Zinc in PDB 1ynn: Taq Rna Polymerase-Rifampicin Complex

All present enzymatic activity of Taq Rna Polymerase-Rifampicin Complex:
2.7.7.6;

The structure of Taq Rna Polymerase-Rifampicin Complex, PDB code: 1ynn was solved by E.A.Campbell, O.Pavlova, N.Zenkin, F.Leon, H.Irschik, R.Jansen, K.Severinov, S.A.Darst, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 3.30
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	200.760, 200.760, 292.938, 90.00, 90.00, 90.00
R / Rfree (%)	27.1 / 33.1

The binding sites of Zinc atom in the Taq Rna Polymerase-Rifampicin Complex (pdb code 1ynn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Taq Rna Polymerase-Rifampicin Complex, PDB code: 1ynn:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Taq Rna Polymerase-Rifampicin Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Taq Rna Polymerase-Rifampicin Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1525 b:90.3 occ:1.00 N D:ALA59 2.6 0.4 1.0 O D:CYS76 2.8 0.8 1.0 CB D:CYS58 3.0 0.9 1.0 C D:CYS58 3.1 0.1 1.0 CB D:ALA59 3.2 0.6 1.0 CA D:ALA59 3.4 0.7 1.0 CA D:CYS58 3.5 0.0 1.0 SG D:CYS58 3.6 0.9 1.0 N D:CYS60 3.7 1.0 1.0 C D:CYS76 3.9 0.9 1.0 CB D:CYS76 3.9 1.0 1.0 O D:CYS58 4.0 0.2 1.0 C D:ALA59 4.1 0.7 1.0 SG D:CYS76 4.2 0.7 1.0 CG2 D:VAL78 4.3 95.8 1.0 CA D:CYS76 4.5 0.9 1.0 N D:CYS58 4.9 0.6 1.0 CA D:CYS60 4.9 0.3 1.0 N D:GLY77 4.9 0.6 1.0 CB D:CYS73 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Taq Rna Polymerase-Rifampicin Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Taq Rna Polymerase-Rifampicin Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1526 b:52.6 occ:1.00 SG D:CYS1112 1.9 40.4 1.0 SG D:CYS1194 2.1 36.4 1.0 SG D:CYS1204 2.6 34.4 1.0 SG D:CYS1201 2.7 36.0 1.0 CB D:CYS1112 3.2 40.2 1.0 CB D:CYS1194 3.2 37.2 1.0 CB D:CYS1204 3.5 33.9 1.0 CA D:CYS1194 3.6 37.3 1.0 CB D:CYS1201 3.7 36.3 1.0 NH1 D:ARG1189 3.9 35.0 1.0 N D:CYS1112 4.0 40.1 1.0 N D:GLN1195 4.1 40.0 1.0 CA D:CYS1112 4.2 40.2 1.0 C D:CYS1194 4.4 38.5 1.0 N D:CYS1204 4.5 34.6 1.0 CA D:CYS1204 4.6 34.1 1.0 N D:CYS1201 4.6 36.8 1.0 CA D:CYS1201 4.7 36.3 1.0 N D:CYS1194 4.7 36.2 1.0 O D:THR1193 5.0 35.2 1.0 C D:CYS1112 5.0 40.2 1.0 CG2 D:THR1114 5.0 39.5 1.0 O D:CYS1201 5.0 35.6 1.0

E.A.Campbell, O.Pavlova, N.Zenkin, F.Leon, H.Irschik, R.Jansen, K.Severinov, S.A.Darst. Structural, Functional, and Genetic Analysis of Sorangicin Inhibition of Bacterial Rna Polymerase Embo J. V. 24 674 2005.
ISSN: ISSN 0261-4189
PubMed: 15692574
DOI: 10.1038/SJ.EMBOJ.7600499