Zinc in PDB 2ro1: uc(Nmr) Solution Structures of Human KAP1 Phd Finger-Bromodomain

The binding sites of Zinc atom in the uc(Nmr) Solution Structures of Human KAP1 Phd Finger-Bromodomain (pdb code 2ro1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the uc(Nmr) Solution Structures of Human KAP1 Phd Finger-Bromodomain, PDB code: 2ro1:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the uc(Nmr) Solution Structures of Human KAP1 Phd Finger-Bromodomain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Solution Structures of Human KAP1 Phd Finger-Bromodomain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:0.0 occ:1.00 ND1 A:HIS648 2.0 0.0 1.0 SG A:CYS628 2.2 0.0 1.0 SG A:CYS651 2.2 0.0 1.0 SG A:CYS631 2.2 0.0 1.0 HB2 A:HIS648 2.6 0.0 1.0 HB3 A:CYS628 3.0 0.0 1.0 HB2 A:CYS631 3.0 0.0 1.0 CE1 A:HIS648 3.0 0.0 1.0 CG A:HIS648 3.0 0.0 1.0 CB A:CYS628 3.1 0.0 1.0 H A:CYS631 3.2 0.0 1.0 HB2 A:CYS651 3.2 0.0 1.0 HE1 A:HIS648 3.2 0.0 1.0 CB A:CYS631 3.3 0.0 1.0 CB A:CYS651 3.3 0.0 1.0 CB A:HIS648 3.3 0.0 1.0 HB2 A:CYS628 3.4 0.0 1.0 HB A:VAL630 3.4 0.0 1.0 H A:HIS648 3.5 0.0 1.0 HB3 A:CYS651 3.5 0.0 1.0 HB3 A:HIS648 3.9 0.0 1.0 N A:CYS631 4.0 0.0 1.0 HB3 A:CYS631 4.0 0.0 1.0 NE2 A:HIS648 4.1 0.0 1.0 CD2 A:HIS648 4.1 0.0 1.0 CA A:CYS631 4.2 0.0 1.0 N A:HIS648 4.3 0.0 1.0 O A:CYS628 4.3 0.0 1.0 HG13 A:VAL630 4.4 0.0 1.0 CA A:HIS648 4.4 0.0 1.0 CB A:VAL630 4.4 0.0 1.0 H A:CYS651 4.5 0.0 1.0 CA A:CYS628 4.6 0.0 1.0 HG23 A:VAL630 4.6 0.0 1.0 CA A:CYS651 4.6 0.0 1.0 HA A:CYS631 4.7 0.0 1.0 HB2 A:LYS633 4.9 0.0 1.0 OD2 A:ASP650 4.9 0.0 1.0 C A:CYS628 4.9 0.0 1.0 HA A:PHE647 4.9 0.0 1.0 CG1 A:VAL630 4.9 0.0 1.0 N A:CYS651 4.9 0.0 1.0 H A:GLN632 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the uc(Nmr) Solution Structures of Human KAP1 Phd Finger-Bromodomain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Solution Structures of Human KAP1 Phd Finger-Bromodomain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:0.0 occ:1.00 SG A:CYS640 2.2 0.0 1.0 SG A:CYS666 2.3 0.0 1.0 SG A:CYS643 2.3 0.0 1.0 SG A:CYS669 2.3 0.0 1.0 HB2 A:PHE645 2.7 0.0 1.0 HB2 A:CYS669 3.1 0.0 1.0 HB2 A:CYS666 3.1 0.0 1.0 HB2 A:CYS640 3.2 0.0 1.0 CB A:CYS640 3.2 0.0 1.0 HB3 A:CYS643 3.3 0.0 1.0 CB A:CYS669 3.3 0.0 1.0 CB A:CYS666 3.3 0.0 1.0 CB A:CYS643 3.4 0.0 1.0 HB3 A:CYS640 3.5 0.0 1.0 H A:CYS643 3.6 0.0 1.0 CB A:PHE645 3.6 0.0 1.0 HB3 A:CYS669 3.7 0.0 1.0 HB3 A:PHE645 3.9 0.0 1.0 H A:PHE645 4.0 0.0 1.0 N A:CYS643 4.0 0.0 1.0 N A:CYS666 4.0 0.0 1.0 CG A:PHE645 4.0 0.0 1.0 H A:CYS666 4.0 0.0 1.0 HB2 A:GLN642 4.1 0.0 1.0 CA A:CYS643 4.1 0.0 1.0 HA A:SER665 4.1 0.0 1.0 HB3 A:CYS666 4.1 0.0 1.0 C A:SER665 4.2 0.0 1.0 HB2 A:CYS643 4.2 0.0 1.0 HB3 A:SER665 4.3 0.0 1.0 CA A:CYS666 4.3 0.0 1.0 HG22 A:VAL810 4.3 0.0 1.0 HD13 A:LEU668 4.4 0.0 1.0 CD2 A:PHE645 4.4 0.0 1.0 HD2 A:PHE645 4.4 0.0 1.0 C A:CYS643 4.5 0.0 1.0 O A:SER665 4.6 0.0 1.0 CD1 A:PHE645 4.6 0.0 1.0 CA A:SER665 4.6 0.0 1.0 O A:CYS643 4.6 0.0 1.0 CA A:CYS640 4.6 0.0 1.0 CA A:CYS669 4.6 0.0 1.0 H A:CYS669 4.7 0.0 1.0 N A:PHE645 4.7 0.0 1.0 HD1 A:PHE645 4.7 0.0 1.0 HB2 A:LEU668 4.8 0.0 1.0 CA A:PHE645 4.8 0.0 1.0 N A:CYS669 4.8 0.0 1.0 HA A:CYS640 4.8 0.0 1.0 HA A:CYS666 4.8 0.0 1.0 H A:GLN642 4.8 0.0 1.0 HH12 A:ARG795 4.9 0.0 1.0 HH22 A:ARG795 4.9 0.0 1.0 HG2 A:GLN642 4.9 0.0 1.0 C A:GLN642 4.9 0.0 1.0 CB A:SER665 5.0 0.0 1.0

L.Zeng, K.L.Yap, A.V.Ivanov, X.Wang, S.Mujtaba, O.Plotnikova, F.J.Rauscher, M.M.Zhou. Structural Insights Into Human KAP1 Phd Finger-Bromodomain and Its Role in Gene Silencing Nat.Struct.Mol.Biol. V. 15 626 2008.
ISSN: ISSN 1545-9993
PubMed: 18488044
DOI: 10.1038/NSMB.1416