Atomistry » Zinc » PDB 2x8z-2xjl » 2xcm
Atomistry »
  Zinc »
    PDB 2x8z-2xjl »
      2xcm »

Zinc in PDB 2xcm: Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain

Protein crystallography data

The structure of Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain, PDB code: 2xcm was solved by M.Zhang, L.H.Pearl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.78 / 2.20
Space group P 32
Cell size a, b, c (Å), α, β, γ (°) 88.890, 88.890, 117.820, 90.00, 90.00, 120.00
R / Rfree (%) 19.8 / 24.2

Other elements in 2xcm:

The structure of Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain (pdb code 2xcm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain, PDB code: 2xcm:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 2xcm

Go back to Zinc Binding Sites List in 2xcm
Zinc binding site 1 out of 4 in the Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn1222

b:20.8
occ:1.00
SG E:CYS178 2.3 21.5 1.0
SG E:CYS159 2.3 20.2 1.0
ND1 E:HIS218 2.3 21.9 1.0
SG E:CYS164 2.4 21.6 1.0
CB E:CYS159 3.1 23.4 1.0
CB E:CYS178 3.1 21.1 1.0
CB E:CYS164 3.2 25.4 1.0
CE1 E:HIS218 3.2 21.4 1.0
CG E:HIS218 3.4 22.1 1.0
CA E:HIS218 3.7 19.2 1.0
CB E:HIS218 3.7 20.6 1.0
CA E:CYS178 4.0 21.0 1.0
ND2 E:ASN161 4.1 22.1 1.0
O E:HOH2016 4.3 25.7 1.0
NE2 E:HIS218 4.4 22.9 1.0
CD2 E:HIS218 4.5 16.0 1.0
CB E:ASN161 4.5 22.3 1.0
N E:HIS218 4.6 24.7 1.0
CA E:CYS159 4.6 24.5 1.0
CA E:CYS164 4.7 28.5 1.0
N E:SER219 4.7 24.6 1.0
CG E:ASN161 4.8 24.9 1.0
C E:HIS218 4.8 24.1 1.0
C E:CYS178 4.8 22.6 1.0

Zinc binding site 2 out of 4 in 2xcm

Go back to Zinc Binding Sites List in 2xcm
Zinc binding site 2 out of 4 in the Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn1223

b:22.7
occ:1.00
ND1 E:HIS181 2.2 19.9 1.0
SG E:CYS196 2.3 21.9 1.0
SG E:CYS197 2.4 22.9 1.0
SG E:CYS213 2.4 24.2 1.0
CE1 E:HIS181 3.0 22.6 1.0
CB E:CYS213 3.2 22.4 1.0
CG E:HIS181 3.3 23.8 1.0
N E:CYS197 3.3 25.3 1.0
CB E:CYS197 3.4 24.4 1.0
CB E:CYS196 3.4 23.0 1.0
CB E:HIS181 3.7 22.6 1.0
CA E:HIS181 3.9 24.2 1.0
CB E:TRP194 3.9 20.4 1.0
CA E:CYS197 4.0 23.8 1.0
C E:CYS196 4.0 27.1 1.0
CA E:CYS196 4.2 24.9 1.0
NE2 E:HIS181 4.2 24.2 1.0
N E:CYS213 4.2 24.2 1.0
CD2 E:HIS181 4.3 22.9 1.0
CA E:CYS213 4.4 23.1 1.0
CD E:PRO182 4.4 19.4 1.0
CG E:TRP194 4.4 22.2 1.0
N E:CYS196 4.5 23.9 1.0
C E:HIS181 4.8 22.0 1.0
N E:PRO182 4.8 20.9 1.0
CD2 E:TRP194 4.9 22.1 1.0

Zinc binding site 3 out of 4 in 2xcm

Go back to Zinc Binding Sites List in 2xcm
Zinc binding site 3 out of 4 in the Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn1222

b:21.2
occ:1.00
SG F:CYS178 2.3 22.1 1.0
ND1 F:HIS218 2.3 23.9 1.0
SG F:CYS159 2.3 21.6 1.0
SG F:CYS164 2.4 23.5 1.0
CB F:CYS178 3.1 19.8 1.0
CB F:CYS159 3.1 22.4 1.0
CE1 F:HIS218 3.2 23.0 1.0
CB F:CYS164 3.2 25.6 1.0
CG F:HIS218 3.4 22.8 1.0
CA F:HIS218 3.7 20.4 1.0
CB F:HIS218 3.7 22.4 1.0
CA F:CYS178 4.0 20.3 1.0
ND2 F:ASN161 4.2 18.9 1.0
NE2 F:HIS218 4.3 22.3 1.0
CB F:ASN161 4.4 22.8 1.0
CD2 F:HIS218 4.5 18.1 1.0
O F:HOH2015 4.5 27.3 1.0
N F:HIS218 4.6 24.9 1.0
CA F:CYS159 4.6 25.1 1.0
CA F:CYS164 4.7 29.5 1.0
CG F:ASN161 4.7 25.6 1.0
N F:SER219 4.8 25.8 1.0
C F:HIS218 4.8 25.1 1.0
C F:CYS178 4.9 20.9 1.0

Zinc binding site 4 out of 4 in 2xcm

Go back to Zinc Binding Sites List in 2xcm
Zinc binding site 4 out of 4 in the Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Complex of HSP90 N-Terminal, SGT1 Cs and RAR1 CHORD2 Domain within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn1223

b:22.5
occ:1.00
ND1 F:HIS181 2.2 20.8 1.0
SG F:CYS196 2.4 21.8 1.0
SG F:CYS197 2.4 22.2 1.0
SG F:CYS213 2.4 25.3 1.0
CE1 F:HIS181 3.0 23.6 1.0
CB F:CYS213 3.3 25.9 1.0
N F:CYS197 3.3 24.8 1.0
CG F:HIS181 3.3 24.2 1.0
CB F:CYS197 3.3 23.2 1.0
CB F:CYS196 3.5 23.0 1.0
CB F:HIS181 3.8 23.6 1.0
CB F:TRP194 3.9 18.1 1.0
CA F:HIS181 3.9 24.9 1.0
CA F:CYS197 3.9 24.2 1.0
C F:CYS196 4.0 24.8 1.0
NE2 F:HIS181 4.2 25.1 1.0
CA F:CYS196 4.2 22.1 1.0
N F:CYS213 4.2 27.2 1.0
CD2 F:HIS181 4.4 23.8 1.0
CA F:CYS213 4.4 25.8 1.0
CG F:TRP194 4.4 21.0 1.0
CD F:PRO182 4.5 20.2 1.0
N F:CYS196 4.6 22.4 1.0
C F:HIS181 4.8 23.0 1.0
N F:PRO182 4.9 20.4 1.0
O F:HOH2030 4.9 28.9 1.0
CD2 F:TRP194 4.9 20.3 1.0
O F:CYS196 4.9 25.6 1.0

Reference:

M.Zhang, Y.Kadota, C.Prodromou, K.Shirasu, L.H.Pearl. Structural Basis For Assembly of HSP90-SGT1-Chord Protein Complexes: Implications For Chaperoning of Nlr Innate Immunity Receptors Mol.Cell V. 39 269 2010.
ISSN: ISSN 1097-2765
PubMed: 20670895
DOI: 10.1016/J.MOLCEL.2010.05.010
Page generated: Wed Dec 16 03:59:44 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy