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Atomistry » Zinc » PDB 1zs0-2a21 » 1zxc | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 1zs0-2a21 » 1zxc » |
Zinc in PDB 1zxc: Crystal Structure of Catalytic Domain of Tnf-Alpha Converting Enzyme (Tace) with InhibitorEnzymatic activity of Crystal Structure of Catalytic Domain of Tnf-Alpha Converting Enzyme (Tace) with Inhibitor
All present enzymatic activity of Crystal Structure of Catalytic Domain of Tnf-Alpha Converting Enzyme (Tace) with Inhibitor:
3.4.24.86; Protein crystallography data
The structure of Crystal Structure of Catalytic Domain of Tnf-Alpha Converting Enzyme (Tace) with Inhibitor, PDB code: 1zxc
was solved by
J.I.Levin,
J.M.Chen,
L.M.Laakso,
M.Du,
J.Schmid,
W.Xu,
T.Cummons,
J.Xu,
Y.Zhang,
G.Jin,
R.Cowling,
D.Barone,
J.S.Skotnicki,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Catalytic Domain of Tnf-Alpha Converting Enzyme (Tace) with Inhibitor
(pdb code 1zxc). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Catalytic Domain of Tnf-Alpha Converting Enzyme (Tace) with Inhibitor, PDB code: 1zxc: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 1zxcGo back to Zinc Binding Sites List in 1zxc
Zinc binding site 1 out
of 2 in the Crystal Structure of Catalytic Domain of Tnf-Alpha Converting Enzyme (Tace) with Inhibitor
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 1zxcGo back to Zinc Binding Sites List in 1zxc
Zinc binding site 2 out
of 2 in the Crystal Structure of Catalytic Domain of Tnf-Alpha Converting Enzyme (Tace) with Inhibitor
Mono view Stereo pair view
Reference:
J.I.Levin,
J.M.Chen,
L.M.Laakso,
M.Du,
X.Du,
A.M.Venkatesan,
V.Sandanayaka,
A.Zask,
J.Xu,
W.Xu,
Y.Zhang,
J.S.Skotnicki.
Acetylenic Tace Inhibitors. Part 2: Sar of Six-Membered Cyclic Sulfonamide Hydroxamates. Bioorg.Med.Chem.Lett. V. 15 4345 2005.
Page generated: Wed Oct 16 21:24:19 2024
ISSN: ISSN 0960-894X PubMed: 16084720 DOI: 10.1016/J.BMCL.2005.06.072 |
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