Zinc in PDB 2vm5: Human BIR2 Domain of Baculoviral Inhibitor of Apoptosis Repeat-Containing 1 (BIRC1)

The structure of Human BIR2 Domain of Baculoviral Inhibitor of Apoptosis Repeat-Containing 1 (BIRC1), PDB code: 2vm5 was solved by M.D.Herman, M.Welin, C.H.Arrowsmith, H.Berglund, R.D.Busam, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, I.Johansson, A.Kallas, T.Karlberg, T.Kotenyova, L.Lehtio, M.Moche, M.E.Nilsson, T.Nyman, C.Persson, J.Sagemark, L.Svensson, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, P.Nordlund, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.500, 43.100, 57.000, 90.00, 90.00, 90.00
R / Rfree (%)	17.8 / 22

The binding sites of Zinc atom in the Human BIR2 Domain of Baculoviral Inhibitor of Apoptosis Repeat-Containing 1 (BIRC1) (pdb code 2vm5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human BIR2 Domain of Baculoviral Inhibitor of Apoptosis Repeat-Containing 1 (BIRC1), PDB code: 2vm5:

Zinc binding site 1 out of 1 in the Human BIR2 Domain of Baculoviral Inhibitor of Apoptosis Repeat-Containing 1 (BIRC1)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human BIR2 Domain of Baculoviral Inhibitor of Apoptosis Repeat-Containing 1 (BIRC1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1245 b:11.1 occ:1.00 NE2 A:HIS217 2.2 6.8 1.0 SG A:CYS200 2.3 9.9 1.0 SG A:CYS224 2.3 10.2 1.0 SG A:CYS197 2.4 11.2 1.0 CE1 A:HIS217 3.0 8.9 1.0 CB A:CYS197 3.1 8.7 1.0 CB A:CYS224 3.1 9.0 1.0 CB A:CYS200 3.2 10.2 1.0 CD2 A:HIS217 3.3 8.0 1.0 N A:CYS200 3.7 10.8 1.0 CA A:CYS200 4.0 11.1 1.0 ND1 A:HIS217 4.2 9.3 1.0 CG A:HIS217 4.3 8.9 1.0 CA A:CYS224 4.4 9.7 1.0 CA A:CYS197 4.6 9.1 1.0 CB A:SER199 4.6 12.1 1.0 CB A:PHE221 4.7 9.5 1.0 C A:SER199 4.8 11.8 1.0 C A:CYS200 4.8 11.6 1.0 CG A:LEU227 4.9 12.3 1.0 CB A:PHE226 4.9 12.5 1.0 CD2 A:PHE221 5.0 10.7 1.0 CD2 A:PHE226 5.0 14.1 1.0

M.D.Herman, M.Moche, S.Flodin, M.Welin, L.Tresaugues, I.Johansson, M.E.Nilsson, P.Nordlund, T.Nyman. Structures of Bir Domains From Human Naip and CIAP2. Acta Crystallogr.,Sect.F V. 65 1091 2009.
ISSN: ISSN 1744-3091
PubMed: 19923725
DOI: 10.1107/S1744309109038597