Zinc in PDB 2iom: Mouse P53 Core Domain Soaked with 2-Propanol

The structure of Mouse P53 Core Domain Soaked with 2-Propanol, PDB code: 2iom was solved by W.C.Ho, C.Luo, K.Zhao, X.Chai, M.X.Fitzgerald, R.Marmorstein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	92.299, 44.541, 62.915, 90.00, 126.23, 90.00
R / Rfree (%)	20.9 / 24.6

The binding sites of Zinc atom in the Mouse P53 Core Domain Soaked with 2-Propanol (pdb code 2iom). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Mouse P53 Core Domain Soaked with 2-Propanol, PDB code: 2iom:

Zinc binding site 1 out of 1 in the Mouse P53 Core Domain Soaked with 2-Propanol


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mouse P53 Core Domain Soaked with 2-Propanol within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2001 b:28.8 occ:1.00 ND1 A:HIS176 2.0 31.2 1.0 SG A:CYS235 2.3 31.3 1.0 SG A:CYS239 2.3 28.9 1.0 SG A:CYS173 2.4 25.7 1.0 CE1 A:HIS176 2.9 31.1 1.0 CG A:HIS176 3.1 31.2 1.0 CB A:CYS239 3.2 30.4 1.0 CB A:CYS235 3.5 28.1 1.0 CB A:HIS176 3.5 30.5 1.0 CB A:CYS173 3.6 27.0 1.0 CA A:CYS235 3.9 27.6 1.0 N A:CYS173 4.0 26.3 1.0 NE2 A:HIS176 4.0 28.7 1.0 CD2 A:HIS176 4.1 31.2 1.0 O A:HOH1159 4.2 44.3 1.0 N A:ASN236 4.3 27.4 1.0 CA A:CYS173 4.4 27.4 1.0 N A:HIS176 4.5 33.0 1.0 CA A:CYS239 4.5 31.8 1.0 C A:CYS235 4.6 28.2 1.0 CA A:HIS176 4.6 32.9 1.0 O A:HOH1035 4.7 25.5 1.0 O A:MET234 4.7 26.2 1.0 O A:CYS173 4.9 26.1 1.0

W.C.Ho, C.Luo, K.Zhao, X.Chai, M.X.Fitzgerald, R.Marmorstein. High-Resolution Structure of the P53 Core Domain: Implications For Binding Small-Molecule Stabilizing Compounds. Acta Crystallogr.,Sect.D V. 62 1484 2006.
ISSN: ISSN 0907-4449
PubMed: 17139084
DOI: 10.1107/S090744490603890X