Zinc in PDB 2z94: Complex Structure of Sars-Cov 3C-Like Protease with Tdt

The structure of Complex Structure of Sars-Cov 3C-Like Protease with Tdt, PDB code: 2z94 was solved by C.C.Lee, A.H.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.78
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	108.511, 81.548, 53.334, 90.00, 105.13, 90.00
R / Rfree (%)	19.1 / 22.4

The binding sites of Zinc atom in the Complex Structure of Sars-Cov 3C-Like Protease with Tdt (pdb code 2z94). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Complex Structure of Sars-Cov 3C-Like Protease with Tdt, PDB code: 2z94:

Zinc binding site 1 out of 1 in the Complex Structure of Sars-Cov 3C-Like Protease with Tdt


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Complex Structure of Sars-Cov 3C-Like Protease with Tdt within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn901 b:34.6 occ:1.00 NE2 A:HIS41 2.1 29.0 1.0 S17 A:TLD902 2.3 39.5 1.0 S15 A:TLD902 2.3 40.6 1.0 SG A:CYS145 2.3 31.5 1.0 CD2 A:HIS41 3.0 31.2 1.0 CE1 A:HIS41 3.1 32.7 1.0 C3 A:TLD902 3.2 41.7 1.0 C2 A:TLD902 3.2 41.9 1.0 CB A:CYS145 3.2 27.5 1.0 O A:HOH1139 3.6 51.4 1.0 CG A:HIS41 4.2 30.9 1.0 ND1 A:HIS41 4.2 32.7 1.0 O A:HIS164 4.2 27.2 1.0 O A:HOH1351 4.3 65.7 1.0 CD2 A:LEU27 4.4 27.5 1.0 O A:HOH1134 4.5 39.5 1.0 CA A:CYS145 4.6 26.2 1.0 C4 A:TLD902 4.6 43.7 1.0 C1 A:TLD902 4.6 44.4 1.0 O A:HOH1136 4.9 51.8 1.0 O A:HOH1352 5.0 60.9 1.0

C.C.Lee, C.J.Kuo, M.F.Hsu, P.H.Liang, J.M.Fang, J.J.Shie, A.H.Wang. Structural Basis of Mercury- and Zinc-Conjugated Complexes As Sars-Cov 3C-Like Protease Inhibitors Febs Lett. V. 581 5454 2007.
ISSN: ISSN 0014-5793
PubMed: 17981158
DOI: 10.1016/J.FEBSLET.2007.10.048