Zinc in PDB 2jt2: Solution Structure of the Aquifex Aeolicus Lpxc- Chir-090 Complex

The binding sites of Zinc atom in the Solution Structure of the Aquifex Aeolicus Lpxc- Chir-090 Complex (pdb code 2jt2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Solution Structure of the Aquifex Aeolicus Lpxc- Chir-090 Complex, PDB code: 2jt2:

Zinc binding site 1 out of 1 in the Solution Structure of the Aquifex Aeolicus Lpxc- Chir-090 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of the Aquifex Aeolicus Lpxc- Chir-090 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn336 b:0.0 occ:1.00 O24 A:C90501 2.0 0.0 1.0 NE2 A:HIS74 2.1 0.0 1.0 NE2 A:HIS226 2.1 0.0 1.0 OD1 A:ASP230 2.2 0.0 1.0 O22 A:C90501 2.2 0.0 1.0 OD2 A:ASP230 2.4 0.0 1.0 CG A:ASP230 2.6 0.0 1.0 N23 A:C90501 2.8 0.0 1.0 CD2 A:HIS226 2.8 0.0 1.0 C22 A:C90501 2.8 0.0 1.0 HD2 A:HIS226 2.8 0.0 1.0 CD2 A:HIS74 3.0 0.0 1.0 HD2 A:HIS74 3.1 0.0 1.0 CE1 A:HIS74 3.2 0.0 1.0 CE1 A:HIS226 3.3 0.0 1.0 HE1 A:HIS74 3.5 0.0 1.0 HD2 A:PHE229 3.5 0.0 1.0 HE1 A:HIS226 3.7 0.0 1.0 HN23 A:C90501 3.7 0.0 1.0 HG3 A:GLU73 3.8 0.0 1.0 HB A:THR179 3.8 0.0 1.0 HG1 A:THR179 3.9 0.0 1.0 CG A:HIS226 4.1 0.0 1.0 CB A:ASP230 4.1 0.0 1.0 H213 A:C90501 4.1 0.0 1.0 CG A:HIS74 4.2 0.0 1.0 ND1 A:HIS74 4.3 0.0 1.0 HA A:THR179 4.3 0.0 1.0 ND1 A:HIS226 4.3 0.0 1.0 H211 A:C90501 4.3 0.0 1.0 C18 A:C90501 4.3 0.0 1.0 HE2 A:PHE229 4.4 0.0 1.0 HG2 A:GLU73 4.4 0.0 1.0 HE2 A:HIS253 4.5 0.0 1.0 HA A:ASP230 4.5 0.0 1.0 CD2 A:PHE229 4.5 0.0 1.0 CB A:THR179 4.6 0.0 1.0 CG A:GLU73 4.6 0.0 1.0 HB3 A:ASP230 4.6 0.0 1.0 OG1 A:THR179 4.6 0.0 1.0 HB2 A:ASP230 4.7 0.0 1.0 C21 A:C90501 4.7 0.0 1.0 HN17 A:C90501 4.7 0.0 1.0 HO20 A:C90501 4.7 0.0 1.0 CA A:ASP230 4.8 0.0 1.0 H A:ASP230 4.8 0.0 1.0 OE2 A:GLU73 4.8 0.0 1.0 O A:HIS226 4.9 0.0 1.0 N17 A:C90501 4.9 0.0 1.0 CE2 A:PHE229 4.9 0.0 1.0 CA A:THR179 4.9 0.0 1.0 H18 A:C90501 5.0 0.0 1.0

A.W.Barb, L.Jiang, C.R.Raetz, P.Zhou. Structure of the Deacetylase Lpxc Bound to the Antibiotic Chir-090: Time-Dependent Inhibition and Specificity in Ligand Binding Proc.Natl.Acad.Sci.Usa V. 104 18433 2007.
ISSN: ISSN 0027-8424
PubMed: 18025458
DOI: 10.1073/PNAS.0709412104