Zinc in PDB 2fu5: Structure of RAB8 in Complex with MSS4

The structure of Structure of RAB8 in Complex with MSS4, PDB code: 2fu5 was solved by A.Itzen, O.Pylypenko, R.S.Goody, A.Rak, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.17 / 2.00
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	40.920, 49.850, 83.480, 102.88, 97.46, 90.12
R / Rfree (%)	19.7 / 25.2

The binding sites of Zinc atom in the Structure of RAB8 in Complex with MSS4 (pdb code 2fu5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of RAB8 in Complex with MSS4, PDB code: 2fu5:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of RAB8 in Complex with MSS4


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of RAB8 in Complex with MSS4 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:24.2 occ:1.00 SG A:CYS97 2.3 25.7 1.0 SG A:CYS23 2.3 24.3 1.0 SG A:CYS26 2.3 23.9 1.0 SG A:CYS94 2.4 23.1 1.0 CB A:CYS23 3.1 22.8 1.0 CB A:CYS94 3.1 19.4 1.0 CB A:CYS26 3.2 24.7 1.0 CB A:CYS97 3.3 26.1 1.0 N A:CYS97 3.7 26.4 1.0 N A:CYS26 3.7 25.6 1.0 CA A:CYS26 4.0 24.4 1.0 CA A:CYS97 4.0 25.9 1.0 O A:HOH4374 4.3 42.7 1.0 CB A:SER28 4.5 24.2 1.0 CA A:CYS94 4.6 20.2 1.0 CA A:CYS23 4.6 23.5 1.0 CB A:ARG25 4.6 27.1 1.0 C A:ARG25 4.6 27.1 1.0 C A:CYS26 4.7 25.1 1.0 C A:CYS97 4.7 26.2 1.0 C A:ASP96 4.8 27.4 1.0 N A:GLU98 4.8 23.9 1.0 CB A:ASP96 4.8 27.7 1.0 N A:GLY27 4.8 24.7 1.0 N A:SER28 4.9 23.9 1.0

Zinc binding site 2 out of 2 in the Structure of RAB8 in Complex with MSS4


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of RAB8 in Complex with MSS4 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:24.5 occ:1.00 SG B:CYS97 2.3 25.0 1.0 SG B:CYS23 2.4 23.0 1.0 SG B:CYS94 2.4 24.8 1.0 SG B:CYS26 2.4 26.1 1.0 CB B:CYS94 3.1 22.9 1.0 CB B:CYS23 3.2 22.1 1.0 CB B:CYS26 3.3 24.8 1.0 CB B:CYS97 3.3 23.9 1.0 N B:CYS97 3.7 24.4 1.0 N B:CYS26 3.7 25.3 1.0 CA B:CYS26 4.0 25.1 1.0 CA B:CYS97 4.0 24.7 1.0 CG2 B:ILE99 4.2 29.0 1.0 CB B:SER28 4.4 24.0 1.0 CA B:CYS94 4.6 22.9 1.0 CB B:ARG25 4.6 27.2 1.0 CA B:CYS23 4.6 22.8 1.0 C B:ARG25 4.7 26.4 1.0 C B:CYS97 4.7 24.2 1.0 CB B:ASP96 4.7 25.4 1.0 C B:CYS26 4.7 24.7 1.0 N B:GLU98 4.8 23.7 1.0 C B:ASP96 4.8 25.9 1.0 N B:SER28 4.9 22.9 1.0 N B:GLY27 4.9 23.8 1.0 N B:ASP96 5.0 24.1 1.0 CA B:ARG25 5.0 27.2 1.0

A.Itzen, O.Pylypenko, R.S.Goody, K.Alexandrov, A.Rak. Nucleotide Exchange Via Local Protein Unfolding-Structure of RAB8 in Complex with MSS4 Embo J. V. 25 1445 2006.
ISSN: ISSN 0261-4189
PubMed: 16541104
DOI: 10.1038/SJ.EMBOJ.7601044