Zinc in PDB 2czr: Crystal Structure of Tbp-Interacting Protein (Tk-TIP26) and Implications For Its Inhibition Mechanism of the Interaction Between Tbp and Tata-Dna

The structure of Crystal Structure of Tbp-Interacting Protein (Tk-TIP26) and Implications For Its Inhibition Mechanism of the Interaction Between Tbp and Tata-Dna, PDB code: 2czr was solved by T.Yamamoto, T.Matsuda, T.Inoue, H.Matsumura, M.Morikawa, S.Kanaya, Y.Kai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.92 / 2.30
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	73.834, 73.834, 86.414, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 23.1

The binding sites of Zinc atom in the Crystal Structure of Tbp-Interacting Protein (Tk-TIP26) and Implications For Its Inhibition Mechanism of the Interaction Between Tbp and Tata-Dna (pdb code 2czr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Tbp-Interacting Protein (Tk-TIP26) and Implications For Its Inhibition Mechanism of the Interaction Between Tbp and Tata-Dna, PDB code: 2czr:

Zinc binding site 1 out of 1 in the Crystal Structure of Tbp-Interacting Protein (Tk-TIP26) and Implications For Its Inhibition Mechanism of the Interaction Between Tbp and Tata-Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Tbp-Interacting Protein (Tk-TIP26) and Implications For Its Inhibition Mechanism of the Interaction Between Tbp and Tata-Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2001 b:72.0 occ:1.00 NE2 A:HIS164 2.0 50.0 1.0 NE2 A:HIS168 2.3 61.8 1.0 SG A:CYS152 2.3 71.7 1.0 SG A:CYS149 2.3 59.6 1.0 CE1 A:HIS164 2.8 50.1 1.0 CD2 A:HIS168 3.0 60.8 1.0 CD2 A:HIS164 3.1 49.9 1.0 CB A:CYS149 3.2 59.1 1.0 CE1 A:HIS168 3.3 61.1 1.0 CB A:CYS152 3.6 70.6 1.0 N A:CYS152 3.8 71.8 1.0 ND1 A:HIS164 3.9 48.1 1.0 CG A:HIS164 4.1 48.5 1.0 CG A:HIS168 4.2 61.2 1.0 CB A:GLU151 4.2 74.4 1.0 ND1 A:HIS168 4.2 62.2 1.0 CA A:CYS152 4.3 70.0 1.0 C A:GLU151 4.6 73.0 1.0 CA A:CYS149 4.7 59.4 1.0 CA A:GLU151 4.8 73.0 1.0 N A:GLU151 4.9 71.5 1.0 O A:HIS164 5.0 49.1 1.0

T.Yamamoto, T.Matsuda, T.Inoue, H.Matsumura, M.Morikawa, S.Kanaya, Y.Kai. Crystal Structure of Tbp-Interacting Protein (Tk-TIP26) and Implications For Its Inhibition Mechanism of the Interaction Between Tbp and Tata-Dna Protein Sci. V. 15 152 2006.
ISSN: ISSN 0961-8368
PubMed: 16322571
DOI: 10.1110/PS.051788906