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Atomistry » Zinc » PDB 2ja8-2jt6 » 2jew » |
Zinc in PDB 2jew: Crystal Structure of ((2S)-5-Amino-2-((1-N-Propyl-1H-Imidazol-4-Yl) Methyl)Pentanoic Acid) UK396,082 A Tafia Inhibitor, Bound to Activated Porcine Pancreatic CarboxypeptidasebEnzymatic activity of Crystal Structure of ((2S)-5-Amino-2-((1-N-Propyl-1H-Imidazol-4-Yl) Methyl)Pentanoic Acid) UK396,082 A Tafia Inhibitor, Bound to Activated Porcine Pancreatic Carboxypeptidaseb
All present enzymatic activity of Crystal Structure of ((2S)-5-Amino-2-((1-N-Propyl-1H-Imidazol-4-Yl) Methyl)Pentanoic Acid) UK396,082 A Tafia Inhibitor, Bound to Activated Porcine Pancreatic Carboxypeptidaseb:
3.4.17.2; Protein crystallography data
The structure of Crystal Structure of ((2S)-5-Amino-2-((1-N-Propyl-1H-Imidazol-4-Yl) Methyl)Pentanoic Acid) UK396,082 A Tafia Inhibitor, Bound to Activated Porcine Pancreatic Carboxypeptidaseb, PDB code: 2jew
was solved by
D.G.Brown,
R.S.Moore,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of ((2S)-5-Amino-2-((1-N-Propyl-1H-Imidazol-4-Yl) Methyl)Pentanoic Acid) UK396,082 A Tafia Inhibitor, Bound to Activated Porcine Pancreatic Carboxypeptidaseb
(pdb code 2jew). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of ((2S)-5-Amino-2-((1-N-Propyl-1H-Imidazol-4-Yl) Methyl)Pentanoic Acid) UK396,082 A Tafia Inhibitor, Bound to Activated Porcine Pancreatic Carboxypeptidaseb, PDB code: 2jew: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 2jewGo back to Zinc Binding Sites List in 2jew
Zinc binding site 1 out
of 2 in the Crystal Structure of ((2S)-5-Amino-2-((1-N-Propyl-1H-Imidazol-4-Yl) Methyl)Pentanoic Acid) UK396,082 A Tafia Inhibitor, Bound to Activated Porcine Pancreatic Carboxypeptidaseb
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 2jewGo back to Zinc Binding Sites List in 2jew
Zinc binding site 2 out
of 2 in the Crystal Structure of ((2S)-5-Amino-2-((1-N-Propyl-1H-Imidazol-4-Yl) Methyl)Pentanoic Acid) UK396,082 A Tafia Inhibitor, Bound to Activated Porcine Pancreatic Carboxypeptidaseb
Mono view Stereo pair view
Reference:
M.E.Bunnage,
J.Blagg,
J.Steele,
D.R.Owen,
C.Allerton,
A.B.Mcelroy,
D.Miller,
T.Ringer,
K.Butcher,
K.Beaumont,
K.Evans,
A.J.Gray,
S.J.Holland,
N.Feeder,
R.S.Moore,
D.G.Brown.
Discovery of Potent & Selective Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor For the Treatment of Thrombosis. J. Med. Chem. V. 50 6095 2007.
Page generated: Thu Oct 17 01:12:43 2024
ISSN: ISSN 0022-2623 PubMed: 17990866 DOI: 10.1021/JM0702433 |
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