Zinc in PDB 2qg9: Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli

All present enzymatic activity of Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli:
2.1.3.2;

The structure of Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli, PDB code: 2qg9 was solved by B.Stec, M.K.Williams, K.A.Stieglitz, E.R.Kantrowitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.00 / 2.70
Space group	P 3 2 1
Cell size a, b, c (Å), α, β, γ (°)	122.290, 122.290, 142.410, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / 24.4

The binding sites of Zinc atom in the Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli (pdb code 2qg9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli, PDB code: 2qg9:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn160 b:16.3 occ:1.00 SG B:CYS109 2.2 18.4 1.0 SG B:CYS141 2.2 14.2 1.0 SG B:CYS138 2.3 18.4 1.0 SG B:CYS114 2.4 17.3 1.0 CB B:CYS109 3.0 18.4 1.0 CB B:CYS138 3.1 18.0 1.0 CB B:CYS141 3.5 12.2 1.0 CB B:CYS114 3.5 16.9 1.0 OG B:SER116 3.6 17.6 1.0 N B:CYS141 3.9 13.4 1.0 CA B:CYS141 4.3 13.6 1.0 CB B:ASN111 4.4 17.3 1.0 CA B:CYS109 4.4 16.8 1.0 CB B:SER116 4.5 15.7 1.0 CB B:TYR140 4.6 15.4 1.0 CA B:CYS138 4.6 18.4 1.0 CZ B:PHE125 4.6 14.2 1.0 ND2 B:ASN111 4.8 16.0 1.0 CA B:CYS114 4.8 16.3 1.0 CE2 B:PHE125 4.9 18.4 1.0 C B:TYR140 5.0 13.9 1.0

Zinc binding site 2 out of 2 in the Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of A Regulatory Subunit Mutant D19A of Atcase From E. Coli within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn160 b:17.2 occ:1.00 SG D:CYS109 2.2 17.7 1.0 SG D:CYS138 2.2 18.4 1.0 SG D:CYS114 2.3 18.4 1.0 SG D:CYS141 2.3 18.4 1.0 CB D:CYS114 2.9 18.4 1.0 CB D:CYS109 3.0 18.4 1.0 CB D:CYS138 3.1 17.4 1.0 CB D:CYS141 3.2 17.6 1.0 N D:CYS141 3.5 17.4 1.0 CA D:CYS141 3.9 18.4 1.0 CA D:CYS114 4.2 17.9 1.0 CA D:CYS109 4.3 18.0 1.0 CB D:ASN111 4.4 18.4 1.0 CA D:CYS138 4.5 18.4 1.0 OG D:SER116 4.5 18.4 1.0 ND2 D:ASN111 4.6 18.4 1.0 C D:TYR140 4.6 18.0 1.0 CB D:TYR140 4.6 17.4 1.0 N D:GLU142 4.7 18.4 1.0 C D:CYS141 4.7 18.1 1.0 N D:TYR140 4.8 18.4 1.0 CA D:TYR140 4.8 18.0 1.0 CB D:SER116 4.9 17.5 1.0

B.Stec, M.K.Williams, K.A.Stieglitz, E.R.Kantrowitz. Comparison of Two T-State Structures of Regulatory-Chain Mutants of Escherichia Coli Aspartate Transcarbamoylase Suggests That HIS20 and ASP19 Modulate the Response to Heterotropic Effectors. Acta Crystallogr.,Sect.D V. 63 1243 2007.
ISSN: ISSN 0907-4449
PubMed: 18084072
DOI: 10.1107/S0907444907052985