Zinc in PDB 2ofk: Crystal Structure of 3-Methyladenine Dna Glycosylase I (Tag)

The structure of Crystal Structure of 3-Methyladenine Dna Glycosylase I (Tag), PDB code: 2ofk was solved by A.H.Metz, T.Hollis, B.F.Eichman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	57.455, 63.681, 62.127, 90.00, 106.94, 90.00
R / Rfree (%)	16.1 / 19.6

The binding sites of Zinc atom in the Crystal Structure of 3-Methyladenine Dna Glycosylase I (Tag) (pdb code 2ofk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of 3-Methyladenine Dna Glycosylase I (Tag), PDB code: 2ofk:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of 3-Methyladenine Dna Glycosylase I (Tag)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of 3-Methyladenine Dna Glycosylase I (Tag) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:30.0 occ:1.00 ND1 A:HIS175 2.0 29.5 1.0 NE2 A:HIS17 2.1 30.4 1.0 SG A:CYS4 2.3 31.0 1.0 SG A:CYS179 2.3 31.1 1.0 CE1 A:HIS175 2.9 31.2 1.0 CE1 A:HIS17 2.9 29.2 1.0 CG A:HIS175 3.1 29.2 1.0 CD2 A:HIS17 3.1 28.9 1.0 CB A:CYS179 3.2 33.8 1.0 CB A:CYS4 3.3 30.6 1.0 N A:CYS4 3.4 31.8 1.0 CB A:HIS175 3.5 30.0 1.0 CA A:CYS4 3.9 30.1 1.0 CA A:HIS175 4.0 29.7 1.0 NE2 A:HIS175 4.1 32.5 1.0 ND1 A:HIS17 4.1 28.0 1.0 CD2 A:HIS175 4.2 31.0 1.0 CG A:HIS17 4.2 30.2 1.0 CB A:CYS181 4.3 35.8 1.0 C A:ARG3 4.5 32.7 1.0 CA A:CYS179 4.7 34.2 1.0 N A:ILE176 4.7 30.0 1.0 CZ3 A:TRP21 4.8 29.8 1.0 CA A:ARG3 4.8 33.7 1.0 SG A:CYS181 4.8 36.0 1.0 C A:HIS175 4.8 30.4 1.0 CE3 A:TRP21 5.0 31.8 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of 3-Methyladenine Dna Glycosylase I (Tag)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of 3-Methyladenine Dna Glycosylase I (Tag) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:26.6 occ:1.00 NE2 B:HIS17 2.0 26.7 1.0 ND1 B:HIS175 2.0 24.9 1.0 SG B:CYS4 2.3 27.0 1.0 SG B:CYS179 2.3 25.8 1.0 CE1 B:HIS175 2.9 24.5 1.0 CE1 B:HIS17 3.0 26.3 1.0 CD2 B:HIS17 3.1 26.9 1.0 CG B:HIS175 3.1 22.9 1.0 CB B:CYS179 3.3 26.8 1.0 CB B:CYS4 3.4 28.6 1.0 N B:CYS4 3.6 28.5 1.0 CB B:HIS175 3.6 24.6 1.0 CA B:HIS175 4.0 24.1 1.0 CA B:CYS4 4.1 29.1 1.0 NE2 B:HIS175 4.1 24.9 1.0 ND1 B:HIS17 4.1 27.1 1.0 CB B:CYS181 4.2 28.5 1.0 CG B:HIS17 4.2 25.4 1.0 CD2 B:HIS175 4.2 25.8 1.0 SG B:CYS181 4.6 30.0 1.0 C B:ARG3 4.6 30.2 1.0 CA B:CYS179 4.7 26.9 1.0 N B:ILE176 4.8 25.2 1.0 CA B:ARG3 4.8 30.3 1.0 CZ3 B:TRP21 4.8 25.5 1.0 C B:HIS175 4.9 25.1 1.0 CE3 B:TRP21 5.0 26.8 1.0

A.H.Metz, T.Hollis, B.F.Eichman. Dna Damage Recognition and Repair By 3-Methyladenine Dna Glycosylase I (Tag). Embo J. V. 26 2411 2007.
ISSN: ISSN 0261-4189
PubMed: 17410210
DOI: 10.1038/SJ.EMBOJ.7601649