Zinc in PDB 1xkf: Crystal Structure of Hypoxic Response Protein I (Hrpi) with Two Coordinated Zinc Ions

The structure of Crystal Structure of Hypoxic Response Protein I (Hrpi) with Two Coordinated Zinc Ions, PDB code: 1xkf was solved by M.L.Sharpe, E.N.Baker, J.S.Lott, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.47 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.650, 50.940, 129.190, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 23.5

The binding sites of Zinc atom in the Crystal Structure of Hypoxic Response Protein I (Hrpi) with Two Coordinated Zinc Ions (pdb code 1xkf). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Hypoxic Response Protein I (Hrpi) with Two Coordinated Zinc Ions, PDB code: 1xkf:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Hypoxic Response Protein I (Hrpi) with Two Coordinated Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Hypoxic Response Protein I (Hrpi) with Two Coordinated Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:25.6 occ:1.00 O A:HOH1077 2.1 16.5 1.0 O B:HOH134 2.1 16.0 1.0 NE2 B:HIS122 2.1 24.0 1.0 NE2 A:HIS122 2.1 20.2 1.0 O A:HOH1004 2.2 19.2 1.0 O B:HOH200 2.3 19.7 1.0 CE1 B:HIS122 3.0 25.6 1.0 CE1 A:HIS122 3.0 23.2 1.0 CD2 A:HIS122 3.1 22.5 1.0 CD2 B:HIS122 3.2 23.3 1.0 O B:HOH138 3.8 23.5 1.0 O A:ASP6 4.0 26.3 1.0 O B:HOH128 4.0 18.3 1.0 ND1 B:HIS122 4.1 23.8 1.0 ND1 A:HIS122 4.2 21.2 1.0 O B:ILE7 4.2 17.6 1.0 CG A:HIS122 4.2 22.2 1.0 CG B:HIS122 4.3 24.6 1.0 O B:ASP6 4.3 20.6 1.0 O A:ILE7 4.7 17.8 1.0 O A:HOH1009 4.7 19.6 1.0 CA B:ILE7 4.8 17.9 1.0 C B:ILE7 4.8 17.7 1.0 CA A:ILE7 4.9 19.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Hypoxic Response Protein I (Hrpi) with Two Coordinated Zinc Ions


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Hypoxic Response Protein I (Hrpi) with Two Coordinated Zinc Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:35.6 occ:1.00 NE2 A:HIS97 2.0 23.1 1.0 O A:HOH1041 2.1 32.9 1.0 O A:HOH1079 2.2 29.2 1.0 O A:HOH1078 2.4 26.1 1.0 CE1 A:HIS97 2.8 24.2 1.0 CD2 A:HIS97 3.1 23.9 1.0 ND1 A:HIS97 4.0 25.2 1.0 CG A:HIS97 4.1 25.9 1.0 O A:ILE78 4.3 32.6 1.0 OE2 A:GLU96 4.4 36.6 1.0 O A:HOH1103 4.5 38.1 1.0 CB A:TYR79 4.6 23.8 1.0

M.L.Sharpe, C.Gao, S.L.Kendall, E.N.Baker, J.S.Lott. The Structure and Unusual Protein Chemistry of Hypoxic Response Protein 1, A Latency Antigen and Highly Expressed Member of the Dosr Regulon in Mycobacterium Tuberculosis J.Mol.Biol. V. 383 822 2008.
ISSN: ISSN 0022-2836
PubMed: 18640126
DOI: 10.1016/J.JMB.2008.07.001