Zinc in PDB 2ga6: The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive

The structure of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive, PDB code: 2ga6 was solved by D.Su, Z.Lou, F.Sun, Y.Zhai, H.Yang, Z.Rao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.70
Space group	C 2 2 21 1
Cell size a, b, c (Å), α, β, γ (°)	159.737, 322.703, 162.153, 90.00, 90.00, 90.00
R / Rfree (%)	21.9 / 26.7

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 48;

Binding sites:

The binding sites of Zinc atom in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive (pdb code 2ga6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 48 binding sites of Zinc where determined in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive, PDB code: 2ga6:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Zinc binding site 1 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn998 b:72.3 occ:1.00 SG A:CYS74 2.2 24.2 1.0 CD2 A:HIS83 2.3 57.9 1.0 SG A:CYS77 2.4 27.3 1.0 NE2 A:HIS83 2.4 59.8 1.0 CB A:CYS90 2.5 40.5 1.0 SG A:CYS90 2.6 36.5 1.0 CA A:CYS90 2.7 52.3 1.0 N A:CYS90 3.0 58.0 1.0 CG A:HIS83 3.5 58.0 1.0 CE1 A:HIS83 3.7 63.3 1.0 CB A:CYS74 3.9 29.1 1.0 CB A:TYR76 4.1 28.2 1.0 N A:CYS77 4.1 29.7 1.0 CB A:CYS77 4.2 28.2 1.0 ND1 A:HIS83 4.2 61.4 1.0 C A:CYS90 4.2 53.5 1.0 C A:PHE89 4.3 60.0 1.0 O A:HOH1022 4.5 29.1 1.0 CA A:CYS77 4.6 30.8 1.0 CB A:HIS83 4.6 54.4 1.0 O A:HOH1008 4.7 56.2 1.0 C A:TYR76 4.7 29.0 1.0 CD1 A:TYR76 4.8 27.4 1.0 CG A:TYR76 4.9 28.9 1.0 CA A:TYR76 4.9 29.0 1.0 O A:CYS90 4.9 57.5 1.0 N A:ASP91 5.0 51.7 1.0

Zinc binding site 2 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn999 b:43.4 occ:1.00 SG A:CYS120 2.4 37.0 1.0 SG A:CYS128 2.4 45.2 1.0 SG A:CYS117 2.5 33.9 1.0 O A:HOH1045 2.6 16.9 1.0 CB A:CYS120 3.1 32.0 1.0 CB A:CYS117 3.2 28.2 1.0 N A:SER129 3.4 52.6 1.0 CB A:CYS128 3.5 44.0 1.0 N A:CYS120 3.6 32.9 1.0 CA A:CYS128 3.7 45.0 1.0 CA A:CYS120 3.9 32.6 1.0 C A:CYS128 4.0 48.0 1.0 OG A:SER129 4.1 50.8 1.0 CA A:SER129 4.3 54.0 1.0 CB A:VAL119 4.6 33.7 1.0 CA A:CYS117 4.7 27.3 1.0 CB A:SER129 4.7 52.5 1.0 C A:VAL119 4.7 31.6 1.0 C A:CYS120 4.8 32.3 1.0 N A:GLY121 4.9 31.9 1.0 CG1 A:VAL119 4.9 35.0 1.0

Zinc binding site 3 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn998 b:67.5 occ:1.00 SG B:CYS74 2.1 19.8 1.0 SG B:CYS77 2.3 25.3 1.0 CA B:CYS90 2.3 44.9 1.0 SG B:CYS90 2.4 40.1 1.0 CD2 B:HIS83 2.4 34.0 1.0 CB B:CYS90 2.4 34.7 1.0 NE2 B:HIS83 2.5 31.7 1.0 N B:CYS90 2.6 48.2 1.0 CG B:HIS83 3.5 37.2 1.0 O B:HOH1014 3.5 25.6 1.0 CE1 B:HIS83 3.5 36.0 1.0 CB B:CYS74 3.6 26.9 1.0 C B:PHE89 3.8 50.5 1.0 C B:CYS90 3.8 45.1 1.0 ND1 B:HIS83 4.0 39.4 1.0 CB B:CYS77 4.1 23.1 1.0 N B:CYS77 4.3 26.1 1.0 N B:ASP91 4.4 45.3 1.0 O B:PHE89 4.5 48.5 1.0 CB B:TYR76 4.5 26.6 1.0 CB B:HIS83 4.5 41.7 1.0 CA B:PHE89 4.7 55.2 1.0 CA B:CYS77 4.7 24.5 1.0 O B:CYS90 4.7 45.9 1.0

Zinc binding site 4 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn999 b:74.9 occ:1.00 SG B:CYS117 2.4 42.9 1.0 O B:HOH1036 2.7 26.4 1.0 SG B:CYS128 2.7 42.8 1.0 SG B:CYS120 2.9 37.8 1.0 N B:SER129 3.3 51.7 1.0 CB B:CYS120 3.4 36.4 1.0 CB B:CYS128 3.9 42.8 1.0 N B:CYS120 4.0 36.4 1.0 CA B:CYS128 4.0 47.4 1.0 CA B:SER129 4.2 51.4 1.0 C B:CYS128 4.2 49.1 1.0 CB B:VAL119 4.3 39.3 1.0 CB B:CYS117 4.3 42.4 1.0 CA B:CYS120 4.4 35.1 1.0 CG1 B:VAL119 4.5 38.9 1.0 OG B:SER129 4.7 52.0 1.0 C B:VAL119 4.8 37.9 1.0 CB B:SER129 4.9 52.5 1.0

Zinc binding site 5 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn998 b:84.3 occ:1.00 SG C:CYS74 2.3 28.1 1.0 CD2 C:HIS83 2.3 50.9 1.0 SG C:CYS77 2.4 32.4 1.0 CB C:CYS90 2.4 46.7 1.0 SG C:CYS90 2.6 42.2 1.0 NE2 C:HIS83 2.7 52.7 1.0 CA C:CYS90 3.0 59.8 1.0 N C:CYS90 3.2 64.8 1.0 CG C:HIS83 3.5 52.0 1.0 CE1 C:HIS83 3.9 56.8 1.0 CB C:TYR76 4.0 34.6 1.0 N C:CYS77 4.0 31.9 1.0 CB C:CYS74 4.0 35.5 1.0 ND2 C:ASN85 4.1 74.0 1.0 CB C:CYS77 4.1 31.1 1.0 C C:PHE89 4.2 66.0 1.0 ND1 C:HIS83 4.3 56.3 1.0 CB C:HIS83 4.5 47.8 1.0 C C:CYS90 4.5 62.1 1.0 CA C:CYS77 4.5 32.4 1.0 CD1 C:TYR76 4.5 34.2 1.0 C C:TYR76 4.6 33.6 1.0 CG C:TYR76 4.7 35.1 1.0 CA C:TYR76 4.8 34.8 1.0 O C:PHE89 4.8 65.2 1.0 CA C:PHE89 4.9 67.0 1.0

Zinc binding site 6 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn999 b:45.4 occ:1.00 SG C:CYS120 2.4 35.4 1.0 SG C:CYS128 2.5 54.5 1.0 SG C:CYS117 2.5 39.7 1.0 O C:HOH1042 2.7 14.2 1.0 N C:SER129 3.4 53.4 1.0 CB C:CYS120 3.4 34.0 1.0 CB C:CYS117 3.4 35.3 1.0 N C:CYS120 3.8 37.7 1.0 CB C:CYS128 3.9 50.5 1.0 CA C:SER129 4.1 55.5 1.0 CA C:CYS128 4.2 49.5 1.0 CB C:SER129 4.2 54.0 1.0 CA C:CYS120 4.2 35.6 1.0 C C:CYS128 4.2 50.4 1.0 NZ C:LYS124 4.4 38.5 1.0 CB C:VAL119 4.5 38.1 1.0 C C:VAL119 4.8 38.6 1.0 OG C:SER129 4.9 49.2 1.0 CA C:CYS117 4.9 35.8 1.0

Zinc binding site 7 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn998 b:75.6 occ:1.00 NE2 D:HIS83 2.1 34.0 1.0 SG D:CYS77 2.2 35.1 1.0 SG D:CYS74 2.2 36.1 1.0 CA D:CYS90 2.4 58.1 1.0 CB D:CYS90 2.4 50.1 1.0 SG D:CYS90 2.4 52.5 1.0 N D:CYS90 2.5 59.3 1.0 CD2 D:HIS83 2.6 36.1 1.0 CE1 D:HIS83 3.0 36.1 1.0 CG D:HIS83 3.6 39.7 1.0 ND1 D:HIS83 3.8 40.4 1.0 C D:PHE89 3.8 59.2 1.0 CB D:CYS74 3.8 34.2 1.0 O D:HOH1012 3.9 71.2 1.0 C D:CYS90 3.9 60.4 1.0 CB D:CYS77 4.0 34.7 1.0 N D:CYS77 4.3 29.7 1.0 CB D:TYR76 4.5 35.2 1.0 CA D:PHE89 4.5 62.3 1.0 O D:PHE89 4.6 57.4 1.0 N D:ASP91 4.7 60.2 1.0 CA D:CYS77 4.7 32.8 1.0 O D:CYS90 4.7 63.8 1.0 CB D:HIS83 4.9 45.1 1.0 CD1 D:TYR76 5.0 39.0 1.0

Zinc binding site 8 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn999 b:63.8 occ:1.00 SG D:CYS128 2.2 45.7 1.0 SG D:CYS120 2.3 47.1 1.0 SG D:CYS117 2.5 38.9 1.0 O D:HOH1028 2.6 24.2 1.0 CB D:CYS120 2.7 37.5 1.0 N D:CYS120 2.9 38.1 1.0 CA D:CYS120 3.3 39.1 1.0 CB D:CYS117 3.7 37.5 1.0 CB D:CYS128 3.9 49.6 1.0 CB D:VAL119 3.9 33.4 1.0 C D:VAL119 4.0 36.3 1.0 N D:SER129 4.1 64.2 1.0 OG D:SER129 4.3 59.2 1.0 NZ D:LYS124 4.4 47.9 1.0 CA D:VAL119 4.4 34.4 1.0 CG1 D:VAL119 4.5 31.4 1.0 C D:CYS120 4.6 39.3 1.0 N D:VAL119 4.6 37.0 1.0 CA D:CYS128 4.6 54.1 1.0 CA D:SER129 4.7 65.4 1.0 C D:CYS128 4.8 58.7 1.0 N D:GLY121 4.8 38.2 1.0

Zinc binding site 9 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 9 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn998 b:73.8 occ:1.00 CD2 E:HIS83 2.3 43.4 1.0 SG E:CYS77 2.3 26.0 1.0 SG E:CYS74 2.3 25.8 1.0 NE2 E:HIS83 2.4 46.3 1.0 CB E:CYS90 2.5 42.5 1.0 SG E:CYS90 2.6 33.8 1.0 N E:CYS90 3.2 58.3 1.0 CA E:CYS90 3.4 53.2 1.0 N E:CYS77 3.5 23.4 1.0 CG E:HIS83 3.6 48.4 1.0 CB E:CYS77 3.6 23.9 1.0 CE1 E:HIS83 3.7 49.9 1.0 CB E:TYR76 3.7 20.9 1.0 CA E:CYS77 3.9 23.1 1.0 CB E:CYS74 4.2 30.8 1.0 C E:TYR76 4.2 24.1 1.0 ND1 E:HIS83 4.3 50.5 1.0 C E:PHE89 4.3 62.1 1.0 CA E:TYR76 4.5 23.9 1.0 CG E:TYR76 4.6 25.0 1.0 CD1 E:TYR76 4.6 26.5 1.0 CB E:HIS83 4.6 48.9 1.0 C E:CYS90 4.7 53.1 1.0 ND2 E:ASN85 4.8 81.5 1.0 N E:TYR76 4.9 26.7 1.0 CA E:PHE89 4.9 65.2 1.0 O E:CYS90 5.0 57.3 1.0

Zinc binding site 10 out of 48 in the The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 10 of The Crystal Structure of Sars NSP10 Without Zinc Ion As Additive within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn999 b:44.7 occ:1.00 SG E:CYS117 2.4 37.2 1.0 SG E:CYS128 2.5 41.7 1.0 SG E:CYS120 2.5 43.3 1.0 O E:HOH1041 2.5 23.8 1.0 CB E:CYS117 3.2 34.1 1.0 CB E:CYS120 3.4 36.0 1.0 CB E:CYS128 3.6 43.0 1.0 N E:SER129 3.8 50.5 1.0 N E:CYS120 3.8 38.2 1.0 CA E:CYS128 3.9 43.5 1.0 CA E:CYS120 4.2 36.9 1.0 C E:CYS128 4.2 46.5 1.0 OG E:SER129 4.2 49.5 1.0 NZ E:LYS124 4.4 42.7 1.0 CB E:VAL119 4.6 37.9 1.0 CA E:CYS117 4.7 35.8 1.0 CA E:SER129 4.7 55.0 1.0 C E:VAL119 4.9 38.5 1.0 CB E:SER129 5.0 52.9 1.0 C E:CYS120 5.0 36.6 1.0

D.Su, Z.Lou, F.Sun, Y.Zhai, H.Yang, R.Zhang, A.Joachimiak, X.C.Zhang, M.Bartlam, Z.Rao. Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein NSP10 J.Virol. V. 80 7902 2006.
ISSN: ISSN 0022-538X
PubMed: 16873247
DOI: 10.1128/JVI.00483-06