Zinc in PDB 2qn0: Structure of Botulinum Neurotoxin Serotype C1 Light Chain Protease

The structure of Structure of Botulinum Neurotoxin Serotype C1 Light Chain Protease, PDB code: 2qn0 was solved by R.Jin, S.Sikorra, C.M.Stegmann, A.Pich, T.Binz, A.T.Brunger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.67 / 1.75
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	107.010, 107.010, 140.390, 90.00, 90.00, 120.00
R / Rfree (%)	18.8 / 20.5

The binding sites of Zinc atom in the Structure of Botulinum Neurotoxin Serotype C1 Light Chain Protease (pdb code 2qn0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Botulinum Neurotoxin Serotype C1 Light Chain Protease, PDB code: 2qn0:

Zinc binding site 1 out of 1 in the Structure of Botulinum Neurotoxin Serotype C1 Light Chain Protease


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Botulinum Neurotoxin Serotype C1 Light Chain Protease within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn431 b:16.3 occ:1.00 OE1 A:GLU269 2.1 14.2 1.0 NE2 A:HIS233 2.1 15.1 1.0 O A:HOH729 2.1 15.8 1.0 NE2 A:HIS229 2.1 13.0 1.0 CD A:GLU269 2.7 15.0 1.0 OE2 A:GLU269 2.7 15.1 1.0 CD2 A:HIS229 2.9 14.3 1.0 CD2 A:HIS233 3.0 13.7 1.0 CE1 A:HIS233 3.1 15.2 1.0 CE1 A:HIS229 3.2 14.4 1.0 O A:HOH503 3.7 24.8 1.0 OE2 A:GLU230 3.9 14.9 1.0 CG A:HIS229 4.1 13.1 1.0 O A:HOH667 4.2 35.1 1.0 CG A:HIS233 4.2 13.8 1.0 O A:HOH497 4.2 21.6 1.0 ND1 A:HIS233 4.2 14.1 1.0 CG A:GLU269 4.2 13.6 1.0 OH A:TYR375 4.2 17.9 1.0 ND1 A:HIS229 4.2 13.2 1.0 CB A:ALA272 4.4 12.0 1.0 CE1 A:TYR375 4.5 15.9 1.0 OE1 A:GLU230 4.5 13.9 1.0 CD A:GLU230 4.6 15.3 1.0 CA A:GLU269 4.6 14.0 1.0 CZ A:TYR375 4.7 17.0 1.0 CB A:GLU269 4.7 13.9 1.0 O A:HOH929 4.9 56.1 1.0

R.Jin, S.Sikorra, C.M.Stegmann, A.Pich, T.Binz, A.T.Brunger. Structural and Biochemical Studies of Botulinum Neurotoxin Serotype C1 Light Chain Protease: Implications For Dual Substrate Specificity. Biochemistry V. 46 10685 2007.
ISSN: ISSN 0006-2960
PubMed: 17718519
DOI: 10.1021/BI701162D