Zinc in PDB 1yp1: Crystal Structure of A Non-Hemorrhagic Fibrin(Ogen)Olytic Metalloproteinase From Venom of Agkistrodon Acutus

The structure of Crystal Structure of A Non-Hemorrhagic Fibrin(Ogen)Olytic Metalloproteinase From Venom of Agkistrodon Acutus, PDB code: 1yp1 was solved by Z.Lou, J.Hou, J.Chen, X.Liang, P.Qiu, Y.Liu, M.Li, Z.Rao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.90
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	80.565, 80.565, 66.769, 90.00, 90.00, 120.00
R / Rfree (%)	21.7 / 23.4

The binding sites of Zinc atom in the Crystal Structure of A Non-Hemorrhagic Fibrin(Ogen)Olytic Metalloproteinase From Venom of Agkistrodon Acutus (pdb code 1yp1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of A Non-Hemorrhagic Fibrin(Ogen)Olytic Metalloproteinase From Venom of Agkistrodon Acutus, PDB code: 1yp1:

Zinc binding site 1 out of 1 in the Crystal Structure of A Non-Hemorrhagic Fibrin(Ogen)Olytic Metalloproteinase From Venom of Agkistrodon Acutus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of A Non-Hemorrhagic Fibrin(Ogen)Olytic Metalloproteinase From Venom of Agkistrodon Acutus within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn999 b:30.5 occ:1.00 NE2 A:HIS152 2.0 29.1 1.0 NE2 A:HIS142 2.1 24.2 1.0 NE2 A:HIS146 2.2 28.8 1.0 O B:HOH4 2.3 31.4 1.0 O B:LEU3 2.6 59.2 1.0 CD2 A:HIS152 3.0 28.5 1.0 CE1 A:HIS152 3.0 30.9 1.0 CD2 A:HIS146 3.0 29.1 1.0 CD2 A:HIS142 3.1 25.8 1.0 CE1 A:HIS142 3.2 26.6 1.0 CE1 A:HIS146 3.3 27.9 1.0 C B:LEU3 3.7 52.5 1.0 ND1 A:HIS152 4.1 31.1 1.0 CG A:HIS152 4.2 31.3 1.0 CG A:HIS142 4.2 24.0 1.0 ND1 A:HIS142 4.2 27.9 1.0 CG A:HIS146 4.3 27.9 1.0 OXT B:LEU3 4.3 59.7 1.0 ND1 A:HIS146 4.3 28.6 1.0 CA B:LEU3 4.7 50.8 1.0 CB B:LEU3 4.7 44.7 1.0 CE A:MET165 4.8 26.6 1.0 O A:PRO167 4.9 33.8 1.0 OE2 A:GLU143 5.0 29.2 1.0

Z.Lou, J.Hou, X.Liang, J.Chen, P.Qiu, Y.Liu, M.Li, Z.Rao, G.Yan. Crystal Structure of A Non-Hemorrhagic Fibrin(Ogen)Olytic Metalloproteinase Complexed with A Novel Natural Tri-Peptide Inhibitor From Venom of Agkistrodon Acutus J.Struct.Biol. V. 152 195 2005.
ISSN: ISSN 1047-8477
PubMed: 16330227
DOI: 10.1016/J.JSB.2005.09.006