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Atomistry » Zinc » PDB 2f9y-2fnm » 2fm2 » |
Zinc in PDB 2fm2: Hcv NS3-4A Protease Domain Complexed with A Ketoamide Inhibitor, SCH446211Protein crystallography data
The structure of Hcv NS3-4A Protease Domain Complexed with A Ketoamide Inhibitor, SCH446211, PDB code: 2fm2
was solved by
M.Yi,
X.Tong,
A.Skelton,
R.Chase,
T.Chen,
A.Prongay,
S.L.Bogen,
A.K.Saksena,
F.G.Njoroge,
R.L.Veselenak,
R.B.Pyles,
N.Bourne,
B.A.Malcolm,
S.M.Lemon,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Hcv NS3-4A Protease Domain Complexed with A Ketoamide Inhibitor, SCH446211
(pdb code 2fm2). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Hcv NS3-4A Protease Domain Complexed with A Ketoamide Inhibitor, SCH446211, PDB code: 2fm2: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 2fm2Go back to Zinc Binding Sites List in 2fm2
Zinc binding site 1 out
of 2 in the Hcv NS3-4A Protease Domain Complexed with A Ketoamide Inhibitor, SCH446211
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 2fm2Go back to Zinc Binding Sites List in 2fm2
Zinc binding site 2 out
of 2 in the Hcv NS3-4A Protease Domain Complexed with A Ketoamide Inhibitor, SCH446211
Mono view Stereo pair view
Reference:
M.Yi,
X.Tong,
A.Skelton,
R.Chase,
T.Chen,
A.Prongay,
S.L.Bogen,
A.K.Saksena,
F.G.Njoroge,
R.L.Veselenak,
R.B.Pyles,
N.Bourne,
B.A.Malcolm,
S.M.Lemon.
Mutations Conferring Resistance to SCH6, A Novel Hepatitis C Virus NS3/4A Protease Inhibitor. Reduced Rna Replication Fitness and Partial Rescue By Second-Site Mutations J.Biol.Chem. V. 281 8205 2006.
Page generated: Wed Oct 16 23:48:11 2024
ISSN: ISSN 0021-9258 PubMed: 16352601 DOI: 10.1074/JBC.M510246200 |
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