Zinc in PDB 2l75: Solution Structure of CHD4-PHD2 in Complex with H3K9ME3

The binding sites of Zinc atom in the Solution Structure of CHD4-PHD2 in Complex with H3K9ME3 (pdb code 2l75). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of CHD4-PHD2 in Complex with H3K9ME3, PDB code: 2l75:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of CHD4-PHD2 in Complex with H3K9ME3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of CHD4-PHD2 in Complex with H3K9ME3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn155 b:0.0 occ:1.00 ND1 A:HIS113 2.0 0.0 1.0 SG A:CYS116 2.3 0.0 1.0 SG A:CYS96 2.3 0.0 1.0 SG A:CYS93 2.3 0.0 1.0 HB2 A:HIS113 2.8 0.0 1.0 CE1 A:HIS113 2.9 0.0 1.0 CG A:HIS113 3.0 0.0 1.0 HE1 A:HIS113 3.1 0.0 1.0 HB2 A:CYS96 3.1 0.0 1.0 HB A:VAL95 3.1 0.0 1.0 HB3 A:CYS93 3.3 0.0 1.0 H A:HIS113 3.3 0.0 1.0 CB A:CYS93 3.3 0.0 1.0 CB A:CYS96 3.4 0.0 1.0 H A:CYS96 3.4 0.0 1.0 CB A:HIS113 3.4 0.0 1.0 CB A:CYS116 3.4 0.0 1.0 HB2 A:CYS116 3.4 0.0 1.0 HB2 A:CYS93 3.4 0.0 1.0 HB3 A:CYS116 3.6 0.0 1.0 N A:CYS96 3.9 0.0 1.0 NE2 A:HIS113 4.0 0.0 1.0 N A:HIS113 4.0 0.0 1.0 CD2 A:HIS113 4.0 0.0 1.0 HB3 A:CYS96 4.1 0.0 1.0 HB3 A:ASP98 4.2 0.0 1.0 HB3 A:HIS113 4.2 0.0 1.0 CB A:VAL95 4.2 0.0 1.0 CA A:CYS96 4.3 0.0 1.0 CA A:HIS113 4.3 0.0 1.0 HG13 A:VAL95 4.6 0.0 1.0 HG11 A:VAL95 4.6 0.0 1.0 H A:VAL95 4.7 0.0 1.0 CG1 A:VAL95 4.7 0.0 1.0 CA A:CYS116 4.8 0.0 1.0 CA A:CYS93 4.8 0.0 1.0 HA A:CYS96 4.8 0.0 1.0 C A:VAL95 4.8 0.0 1.0 HA A:TYR112 4.8 0.0 1.0 HG21 A:VAL95 4.9 0.0 1.0 HE2 A:HIS113 4.9 0.0 1.0 H A:CYS116 4.9 0.0 1.0 HG22 A:VAL95 4.9 0.0 1.0 CG2 A:VAL95 5.0 0.0 1.0 H A:ASP98 5.0 0.0 1.0 CA A:VAL95 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of CHD4-PHD2 in Complex with H3K9ME3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of CHD4-PHD2 in Complex with H3K9ME3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn156 b:0.0 occ:1.00 SG A:CYS131 2.3 0.0 1.0 SG A:CYS105 2.3 0.0 1.0 SG A:CYS108 2.3 0.0 1.0 SG A:CYS134 2.3 0.0 1.0 H A:CYS131 3.0 0.0 1.0 HB2 A:CYS134 3.1 0.0 1.0 HB3 A:CYS108 3.2 0.0 1.0 HB3 A:CYS131 3.2 0.0 1.0 CB A:CYS134 3.4 0.0 1.0 CB A:CYS108 3.4 0.0 1.0 CB A:CYS105 3.4 0.0 1.0 CB A:CYS131 3.4 0.0 1.0 HB3 A:CYS105 3.4 0.0 1.0 HB2 A:SER110 3.5 0.0 1.0 HB2 A:CYS105 3.5 0.0 1.0 HG A:SER110 3.5 0.0 1.0 HG1 A:THR107 3.7 0.0 1.0 H A:CYS134 3.7 0.0 1.0 HB3 A:ARG133 3.7 0.0 1.0 N A:CYS131 3.8 0.0 1.0 OG1 A:THR107 3.8 0.0 1.0 H A:CYS108 3.9 0.0 1.0 N A:CYS108 4.1 0.0 1.0 N A:CYS134 4.1 0.0 1.0 CA A:CYS131 4.1 0.0 1.0 HB3 A:CYS134 4.1 0.0 1.0 OG A:SER110 4.2 0.0 1.0 HB2 A:CYS108 4.2 0.0 1.0 CA A:CYS108 4.2 0.0 1.0 HD13 A:LEU130 4.2 0.0 1.0 HB2 A:CYS131 4.3 0.0 1.0 CB A:SER110 4.3 0.0 1.0 CA A:CYS134 4.3 0.0 1.0 H A:SER110 4.4 0.0 1.0 H A:THR107 4.4 0.0 1.0 O A:CYS108 4.4 0.0 1.0 HA A:LEU130 4.5 0.0 1.0 O A:CYS131 4.5 0.0 1.0 HB3 A:LEU130 4.6 0.0 1.0 C A:CYS108 4.6 0.0 1.0 C A:CYS131 4.7 0.0 1.0 CB A:ARG133 4.7 0.0 1.0 HA A:CYS134 4.7 0.0 1.0 CA A:CYS105 4.8 0.0 1.0 H A:ARG133 4.8 0.0 1.0 C A:THR107 4.8 0.0 1.0 C A:LEU130 4.9 0.0 1.0 HB3 A:SER110 4.9 0.0 1.0 C A:ARG133 5.0 0.0 1.0 HB2 A:ARG133 5.0 0.0 1.0

R.E.Mansfield, C.A.Musselman, A.H.Kwan, S.S.Oliver, A.L.Garske, F.Davrazou, J.M.Denu, T.G.Kutateladze, J.P.Mackay. Plant Homeodomain (Phd) Fingers of CHD4 Are Histone H3-Binding Modules with Preference For Unmodified H3K4 and Methylated H3K9 J.Biol.Chem. V. 286 11779 2011.
ISSN: ISSN 0021-9258
PubMed: 21278251
DOI: 10.1074/JBC.M110.208207