Zinc in PDB 2izo: Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex

The structure of Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex, PDB code: 2izo was solved by A.S.Dore, M.L.Kilkenny, S.M.Roe, L.H.Pearl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	93.986, 99.774, 99.958, 90.00, 90.00, 90.00
R / Rfree (%)	25 / 31.2

The structure of Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex also contains other interesting chemical elements:

Magnesium

(Mg)

4 atoms

The binding sites of Zinc atom in the Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex (pdb code 2izo). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex, PDB code: 2izo:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1347 b:83.9 occ:1.00 OD1 A:ASP170 2.2 46.3 1.0 O A:HOH2014 3.0 32.1 1.0 CG A:ASP170 3.0 46.3 1.0 OD2 A:ASP170 3.3 46.8 1.0 CB A:ASP170 4.4 45.9 1.0 N A:ASP170 4.5 45.7 1.0 ND2 A:ASN27 4.6 45.4 1.0 NE2 A:GLN31 4.6 47.7 1.0 CA A:ASP170 4.6 45.8 1.0 CB A:GLN169 4.6 45.9 1.0 C A:GLN169 4.7 45.8 1.0 O A:GLN169 4.8 46.0 1.0

Zinc binding site 2 out of 4 in the Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1246 b:87.1 occ:1.00 OE1 B:GLU160 3.3 50.5 1.0 O B:LYS159 3.6 50.0 1.0 NZ B:LYS159 4.0 49.1 1.0 CD B:GLU160 4.1 50.3 1.0 CE B:LYS159 4.3 49.5 1.0 C B:LYS159 4.4 50.0 1.0 CG B:GLU160 4.7 50.2 1.0 OE2 B:GLU160 4.8 50.1 1.0

Zinc binding site 3 out of 4 in the Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1251 b:74.4 occ:1.00 OD1 C:ASP207 2.6 51.3 1.0 OD2 C:ASP207 2.7 51.5 1.0 CG C:ASP207 3.0 51.2 1.0 OE1 C:GLU203 3.0 52.5 1.0 NZ C:LYS206 3.6 51.4 1.0 CD C:GLU203 4.3 51.8 1.0 CB C:ASP207 4.5 51.0 1.0 O C:GLU203 4.7 49.8 1.0 CB C:GLU203 4.7 49.4 1.0 CE C:MET204 4.8 51.3 1.0 O C:HOH2003 4.9 34.2 1.0 CG C:GLU203 4.9 50.5 1.0 CE C:LYS206 4.9 51.5 1.0

Zinc binding site 4 out of 4 in the Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1252 b:75.3 occ:1.00 O C:HOH2029 2.8 31.7 1.0 CE1 C:HIS240 2.8 46.5 1.0 ND1 C:HIS240 3.0 46.1 1.0 OE1 C:GLU234 3.0 50.2 1.0 OE2 C:GLU234 3.2 49.5 1.0 O C:HOH2026 3.2 45.3 1.0 CD C:GLU234 3.3 49.7 1.0 NE2 C:HIS240 4.1 46.7 1.0 O C:GLY238 4.3 47.1 1.0 CG C:HIS240 4.3 46.2 1.0 CG C:GLU234 4.4 49.0 1.0 CD2 C:HIS240 4.9 46.6 1.0

A.S.Dore, M.L.Kilkenny, S.A.Jones, A.W.Oliver, S.M.Roe, S.D.Bell, L.H.Pearl. Structure of An Archaeal PCNA1-PCNA2-FEN1 Complex: Elucidating Pcna Subunit and Client Enzyme Specificity. Nucleic Acids Res. V. 34 4515 2006.
ISSN: ISSN 0305-1048
PubMed: 16945955
DOI: 10.1093/NAR/GKL623