Atomistry » Zinc » PDB 2ow0-2pcu » 2p53
Atomistry »
  Zinc »
    PDB 2ow0-2pcu »
      2p53 »

Zinc in PDB 2p53: Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate

Enzymatic activity of Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate

All present enzymatic activity of Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate:
3.5.1.25;

Protein crystallography data

The structure of Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate, PDB code: 2p53 was solved by A.A.Fedorov, E.V.Fedorov, R.S.Hall, F.M.Raushel, S.C.Almo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 24.85 / 2.10
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 81.399, 81.399, 206.452, 90.00, 90.00, 120.00
R / Rfree (%) 20.5 / 24.2

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate (pdb code 2p53). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate, PDB code: 2p53:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2p53

Go back to Zinc Binding Sites List in 2p53
Zinc binding site 1 out of 2 in the Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:24.4
occ:1.00
 O71 A:NNG411 1.8 20.3 1.0
OE1 A:GLU131 1.9 20.7 1.0
NE2 A:HIS195 2.0 22.8 1.0
NE2 A:HIS216 2.2 23.0 1.0
CD A:GLU131 2.7 21.3 1.0
OE2 A:GLU131 2.9 19.6 1.0
CD2 A:HIS195 3.0 22.1 1.0
P7 A:NNG411 3.0 27.9 1.0
CE1 A:HIS195 3.1 22.8 1.0
CD2 A:HIS216 3.1 22.4 1.0
O72 A:NNG411 3.2 19.6 1.0
CE1 A:HIS216 3.3 25.5 1.0
NE2 A:GLN59 3.8 24.3 1.0
N2 A:NNG411 4.0 22.5 1.0
CG A:GLU131 4.1 24.1 1.0
NE2 A:HIS143 4.1 29.9 1.0
CG A:HIS195 4.2 22.4 1.0
ND1 A:HIS195 4.2 21.2 1.0
C2 A:NNG411 4.2 24.7 1.0
O A:HOH459 4.2 21.0 1.0
C8 A:NNG411 4.3 22.1 1.0
CG A:HIS216 4.3 23.2 1.0
ND1 A:HIS216 4.3 24.2 1.0
CG2 A:THR215 4.4 19.0 1.0
ND2 A:ASN273 4.8 25.6 1.0
OD1 A:ASN273 4.8 26.0 1.0
CE1 A:HIS143 4.9 29.6 1.0
O3 A:NNG411 4.9 24.9 1.0
CD A:GLN59 4.9 24.9 1.0

Zinc binding site 2 out of 2 in 2p53

Go back to Zinc Binding Sites List in 2p53
Zinc binding site 2 out of 2 in the Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase D273N Mutant Complexed with N-Acetyl Phosphonamidate-D-Glucosamine-6- Phosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn401

b:25.6
occ:1.00
 OE1 B:GLU131 1.8 22.7 1.0
O71 B:NNG411 1.9 26.4 1.0
NE2 B:HIS195 2.0 24.0 1.0
NE2 B:HIS216 2.2 22.4 1.0
CD B:GLU131 2.7 24.4 1.0
OE2 B:GLU131 2.9 23.2 1.0
CE1 B:HIS195 2.9 22.1 1.0
O72 B:NNG411 3.0 24.3 1.0
P7 B:NNG411 3.0 26.7 1.0
CD2 B:HIS195 3.1 23.1 1.0
CD2 B:HIS216 3.1 21.2 1.0
CE1 B:HIS216 3.3 25.2 1.0
NE2 B:GLN59 3.8 29.2 1.0
N2 B:NNG411 4.0 26.0 1.0
CG B:GLU131 4.1 23.2 1.0
ND1 B:HIS195 4.1 22.9 1.0
O B:HOH430 4.1 23.7 1.0
CG B:HIS195 4.2 24.2 1.0
C2 B:NNG411 4.2 24.8 1.0
NE2 B:HIS143 4.2 30.8 1.0
C8 B:NNG411 4.2 22.7 1.0
CG B:HIS216 4.3 23.5 1.0
ND1 B:HIS216 4.3 25.8 1.0
CG2 B:THR215 4.4 21.8 1.0
O3 B:NNG411 4.8 26.0 1.0
OD1 B:ASN273 4.8 26.3 1.0
CD B:GLN59 4.9 30.8 1.0
CE1 B:HIS143 5.0 28.8 1.0
ND2 B:ASN273 5.0 25.5 1.0
CD2 B:HIS143 5.0 30.0 1.0

Reference:

R.S.Hall, S.Brown, A.A.Fedorov, E.V.Fedorov, C.Xu, P.C.Babbitt, S.C.Almo, F.M.Raushel. Structural Diversity Within the Mononuclear and Binuclear Active Sites of N-Acetyl-D-Glucosamine-6-Phosphate Deacetylase. Biochemistry V. 46 7953 2007.
ISSN: ISSN 0006-2960
PubMed: 17567048
DOI: 10.1021/BI700544C
Page generated: Thu Oct 17 02:57:42 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy