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Atomistry » Zinc » PDB 2a25-2aer » 2a4r | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 2a25-2aer » 2a4r » |
Zinc in PDB 2a4r: Hcv NS3 Protease Domain with A Ketoamide Inhibitor Covalently Bound.Protein crystallography data
The structure of Hcv NS3 Protease Domain with A Ketoamide Inhibitor Covalently Bound., PDB code: 2a4r
was solved by
S.Bogen,
A.K.Saksena,
A.Arasappan,
H.Gu,
F.G.Njoroge,
V.Girijavallabhan,
J.Pichardo,
N.Butkiewicz,
A.Prongay,
V.Madison,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Hcv NS3 Protease Domain with A Ketoamide Inhibitor Covalently Bound.
(pdb code 2a4r). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Hcv NS3 Protease Domain with A Ketoamide Inhibitor Covalently Bound., PDB code: 2a4r: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 2a4rGo back to Zinc Binding Sites List in 2a4r
Zinc binding site 1 out
of 2 in the Hcv NS3 Protease Domain with A Ketoamide Inhibitor Covalently Bound.
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 2a4rGo back to Zinc Binding Sites List in 2a4r
Zinc binding site 2 out
of 2 in the Hcv NS3 Protease Domain with A Ketoamide Inhibitor Covalently Bound.
Mono view Stereo pair view
Reference:
S.Bogen,
A.K.Saksena,
A.Arasappan,
H.Gu,
F.G.Njoroge,
V.Girijavallabhan,
J.Pichardo,
N.Butkiewicz,
A.Prongay,
V.Madison.
Hepatitis C Virus NS3-4A Serine Protease Inhibitors: Use of A P2-P1 Cyclopropyl Alanine Combination For Improved Potency. Bioorg.Med.Chem.Lett. V. 15 4515 2005.
Page generated: Wed Oct 16 21:30:04 2024
ISSN: ISSN 0960-894X PubMed: 16112862 DOI: 10.1016/J.BMCL.2005.07.009 |
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