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Atomistry » Zinc » PDB 1xm6-1xug » 1xq0 » |
Zinc in PDB 1xq0: Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-TriazoleEnzymatic activity of Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-Triazole
All present enzymatic activity of Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-Triazole:
4.2.1.1; Protein crystallography data
The structure of Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-Triazole, PDB code: 1xq0
was solved by
M.D.Lloyd,
N.Thiyagarajan,
Y.T.Ho,
L.W.L.Woo,
O.B.Sutcliffe,
A.Purohit,
M.J.Reed,
K.R.Acharya,
B.V.L.Potter,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1xq0:
The structure of Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-Triazole also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-Triazole
(pdb code 1xq0). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-Triazole, PDB code: 1xq0: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 1xq0Go back to Zinc Binding Sites List in 1xq0
Zinc binding site 1 out
of 2 in the Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-Triazole
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 1xq0Go back to Zinc Binding Sites List in 1xq0
Zinc binding site 2 out
of 2 in the Structure of Human Carbonic Anhydrase II with 4-[(3-Bromo-4- O-Sulfamoylbenzyl)(4-Cyanophenyl)Amino]-4H-[1,2,4]-Triazole
Mono view Stereo pair view
Reference:
M.D.Lloyd,
N.Thiyagarajan,
Y.T.Ho,
L.W.L.Woo,
O.B.Sutcliffe,
A.Purohit,
M.J.Reed,
K.R.Acharya,
B.V.L.Potter.
First Crystal Structures of Human Carbonic Anhydrase II in Complex with Dual Aromatase-Steroid Sulfatase Inhibitors(,) Biochemistry V. 44 6858 2005.
Page generated: Wed Dec 16 03:13:03 2020
ISSN: ISSN 0006-2960 PubMed: 15865431 DOI: 10.1021/BI047692E |
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