Zinc in PDB 2fyv: Golgi Alpha-Mannosidase II Complex with An Amino-Salacinol Carboxylate Analog

All present enzymatic activity of Golgi Alpha-Mannosidase II Complex with An Amino-Salacinol Carboxylate Analog:
3.2.1.114;

The structure of Golgi Alpha-Mannosidase II Complex with An Amino-Salacinol Carboxylate Analog, PDB code: 2fyv was solved by D.A.Kuntz, T.Hamlet, D.R.Rose, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.60 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	68.806, 108.635, 137.384, 90.00, 90.00, 90.00
R / Rfree (%)	16.2 / 21.2

The binding sites of Zinc atom in the Golgi Alpha-Mannosidase II Complex with An Amino-Salacinol Carboxylate Analog (pdb code 2fyv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Golgi Alpha-Mannosidase II Complex with An Amino-Salacinol Carboxylate Analog, PDB code: 2fyv:

Zinc binding site 1 out of 1 in the Golgi Alpha-Mannosidase II Complex with An Amino-Salacinol Carboxylate Analog


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Golgi Alpha-Mannosidase II Complex with An Amino-Salacinol Carboxylate Analog within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2003 b:10.8 occ:1.00 NE2 A:HIS90 2.1 6.0 1.0 NE2 A:HIS471 2.1 7.6 1.0 OD1 A:ASP92 2.1 9.0 1.0 O2 A:W722000 2.1 9.7 1.0 OD2 A:ASP204 2.2 4.9 1.0 CG A:ASP92 2.9 8.6 1.0 CD2 A:HIS471 3.0 3.8 1.0 CD2 A:HIS90 3.0 5.5 1.0 CE1 A:HIS90 3.0 4.0 1.0 OD2 A:ASP92 3.1 8.9 1.0 CG A:ASP204 3.1 7.5 1.0 CE1 A:HIS471 3.1 2.2 1.0 C2 A:W722000 3.3 10.7 1.0 CB A:ASP204 3.4 6.9 1.0 C3 A:W722000 3.5 14.2 1.0 OD2 A:ASP472 4.1 6.4 1.0 ND1 A:HIS90 4.2 3.9 1.0 CG A:HIS90 4.2 5.6 1.0 CG A:HIS471 4.2 5.9 1.0 ND1 A:HIS471 4.2 6.6 1.0 OD1 A:ASP204 4.3 6.4 1.0 C1 A:W722000 4.3 12.8 1.0 N4 A:W722000 4.3 15.6 1.0 NE2 A:HIS470 4.3 9.1 1.0 CB A:ASP92 4.3 7.5 1.0 O A:HOH2731 4.4 6.0 1.0 OH A:TYR269 4.8 10.4 1.0 CA A:ASP204 4.9 7.0 1.0 CA A:ASP92 4.9 5.7 1.0 C5 A:W722000 5.0 13.8 1.0

W.Chen, D.A.Kuntz, T.Hamlet, L.Sim, D.R.Rose, B.Mario Pinto. Synthesis, Enzymatic Activity, and X-Ray Crystallography of An Unusual Class of Amino Acids. Bioorg.Med.Chem. V. 14 8332 2006.
ISSN: ISSN 0968-0896
PubMed: 17010621
DOI: 10.1016/J.BMC.2006.09.004