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Zinc in PDB 2x7t: Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors.
Enzymatic activity of Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors.
All present enzymatic activity of Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors.:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors., PDB code: 2x7t
was solved by
G.E.Cozier,
M.P.Leese,
M.D.Lloyd,
M.D.Baker,
N.Thiyagarajan,
K.R.Acharya,
B.V.L.Potter,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 22.99 / 1.89 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.256, 40.832, 72.697, 90.00, 104.49, 90.00 |
| R / Rfree (%) | 21.1 / 24.8 |
Zinc Binding Sites:
The binding sites of Zinc atom in the Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors.
(pdb code 2x7t). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors., PDB code: 2x7t:
Jump to Zinc binding site number: 1; 2;
In total 2 binding sites of Zinc where determined in the Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors., PDB code: 2x7t:
Jump to Zinc binding site number: 1; 2;
Zinc binding site 1 out of 2 in 2x7t
Go back to
Zinc Binding Sites List in 2x7t
Zinc binding site 1 out
of 2 in the Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors. within 5.0Å range:
|
Zinc binding site 2 out of 2 in 2x7t
Go back to
Zinc Binding Sites List in 2x7t
Zinc binding site 2 out
of 2 in the Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors. within 5.0Å range:
|
Reference:
G.E.Cozier,
M.P.Leese,
M.D.Lloyd,
M.D.Baker,
N.Thiyagarajan,
K.R.Acharya,
B.V.L.Potter.
Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal A Second Binding Site For Steroidal and Non-Steroidal Inhibitors. Biochemistry V. 49 3464 2010.
ISSN: ISSN 0006-2960
PubMed: 20297840
DOI: 10.1021/BI902178W
Page generated: Thu Oct 17 05:11:12 2024
ISSN: ISSN 0006-2960
PubMed: 20297840
DOI: 10.1021/BI902178W
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