Zinc in PDB 2qmy: Quinone Reductase 2 in Complex with Adrenochrome

All present enzymatic activity of Quinone Reductase 2 in Complex with Adrenochrome:
1.10.99.2;

The structure of Quinone Reductase 2 in Complex with Adrenochrome, PDB code: 2qmy was solved by Z.Zhang, Y.Fu, L.Buryanovskky, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	83.834, 106.461, 56.605, 90.00, 90.00, 90.00
R / Rfree (%)	19.5 / 25.9

The binding sites of Zinc atom in the Quinone Reductase 2 in Complex with Adrenochrome (pdb code 2qmy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Quinone Reductase 2 in Complex with Adrenochrome, PDB code: 2qmy:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Quinone Reductase 2 in Complex with Adrenochrome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Quinone Reductase 2 in Complex with Adrenochrome within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn231 b:29.7 occ:1.00 ND1 A:HIS173 2.3 24.0 1.0 ND1 A:HIS177 2.3 32.1 1.0 O A:CYS222 2.4 39.5 1.0 SG A:CYS222 2.5 40.2 1.0 CB A:CYS222 2.8 39.9 1.0 CG A:HIS177 3.0 30.9 1.0 C A:CYS222 3.1 39.7 1.0 CG A:HIS173 3.1 23.4 1.0 CE1 A:HIS177 3.3 32.1 1.0 CE1 A:HIS173 3.3 24.1 1.0 CB A:HIS177 3.3 27.3 1.0 CB A:HIS173 3.3 21.9 1.0 CA A:HIS173 3.5 21.9 1.0 CA A:CYS222 3.5 40.5 1.0 N A:THR223 4.0 38.6 1.0 CD2 A:HIS177 4.1 31.5 1.0 NE2 A:HIS177 4.2 33.0 1.0 CD2 A:HIS173 4.3 24.4 1.0 NE2 A:HIS173 4.3 26.1 1.0 N A:HIS173 4.4 21.9 1.0 C A:HIS173 4.4 23.0 1.0 O A:HIS173 4.5 23.8 1.0 CA A:THR223 4.5 37.6 1.0 N A:CYS222 4.8 41.9 1.0 CA A:HIS177 4.8 25.3 1.0 O A:GLN172 4.8 21.3 1.0 CE1 A:HIS227 4.9 45.8 1.0 C A:GLN172 5.0 20.7 1.0 CE1 A:TYR132 5.0 37.5 1.0

Zinc binding site 2 out of 2 in the Quinone Reductase 2 in Complex with Adrenochrome


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Quinone Reductase 2 in Complex with Adrenochrome within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn232 b:26.0 occ:1.00 ND1 B:HIS173 2.3 13.9 1.0 ND1 B:HIS177 2.3 19.6 1.0 O B:CYS222 2.4 27.1 1.0 SG B:CYS222 2.5 19.8 1.0 CB B:CYS222 3.0 22.9 1.0 C B:CYS222 3.1 26.0 1.0 CG B:HIS173 3.2 13.2 1.0 CE1 B:HIS177 3.3 18.0 1.0 CE1 B:HIS173 3.3 13.7 1.0 CG B:HIS177 3.4 18.1 1.0 CB B:HIS173 3.4 13.0 1.0 CA B:CYS222 3.6 24.8 1.0 CA B:HIS173 3.6 12.9 1.0 CB B:HIS177 3.6 13.3 1.0 N B:THR223 4.0 26.7 1.0 CD2 B:HIS173 4.3 15.2 1.0 NE2 B:HIS173 4.4 14.3 1.0 NE2 B:HIS177 4.4 19.7 1.0 CD2 B:HIS177 4.5 19.9 1.0 CA B:THR223 4.5 26.8 1.0 N B:HIS173 4.6 12.8 1.0 C B:HIS173 4.6 13.7 1.0 O B:HIS173 4.7 14.4 1.0 O B:GLN172 4.8 12.9 1.0 N B:CYS222 4.8 25.0 1.0 CE1 B:HIS227 5.0 23.9 1.0 CZ3 B:TRP169 5.0 17.6 1.0

Z.Zhang, Y.Fu, L.Buryanovskky. Quinone Reductase 2 Regulates Catecholamine Oxidation To Be Published.