9
|
16.7
|
1.0
|
|
CD2
|
F:HIS46
|
4.9
|
20.6
|
1.0
|
|
N
|
F:ASP83
|
4.9
|
23.1
|
1.0
|
|
CA
|
F:HIS63
|
5.0
|
22.6
|
1.0
|
|
Zinc binding site 7 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 7 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn607
b:52.8
occ:1.00
|
OD1
|
G:ASP83
|
1.9
|
46.0
|
1.0
|
|
ND1
|
G:HIS71
|
2.2
|
70.5
|
1.0
|
|
ND1
|
G:HIS80
|
2.2
|
42.4
|
1.0
|
|
ND1
|
G:HIS63
|
2.3
|
64.6
|
1.0
|
|
CG
|
G:ASP83
|
2.7
|
52.1
|
1.0
|
|
OD2
|
G:ASP83
|
2.8
|
52.0
|
1.0
|
|
CE1
|
G:HIS71
|
3.0
|
68.7
|
1.0
|
|
CE1
|
G:HIS80
|
3.1
|
42.2
|
1.0
|
|
CG
|
G:HIS80
|
3.1
|
43.1
|
1.0
|
|
CG
|
G:HIS63
|
3.2
|
61.6
|
1.0
|
|
CG
|
G:HIS71
|
3.2
|
71.0
|
1.0
|
|
CE1
|
G:HIS63
|
3.3
|
68.2
|
1.0
|
|
CB
|
G:HIS63
|
3.4
|
53.0
|
1.0
|
|
CB
|
G:HIS80
|
3.5
|
52.0
|
1.0
|
|
O
|
G:LYS136
|
3.5
|
78.9
|
1.0
|
|
CB
|
G:HIS71
|
3.6
|
68.4
|
1.0
|
|
CA
|
G:HIS71
|
3.9
|
69.3
|
1.0
|
|
CB
|
G:ASP83
|
4.1
|
50.1
|
1.0
|
|
NE2
|
G:HIS71
|
4.2
|
71.2
|
1.0
|
|
NE2
|
G:HIS80
|
4.2
|
44.3
|
1.0
|
|
CD2
|
G:HIS80
|
4.2
|
42.5
|
1.0
|
|
CD2
|
G:HIS71
|
4.3
|
72.5
|
1.0
|
|
CD2
|
G:HIS63
|
4.3
|
70.8
|
1.0
|
|
NE2
|
G:HIS63
|
4.3
|
74.9
|
1.0
|
|
C
|
G:LYS136
|
4.7
|
76.2
|
1.0
|
|
CA
|
G:ASP83
|
4.7
|
54.0
|
1.0
|
|
N
|
G:GLY72
|
4.7
|
69.7
|
1.0
|
|
CA
|
G:HIS80
|
4.8
|
53.3
|
1.0
|
|
N
|
G:ASP83
|
4.8
|
52.0
|
1.0
|
|
N
|
G:HIS80
|
4.8
|
63.8
|
1.0
|
|
CD2
|
G:HIS46
|
4.8
|
55.1
|
1.0
|
|
CA
|
G:HIS63
|
4.9
|
52.0
|
1.0
|
|
C
|
G:HIS71
|
4.9
|
70.6
|
1.0
|
|
N
|
G:HIS71
|
4.9
|
71.0
|
1.0
|
|
Zinc binding site 8 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 8 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Zn608
b:32.2
occ:1.00
|
OD1
|
H:ASP83
|
1.9
|
26.5
|
1.0
|
|
ND1
|
H:HIS80
|
1.9
|
35.5
|
1.0
|
|
ND1
|
H:HIS71
|
2.0
|
20.1
|
1.0
|
|
ND1
|
H:HIS63
|
2.1
|
35.1
|
1.0
|
|
CG
|
H:ASP83
|
2.6
|
35.7
|
1.0
|
|
CE1
|
H:HIS80
|
2.8
|
36.0
|
1.0
|
|
OD2
|
H:ASP83
|
2.8
|
31.6
|
1.0
|
|
CE1
|
H:HIS71
|
2.8
|
28.5
|
1.0
|
|
CG
|
H:HIS80
|
2.9
|
35.8
|
1.0
|
|
CG
|
H:HIS63
|
3.1
|
27.2
|
1.0
|
|
CG
|
H:HIS71
|
3.1
|
33.2
|
1.0
|
|
CE1
|
H:HIS63
|
3.1
|
22.9
|
1.0
|
|
CB
|
H:HIS63
|
3.3
|
28.6
|
1.0
|
|
CB
|
H:HIS80
|
3.4
|
35.1
|
1.0
|
|
CB
|
H:HIS71
|
3.6
|
23.2
|
1.0
|
|
NE2
|
H:HIS80
|
3.8
|
35.2
|
1.0
|
|
CA
|
H:HIS71
|
3.9
|
30.7
|
1.0
|
|
O
|
H:LYS136
|
3.9
|
36.2
|
1.0
|
|
CD2
|
H:HIS80
|
3.9
|
38.3
|
1.0
|
|
NE2
|
H:HIS71
|
4.0
|
32.3
|
1.0
|
|
CB
|
H:ASP83
|
4.1
|
34.4
|
1.0
|
|
CD2
|
H:HIS71
|
4.1
|
26.5
|
1.0
|
|
CD2
|
H:HIS63
|
4.2
|
26.6
|
1.0
|
|
NE2
|
H:HIS63
|
4.2
|
37.3
|
1.0
|
|
CA
|
H:ASP83
|
4.6
|
32.5
|
1.0
|
|
N
|
H:GLY72
|
4.6
|
30.9
|
1.0
|
|
N
|
H:HIS80
|
4.6
|
33.7
|
1.0
|
|
CA
|
H:HIS80
|
4.6
|
30.3
|
1.0
|
|
N
|
H:ASP83
|
4.8
|
25.1
|
1.0
|
|
C
|
H:HIS71
|
4.8
|
32.7
|
1.0
|
|
CA
|
H:HIS63
|
4.9
|
31.9
|
1.0
|
|
C
|
H:LYS136
|
4.9
|
34.8
|
1.0
|
|
N
|
H:HIS71
|
4.9
|
37.1
|
1.0
|
|
CD2
|
H:HIS46
|
5.0
|
26.5
|
1.0
|
|
O
|
H:HOH614
|
5.0
|
27.1
|
1.0
|
|
Zinc binding site 9 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 9 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn609
b:47.6
occ:1.00
|
OD1
|
I:ASP83
|
2.0
|
55.8
|
1.0
|
|
ND1
|
I:HIS63
|
2.1
|
39.5
|
1.0
|
|
ND1
|
I:HIS80
|
2.1
|
55.8
|
1.0
|
|
ND1
|
I:HIS71
|
2.2
|
85.7
|
1.0
|
|
CG
|
I:ASP83
|
2.6
|
53.4
|
1.0
|
|
OD2
|
I:ASP83
|
2.7
|
50.7
|
1.0
|
|
CE1
|
I:HIS80
|
3.0
|
56.5
|
1.0
|
|
CE1
|
I:HIS63
|
3.0
|
45.5
|
1.0
|
|
CE1
|
I:HIS71
|
3.1
|
88.4
|
1.0
|
|
CG
|
I:HIS80
|
3.1
|
53.5
|
1.0
|
|
CG
|
I:HIS63
|
3.1
|
46.9
|
1.0
|
|
CG
|
I:HIS71
|
3.3
|
84.0
|
1.0
|
|
CB
|
I:HIS63
|
3.5
|
48.9
|
1.0
|
|
CB
|
I:HIS80
|
3.5
|
52.3
|
1.0
|
|
CB
|
I:HIS71
|
3.7
|
77.0
|
1.0
|
|
O
|
I:LYS136
|
3.9
|
73.0
|
1.0
|
|
CB
|
I:ASP83
|
4.0
|
51.7
|
1.0
|
|
CA
|
I:HIS71
|
4.0
|
74.4
|
1.0
|
|
NE2
|
I:HIS80
|
4.0
|
55.6
|
1.0
|
|
CD2
|
I:HIS80
|
4.1
|
50.3
|
1.0
|
|
NE2
|
I:HIS63
|
4.2
|
46.1
|
1.0
|
|
NE2
|
I:HIS71
|
4.2
|
84.8
|
1.0
|
|
CD2
|
I:HIS63
|
4.2
|
48.1
|
1.0
|
|
CD2
|
I:HIS71
|
4.3
|
86.2
|
1.0
|
|
CA
|
I:ASP83
|
4.6
|
49.0
|
1.0
|
|
N
|
I:GLY72
|
4.6
|
70.0
|
1.0
|
|
CA
|
I:HIS80
|
4.8
|
58.1
|
1.0
|
|
N
|
I:HIS80
|
4.8
|
60.9
|
1.0
|
|
CD2
|
I:HIS46
|
4.8
|
42.9
|
1.0
|
|
C
|
I:LYS136
|
4.9
|
76.2
|
1.0
|
|
C
|
I:HIS71
|
4.9
|
73.7
|
1.0
|
|
N
|
I:ASP83
|
4.9
|
51.4
|
1.0
|
|
Zinc binding site 10 out
of 10 in 2zky
Go back to
Zinc Binding Sites List in 2zky
Zinc binding site 10 out
of 10 in the Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn610
b:32.9
occ:1.00
|
OD1
|
J:ASP83
|
1.9
|
38.6
|
1.0
|
|
ND1
|
J:HIS80
|
2.0
|
36.8
|
1.0
|
|
ND1
|
J:HIS71
|
2.1
|
37.4
|
1.0
|
|
ND1
|
J:HIS63
|
2.2
|
27.6
|
1.0
|
|
CG
|
J:ASP83
|
2.7
|
42.5
|
1.0
|
|
OD2
|
J:ASP83
|
2.8
|
30.4
|
1.0
|
|
CE1
|
J:HIS71
|
2.9
|
40.7
|
1.0
|
|
CE1
|
J:HIS80
|
2.9
|
22.7
|
1.0
|
|
CG
|
J:HIS80
|
3.0
|
31.8
|
1.0
|
|
CG
|
J:HIS63
|
3.1
|
31.4
|
1.0
|
|
CE1
|
J:HIS63
|
3.2
|
32.1
|
1.0
|
|
CG
|
J:HIS71
|
3.2
|
33.2
|
1.0
|
|
CB
|
J:HIS63
|
3.3
|
30.7
|
1.0
|
|
CB
|
J:HIS80
|
3.5
|
36.5
|
1.0
|
|
CB
|
J:HIS71
|
3.7
|
28.8
|
1.0
|
|
O
|
J:LYS136
|
3.7
|
38.4
|
1.0
|
|
NE2
|
J:HIS80
|
4.0
|
28.3
|
1.0
|
|
NE2
|
J:HIS71
|
4.1
|
40.0
|
1.0
|
|
CB
|
J:ASP83
|
4.1
|
37.4
|
1.0
|
|
CD2
|
J:HIS80
|
4.1
|
30.8
|
1.0
|
|
CA
|
J:HIS71
|
4.1
|
37.1
|
1.0
|
|
CD2
|
J:HIS71
|
4.2
|
37.8
|
1.0
|
|
CD2
|
J:HIS63
|
4.3
|
33.9
|
1.0
|
|
NE2
|
J:HIS63
|
4.3
|
29.4
|
1.0
|
|
CA
|
J:ASP83
|
4.6
|
37.5
|
1.0
|
|
CA
|
J:HIS80
|
4.7
|
35.3
|
1.0
|
|
N
|
J:HIS80
|
4.7
|
40.2
|
1.0
|
|
O
|
J:HOH619
|
4.8
|
36.4
|
1.0
|
|
N
|
J:GLY72
|
4.8
|
41.0
|
1.0
|
|
C
|
J:LYS136
|
4.8
|
42.7
|
1.0
|
|
CA
|
J:HIS63
|
4.9
|
37.6
|
1.0
|
|
CD2
|
J:HIS46
|
4.9
|
41.6
|
1.0
|
|
N
|
J:ASP83
|
4.9
|
33.0
|
1.0
|
|
C
|
J:HIS71
|
5.0
|
39.9
|
1.0
|
|
Reference:
S.Yoshikawa,
M.Kukimoto-Niino,
K.Ito,
M.Shirouzu,
M.Urushitani,
R.Takahashi,
S.Yokoyama.
Crystal Structure of Human Cu-Zn Superoxide Dismutase Mutant G93A To Be Published.
Page generated: Thu Oct 24 10:48:47 2024
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