Zinc in PDB 2g43: Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot)

All present enzymatic activity of Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot):
3.1.2.15;

The structure of Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot), PDB code: 2g43 was solved by F.E.Reyes-Turcu, J.R.Horton, J.E.Mullally, A.Heroux, X.Cheng, K.D.Wilkinson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.00 / 2.09
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	61.380, 86.180, 59.900, 90.00, 99.29, 90.00
R / Rfree (%)	22.8 / 27.4

The binding sites of Zinc atom in the Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot) (pdb code 2g43). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot), PDB code: 2g43:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:42.5 occ:1.00 ND1 A:HIS71 2.0 32.6 1.0 SG A:CYS41 2.3 39.2 1.0 SG A:CYS58 2.3 31.3 1.0 SG A:CYS38 2.3 32.9 1.0 CE1 A:HIS71 2.9 35.0 1.0 CG A:HIS71 3.1 32.4 1.0 CB A:CYS38 3.2 32.9 1.0 CB A:CYS41 3.3 43.7 1.0 CB A:CYS58 3.3 28.0 1.0 CB A:HIS71 3.5 30.8 1.0 N A:CYS41 3.8 45.2 1.0 N A:CYS58 3.9 27.0 1.0 NE2 A:HIS71 4.1 34.3 1.0 CA A:CYS41 4.1 44.5 1.0 CD2 A:HIS71 4.2 33.5 1.0 CB A:ASN69 4.2 40.1 1.0 CA A:CYS58 4.2 28.0 1.0 ND2 A:ASN69 4.3 43.1 1.0 C A:LYS40 4.4 45.6 1.0 CA A:CYS38 4.6 34.0 1.0 CB A:LYS40 4.7 47.1 1.0 C A:CYS41 4.8 46.5 1.0 CG A:ASN69 4.8 43.8 1.0 CA A:HIS71 4.8 28.3 1.0 N A:HIS71 4.8 31.0 1.0 CA A:LYS40 4.9 45.7 1.0 N A:LYS40 4.9 44.5 1.0 CB A:MET43 4.9 49.8 1.0 N A:ASN69 5.0 38.3 1.0 O A:LYS40 5.0 47.2 1.0

Zinc binding site 2 out of 2 in the Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn131 b:36.6 occ:1.00 ND1 B:HIS71 2.1 24.6 1.0 SG B:CYS38 2.3 25.1 1.0 SG B:CYS41 2.3 32.3 1.0 SG B:CYS58 2.4 27.2 1.0 CE1 B:HIS71 3.0 25.7 1.0 CG B:HIS71 3.1 24.2 1.0 CB B:CYS38 3.2 25.2 1.0 CB B:CYS58 3.4 24.1 1.0 CB B:HIS71 3.4 24.4 1.0 CB B:CYS41 3.5 33.6 1.0 N B:CYS41 3.8 36.9 1.0 N B:CYS58 3.9 24.0 1.0 NE2 B:HIS71 4.2 26.4 1.0 CA B:CYS41 4.2 35.8 1.0 CD2 B:HIS71 4.2 25.4 1.0 CA B:CYS58 4.3 24.5 1.0 CB B:LYS40 4.3 36.5 1.0 CB B:ASN69 4.4 35.6 1.0 C B:LYS40 4.4 35.9 1.0 ND2 B:ASN69 4.5 39.4 1.0 CA B:CYS38 4.7 26.0 1.0 CA B:LYS40 4.7 36.0 1.0 CA B:HIS71 4.7 25.2 1.0 N B:LYS40 4.7 34.6 1.0 N B:HIS71 4.8 25.6 1.0 C B:CYS41 4.8 37.4 1.0 CB B:MET43 4.9 40.4 1.0 CG B:ASN69 5.0 39.9 1.0

F.E.Reyes-Turcu, J.R.Horton, J.E.Mullally, A.Heroux, X.Cheng, K.D.Wilkinson. The Ubiquitin Binding Domain Znf Ubp Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin. Cell(Cambridge,Mass.) V. 124 1197 2006.
ISSN: ISSN 0092-8674
PubMed: 16564012
DOI: 10.1016/J.CELL.2006.02.038