Zinc in PDB 2ou2: Acetyltransferase Domain of Human Hiv-1 Tat Interacting Protein, 60KDA, Isoform 3

All present enzymatic activity of Acetyltransferase Domain of Human Hiv-1 Tat Interacting Protein, 60KDA, Isoform 3:
2.3.1.48;

The structure of Acetyltransferase Domain of Human Hiv-1 Tat Interacting Protein, 60KDA, Isoform 3, PDB code: 2ou2 was solved by J.Min, H.Wu, L.Dombrovski, P.Loppnau, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, A.N.Plotnikov, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	83.92 / 2.30
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	107.632, 107.632, 133.731, 90.00, 90.00, 90.00
R / Rfree (%)	22 / 25.2

The binding sites of Zinc atom in the Acetyltransferase Domain of Human Hiv-1 Tat Interacting Protein, 60KDA, Isoform 3 (pdb code 2ou2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Acetyltransferase Domain of Human Hiv-1 Tat Interacting Protein, 60KDA, Isoform 3, PDB code: 2ou2:

Zinc binding site 1 out of 1 in the Acetyltransferase Domain of Human Hiv-1 Tat Interacting Protein, 60KDA, Isoform 3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Acetyltransferase Domain of Human Hiv-1 Tat Interacting Protein, 60KDA, Isoform 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn490 b:38.7 occ:1.00 NE2 A:HIS227 2.1 50.4 1.0 SG A:CYS214 2.2 34.9 1.0 SG A:CYS211 2.3 30.9 1.0 SG A:CYS231 2.4 54.6 1.0 CB A:CYS211 3.1 29.0 1.0 CE1 A:HIS227 3.1 51.5 1.0 CD2 A:HIS227 3.1 50.8 1.0 CB A:CYS214 3.2 33.2 1.0 CB A:CYS231 3.3 57.5 1.0 N A:CYS214 3.7 33.0 1.0 CA A:CYS214 4.0 32.9 1.0 ND1 A:HIS227 4.2 51.0 1.0 CG A:HIS227 4.3 51.9 1.0 CA A:CYS211 4.5 29.6 1.0 CA A:CYS231 4.6 57.5 1.0 C A:PHE213 4.7 33.5 1.0 CB A:LYS216 4.7 36.6 1.0 CB A:PHE213 4.8 33.9 1.0 C A:CYS214 4.8 32.6 1.0 CD1 A:LEU228 4.9 54.6 1.0 N A:LEU215 4.9 32.5 1.0

H.Wu, J.Min, L.Dombrovski, P.Loppnau, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, A.N.Plotnikov. The Crystal Structure of Acetyltransferase Domain of Human Hiv-1 Tat Interacting Protein in Complex with Acetylcoenzyme A. To Be Published.