Zinc in PDB 2g3f: Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue

All present enzymatic activity of Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue:
3.5.2.7;

The structure of Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue, PDB code: 2g3f was solved by Y.Yu, Y.H.Liang, X.D.Su, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.91 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	57.530, 106.080, 66.310, 90.00, 90.20, 90.00
R / Rfree (%)	18.5 / 21.6

The binding sites of Zinc atom in the Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue (pdb code 2g3f). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue, PDB code: 2g3f:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1601 b:13.0 occ:1.00 O A:HOH1739 2.1 12.6 1.0 NE2 A:HIS82 2.1 11.8 1.0 NE2 A:HIS80 2.2 7.5 1.0 NE2 A:HIS249 2.3 9.6 1.0 OD1 A:ASP324 2.4 10.0 1.0 CD2 A:HIS249 3.1 8.4 1.0 CE1 A:HIS82 3.1 8.3 1.0 CE1 A:HIS80 3.1 7.7 1.0 CD2 A:HIS82 3.1 9.1 1.0 CD2 A:HIS80 3.2 7.6 1.0 CE1 A:HIS249 3.3 9.9 1.0 CG A:ASP324 3.4 10.2 1.0 OD2 A:ASP324 3.7 9.5 1.0 NE2 A:HIS272 4.1 17.6 1.0 ND1 A:HIS82 4.2 9.4 1.0 CG A:HIS249 4.3 8.7 1.0 ND1 A:HIS80 4.3 8.3 1.0 CG A:HIS82 4.3 9.3 1.0 CG A:HIS80 4.3 8.3 1.0 ND1 A:HIS249 4.4 9.3 1.0 CD1 A:LEU294 4.6 13.2 1.0 N3 A:IZC1500 4.6 19.3 1.0 CE A:LYS149 4.6 11.8 1.0 CB A:ASP324 4.6 9.8 1.0 CD A:LYS149 4.7 12.2 1.0 C4 A:IZC1500 4.7 18.8 1.0 C2 A:IZC1500 4.8 20.7 1.0 CD2 A:HIS272 4.8 15.2 1.0 C5 A:IZC1500 4.9 18.6 1.0 CE1 A:HIS272 4.9 17.7 1.0 N1 A:IZC1500 5.0 20.5 1.0 ND2 A:ASN326 5.0 12.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Imidazolonepropionase Complexed with Imidazole-4- Acetic Acid Sodium Salt, A Substrate Homologue within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2601 b:13.0 occ:1.00 O B:HOH2717 2.1 16.6 1.0 NE2 B:HIS80 2.2 5.5 1.0 NE2 B:HIS82 2.2 11.1 1.0 NE2 B:HIS249 2.2 3.4 1.0 OD1 B:ASP324 2.4 8.1 1.0 CE1 B:HIS80 3.1 4.2 1.0 CD2 B:HIS80 3.1 3.5 1.0 CD2 B:HIS249 3.1 5.1 1.0 CD2 B:HIS82 3.2 10.4 1.0 CE1 B:HIS82 3.2 10.4 1.0 CE1 B:HIS249 3.2 6.2 1.0 CG B:ASP324 3.3 7.5 1.0 OD2 B:ASP324 3.6 9.0 1.0 NE2 B:HIS272 3.8 18.9 1.0 ND1 B:HIS80 4.3 4.5 1.0 ND1 B:HIS249 4.3 5.3 1.0 CG B:HIS249 4.3 6.5 1.0 ND1 B:HIS82 4.3 11.1 1.0 CG B:HIS80 4.3 4.8 1.0 CG B:HIS82 4.3 11.1 1.0 CD1 B:LEU294 4.6 7.8 1.0 CE1 B:HIS272 4.6 17.6 1.0 CE B:LYS149 4.6 7.4 1.0 CB B:ASP324 4.6 8.2 1.0 C4 B:IZC2500 4.6 15.7 1.0 CD B:LYS149 4.7 9.3 1.0 N3 B:IZC2500 4.7 14.6 1.0 C5 B:IZC2500 4.8 15.1 1.0 CD2 B:HIS272 4.8 17.2 1.0 C2 B:IZC2500 4.9 17.1 1.0 N1 B:IZC2500 4.9 14.2 1.0 ND2 B:ASN326 5.0 7.9 1.0 C6 B:IZC2500 5.0 12.9 1.0

Y.Yu, Y.H.Liang, E.Brostromer, J.M.Quan, S.Panjikar, Y.H.Dong, X.D.Su. A Catalytic Mechanism Revealed By the Crystal Structures of the Imidazolonepropionase From Bacillus Subtilis J.Biol.Chem. V. 281 36929 2006.
ISSN: ISSN 0021-9258
PubMed: 16990261
DOI: 10.1074/JBC.M607703200