Atomistry » Zinc » PDB 2c6p-2ci7 » 2c9v
Atomistry »
  Zinc »
    PDB 2c6p-2ci7 »
      2c9v »

Zinc in PDB 2c9v: Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase

Enzymatic activity of Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase

All present enzymatic activity of Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase:
1.15.1.1;

Protein crystallography data

The structure of Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase, PDB code: 2c9v was solved by R.W.Strange, S.V.Antonyuk, M.A.Hough, P.A.Doucette, J.S.Valentine, S.S.Hasnain, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.00 / 1.07
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 38.605, 67.368, 52.532, 90.00, 106.54, 90.00
R / Rfree (%) 13.1 / 15.8

Other elements in 2c9v:

The structure of Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase also contains other interesting chemical elements:

Copper (Cu) 4 atoms
Sodium (Na) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase (pdb code 2c9v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase, PDB code: 2c9v:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2c9v

Go back to Zinc Binding Sites List in 2c9v
Zinc binding site 1 out of 2 in the Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn155

b:7.8
occ:1.00
OD1 A:ASP83 1.9 7.4 1.0
ND1 A:HIS71 2.0 8.0 1.0
ND1 A:HIS63 2.0 7.8 1.0
ND1 A:HIS80 2.0 7.6 1.0
CG A:ASP83 2.7 8.0 1.0
OD2 A:ASP83 2.9 8.0 1.0
CE1 A:HIS71 2.9 7.9 1.0
CE1 A:HIS80 2.9 8.3 1.0
CE1 A:HIS63 3.0 9.1 1.0
CG A:HIS63 3.1 8.2 1.0
CG A:HIS80 3.1 7.5 1.0
CG A:HIS71 3.1 8.1 1.0
CB A:HIS63 3.5 8.7 1.0
CB A:HIS80 3.6 7.2 1.0
CB A:HIS71 3.7 8.5 1.0
O A:LYS136 3.9 10.8 1.0
CA A:HIS71 4.0 8.6 1.0
NE2 A:HIS80 4.0 8.8 1.0
NE2 A:HIS71 4.1 7.6 1.0
NE2 A:HIS63 4.1 10.2 1.0
CD2 A:HIS80 4.1 8.4 1.0
CD2 A:HIS63 4.2 9.9 1.0
CB A:ASP83 4.2 8.1 1.0
CD2 A:HIS71 4.2 8.9 1.0
CA A:ASP83 4.7 8.1 1.0
N A:HIS80 4.7 7.8 1.0
N A:GLY72 4.8 8.7 1.0
CA A:HIS80 4.8 7.4 1.0
CD2 A:HIS46 4.9 8.8 1.0
C A:HIS71 4.9 8.8 1.0
O A:HOH2128 4.9 14.4 1.0
C A:LYS136 4.9 10.4 1.0
N A:HIS71 5.0 9.4 1.0
N A:ASP83 5.0 7.5 1.0
CA A:HIS63 5.0 7.6 1.0

Zinc binding site 2 out of 2 in 2c9v

Go back to Zinc Binding Sites List in 2c9v
Zinc binding site 2 out of 2 in the Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Atomic Resolution Structure of Cu-Zn Human Superoxide Dismutase within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn155

b:8.1
occ:1.00
OD1 F:ASP83 1.9 7.7 1.0
ND1 F:HIS63 2.0 7.8 1.0
ND1 F:HIS80 2.0 7.8 1.0
ND1 F:HIS71 2.0 8.3 1.0
CG F:ASP83 2.7 8.7 1.0
OD2 F:ASP83 2.8 8.5 1.0
CE1 F:HIS71 2.9 8.1 1.0
CE1 F:HIS80 2.9 8.6 1.0
CE1 F:HIS63 3.0 9.0 1.0
CG F:HIS63 3.0 8.3 1.0
CG F:HIS80 3.1 7.7 1.0
CG F:HIS71 3.2 8.6 1.0
CB F:HIS63 3.4 8.9 1.0
CB F:HIS80 3.5 8.8 1.0
CB F:HIS71 3.7 9.1 1.0
O F:LYS136 3.9 11.9 1.0
CA F:HIS71 4.0 9.7 1.0
NE2 F:HIS80 4.0 8.9 1.0
NE2 F:HIS63 4.1 10.1 1.0
NE2 F:HIS71 4.1 8.1 1.0
CD2 F:HIS80 4.1 8.7 1.0
CD2 F:HIS63 4.1 9.9 1.0
CB F:ASP83 4.2 7.9 1.0
CD2 F:HIS71 4.2 9.3 1.0
CA F:ASP83 4.7 8.3 1.0
N F:HIS80 4.7 8.2 1.0
CA F:HIS80 4.8 8.0 1.0
N F:GLY72 4.8 9.0 1.0
O F:HOH2271 4.9 15.3 1.0
CD2 F:HIS46 4.9 8.7 1.0
N F:ASP83 4.9 7.3 1.0
C F:LYS136 4.9 11.5 1.0
C F:HIS71 5.0 8.8 1.0
CA F:HIS63 5.0 8.1 1.0

Reference:

R.W.Strange, S.V.Antonyuk, M.A.Hough, P.A.Doucette, J.S.Valentine, S.S.Hasnain. Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and As-Isolated Wild-Type Enzymes. J.Mol.Biol. V. 356 1152 2006.
ISSN: ISSN 0022-2836
PubMed: 16406071
DOI: 10.1016/J.JMB.2005.11.081
Page generated: Wed Dec 16 03:19:06 2020

Last articles

Ca in 5X9A
Ca in 5XDW
Ca in 5XDV
Ca in 5XDU
Ca in 5XDT
Ca in 5XCV
Ca in 5XAU
Ca in 5XAG
Ca in 5XAF
Ca in 5XA8
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy