Atomistry » Zinc » PDB 2hap-2hqh » 2hpm
Atomistry »
  Zinc »
    PDB 2hap-2hqh »
      2hpm »

Zinc in PDB 2hpm: Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III

Enzymatic activity of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III

All present enzymatic activity of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III:
2.7.7.7;

Protein crystallography data

The structure of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III, PDB code: 2hpm was solved by S.Bailey, R.A.Wing, T.A.Steitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 3.70
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 174.442, 185.724, 125.836, 90.00, 90.00, 90.00
R / Rfree (%) 24 / 31.1

Other elements in 2hpm:

The structure of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms
Chlorine (Cl) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III (pdb code 2hpm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III, PDB code: 2hpm:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2hpm

Go back to Zinc Binding Sites List in 2hpm
Zinc binding site 1 out of 2 in the Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1221

b:94.4
occ:1.00
 OD2 A:ASP20 1.9 0.8 1.0
NE2 A:HIS47 1.9 0.1 1.0
NE2 A:HIS214 2.2 1.0 1.0
CE1 A:HIS47 2.8 0.7 1.0
CG A:ASP20 2.9 0.1 1.0
CD2 A:HIS47 2.9 0.3 1.0
CE1 A:HIS214 3.0 0.8 1.0
OD1 A:ASP20 3.2 0.9 1.0
CD2 A:HIS214 3.2 0.4 1.0
ND1 A:HIS47 3.9 0.7 1.0
CG A:HIS47 4.0 0.3 1.0
ND1 A:HIS214 4.0 0.6 1.0
CG A:HIS214 4.2 0.5 1.0
CB A:ASP20 4.3 0.1 1.0
CE1 A:HIS13 4.4 0.8 1.0
ND1 A:HIS13 4.5 0.5 1.0
ZN A:ZN1222 4.6 0.2 1.0
CZ A:PHE244 4.6 0.2 1.0
NE2 A:HIS13 4.8 0.5 1.0

Zinc binding site 2 out of 2 in 2hpm

Go back to Zinc Binding Sites List in 2hpm
Zinc binding site 2 out of 2 in the Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1222

b:0.2
occ:1.00
 OE1 A:GLU72 1.6 0.6 1.0
OD1 A:ASP212 2.3 0.1 1.0
NE2 A:HIS13 2.5 0.5 1.0
CD A:GLU72 2.6 0.5 1.0
NE2 A:HIS11 2.8 0.7 1.0
OD2 A:ASP212 2.8 0.3 1.0
CG A:ASP212 2.9 0.6 1.0
OE2 A:GLU72 2.9 0.1 1.0
CE1 A:HIS13 3.1 0.8 1.0
CE1 A:HIS11 3.2 0.5 1.0
CD2 A:HIS13 3.6 0.2 1.0
CE1 A:HIS47 3.7 0.7 1.0
CD2 A:HIS11 3.9 0.8 1.0
CG A:GLU72 3.9 0.7 1.0
CE1 A:HIS214 4.0 0.8 1.0
SG A:CYS145 4.0 0.2 1.0
NE2 A:HIS47 4.1 0.1 1.0
ND1 A:HIS13 4.2 0.5 1.0
ND1 A:HIS95 4.2 0.0 1.0
ND1 A:HIS11 4.3 0.6 1.0
CB A:CYS145 4.4 0.6 1.0
CB A:ASP212 4.4 0.2 1.0
CG A:HIS13 4.5 0.3 1.0
CB A:GLU72 4.5 0.1 1.0
ND1 A:HIS47 4.5 0.7 1.0
NE2 A:HIS214 4.6 1.0 1.0
ZN A:ZN1221 4.6 94.4 1.0
CE1 A:HIS95 4.6 0.6 1.0
CG A:HIS11 4.7 0.9 1.0

Reference:

S.Bailey, R.A.Wing, T.A.Steitz. The Structure of T. Aquaticus Dna Polymerase III Is Distinct From Eukaryotic Replicative Dna Polymerases. Cell(Cambridge,Mass.) V. 126 893 2006.
ISSN: ISSN 0092-8674
PubMed: 16959569
DOI: 10.1016/J.CELL.2006.07.027
Page generated: Thu Oct 17 00:40:49 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy