Zinc in PDB 2e6l: Structure of Mouse Wrn Exonuclease Domain

The structure of Structure of Mouse Wrn Exonuclease Domain, PDB code: 2e6l was solved by Y.Cho, J.M.Choi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.57 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.047, 59.147, 60.245, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 24.4

The binding sites of Zinc atom in the Structure of Mouse Wrn Exonuclease Domain (pdb code 2e6l). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Mouse Wrn Exonuclease Domain, PDB code: 2e6l:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Mouse Wrn Exonuclease Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Mouse Wrn Exonuclease Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:26.1 occ:1.00 OE2 A:GLU78 2.0 14.5 1.0 OD1 A:ASP210 2.1 12.6 1.0 OD2 A:ASP76 2.1 16.4 1.0 O A:HOH544 2.4 22.8 1.0 O A:HOH586 2.7 21.8 1.0 CD A:GLU78 3.0 17.0 1.0 CG A:ASP210 3.1 15.2 1.0 CG A:ASP76 3.1 16.8 1.0 OE1 A:GLU78 3.3 14.3 1.0 CB A:ASP210 3.4 13.7 1.0 OD1 A:ASP76 3.4 17.7 1.0 ZN A:ZN502 3.9 40.0 1.0 O A:MET77 3.9 15.8 1.0 CE1 A:TYR206 4.0 14.6 1.0 O A:HOH606 4.2 32.6 1.0 OE1 A:GLN95 4.2 19.2 1.0 OD2 A:ASP210 4.2 15.6 1.0 OH A:TYR206 4.2 19.2 1.0 CG A:GLU78 4.3 12.9 1.0 O A:HOH549 4.4 15.5 1.0 O A:HOH607 4.5 25.8 1.0 CB A:ASP76 4.5 16.6 1.0 CZ A:TYR206 4.5 17.2 1.0 C A:MET77 4.8 16.3 1.0 O A:HOH592 4.9 28.2 1.0 CA A:ASP210 4.9 13.7 1.0 CD1 A:TYR206 5.0 15.7 1.0 N A:MET77 5.0 16.7 1.0

Zinc binding site 2 out of 2 in the Structure of Mouse Wrn Exonuclease Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Mouse Wrn Exonuclease Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:40.0 occ:1.00 OD1 A:ASP76 2.1 17.7 1.0 O A:HOH549 2.2 15.5 1.0 O A:HOH606 2.3 32.6 1.0 O A:HOH544 2.3 22.8 1.0 O A:HOH592 2.4 28.2 1.0 CG A:ASP76 3.3 16.8 1.0 OD2 A:ASP76 3.8 16.4 1.0 O A:HOH535 3.8 18.7 1.0 ZN A:ZN501 3.9 26.1 1.0 O A:VAL132 4.0 18.9 1.0 OD2 A:ASP137 4.1 19.3 1.0 O A:MET77 4.2 15.8 1.0 OD1 A:ASP137 4.4 18.9 1.0 CB A:ASP76 4.5 16.6 1.0 N A:MET77 4.5 16.7 1.0 O A:HOH632 4.5 38.2 1.0 CG A:ASP137 4.7 19.8 1.0 CA A:ASP76 4.8 15.7 1.0 O A:HOH586 4.9 21.8 1.0

Y.Cho, J.M.Choi. Probing the Roles of Active Site Residues in 3'-5' Exonuclease of Werner Syndrome Protein To Be Published.