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Zinc in PDB 2e25: The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate
Enzymatic activity of The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate
All present enzymatic activity of The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate:
3.5.2.3;
3.5.2.3;
Protein crystallography data
The structure of The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate, PDB code: 2e25
was solved by
M.Lee,
M.J.Maher,
J.M.Guss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 30.00 / 2.70 |
| Space group | P 41 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 72.610, 72.610, 176.120, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 21.8 / 25.7 |
Other elements in 2e25:
The structure of The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate also contains other interesting chemical elements:
| Fluorine | (F) | 1 atom |
Zinc Binding Sites:
The binding sites of Zinc atom in the The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate
(pdb code 2e25). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate, PDB code: 2e25:
Jump to Zinc binding site number: 1; 2;
In total 2 binding sites of Zinc where determined in the The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate, PDB code: 2e25:
Jump to Zinc binding site number: 1; 2;
Zinc binding site 1 out of 2 in 2e25
Go back to
Zinc Binding Sites List in 2e25
Zinc binding site 1 out
of 2 in the The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate within 5.0Å range:
|
Zinc binding site 2 out of 2 in 2e25
Go back to
Zinc Binding Sites List in 2e25
Zinc binding site 2 out
of 2 in the The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of The Crystal Structure of the T109S Mutant of E. Coli Dihydroorotase Complexed with An Inhibitor 5-Fluoroorotate within 5.0Å range:
|
Reference:
M.Lee,
M.J.Maher,
J.M.Guss.
Structure of the T109S Mutant of Escherichia Coli Dihydroorotase Complexed with the Inhibitor 5-Fluoroorotate: Catalytic Activity Is Reflected By the Crystal Form Acta Crystallogr.,Sect.F V. 63 154 2007.
ISSN: ESSN 1744-3091
PubMed: 17329804
DOI: 10.1107/S1744309107004009
Page generated: Wed Oct 16 22:56:10 2024
ISSN: ESSN 1744-3091
PubMed: 17329804
DOI: 10.1107/S1744309107004009
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