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Atomistry » Zinc » PDB 2wwo-2x8y » 2x0w » |
Zinc in PDB 2x0w: Structure of the P53 Core Domain Mutant Y220C Bound to 5,6-Dimethoxy- 2-MethylbenzothiazoleProtein crystallography data
The structure of Structure of the P53 Core Domain Mutant Y220C Bound to 5,6-Dimethoxy- 2-Methylbenzothiazole, PDB code: 2x0w
was solved by
J.L.Kaar,
N.Basse,
A.C.Joerger,
A.R.Fersht,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of the P53 Core Domain Mutant Y220C Bound to 5,6-Dimethoxy- 2-Methylbenzothiazole
(pdb code 2x0w). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the P53 Core Domain Mutant Y220C Bound to 5,6-Dimethoxy- 2-Methylbenzothiazole, PDB code: 2x0w: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 2x0wGo back to Zinc Binding Sites List in 2x0w
Zinc binding site 1 out
of 2 in the Structure of the P53 Core Domain Mutant Y220C Bound to 5,6-Dimethoxy- 2-Methylbenzothiazole
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 2x0wGo back to Zinc Binding Sites List in 2x0w
Zinc binding site 2 out
of 2 in the Structure of the P53 Core Domain Mutant Y220C Bound to 5,6-Dimethoxy- 2-Methylbenzothiazole
Mono view Stereo pair view
Reference:
N.Basse,
J.L.Kaar,
G.Settanni,
A.C.Joerger,
T.J.Rutherford,
A.R.Fersht.
Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chem.Biol. V. 17 46 2010.
Page generated: Wed Dec 16 03:58:56 2020
ISSN: ISSN 1074-5521 PubMed: 20142040 DOI: 10.1016/J.CHEMBIOL.2009.12.011 |
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