Zinc in PDB 1vsl: Asv Integrase Core Domain D64N Mutation with Zinc Cation

The structure of Asv Integrase Core Domain D64N Mutation with Zinc Cation, PDB code: 1vsl was solved by J.Lubkowski, F.Yang, J.Alexandratos, A.Wlodawer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.20
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	67.159, 67.159, 79.651, 90.00, 90.00, 90.00
R / Rfree (%)	15.6 / 24.4

The binding sites of Zinc atom in the Asv Integrase Core Domain D64N Mutation with Zinc Cation (pdb code 1vsl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Asv Integrase Core Domain D64N Mutation with Zinc Cation, PDB code: 1vsl:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Asv Integrase Core Domain D64N Mutation with Zinc Cation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Asv Integrase Core Domain D64N Mutation with Zinc Cation within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn200 b:64.3 occ:1.00 OD2 A:ASP121 2.1 44.3 1.0 O A:HOH210 2.6 22.4 1.0 CG A:ASP121 3.0 35.1 1.0 OD1 A:ASP121 3.2 40.5 1.0 O A:HOH215 4.2 30.6 1.0 CB A:ASP121 4.4 35.2 1.0 CG A:PRO147 4.7 0.9 1.0 O A:HOH276 4.8 59.6 1.0 CB A:PRO147 4.9 0.6 1.0 CE2 A:PHE126 4.9 24.6 1.0 CA A:GLY123 4.9 42.7 1.0

Zinc binding site 2 out of 2 in the Asv Integrase Core Domain D64N Mutation with Zinc Cation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Asv Integrase Core Domain D64N Mutation with Zinc Cation within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:58.2 occ:1.00 O A:HOH206 2.4 21.5 1.0 ND1 A:HIS103 2.6 21.4 1.0 O A:HOH238 2.7 34.4 1.0 CG A:HIS103 3.4 16.9 1.0 CB A:HIS103 3.6 11.0 1.0 CE1 A:HIS103 3.7 21.1 1.0 O A:HOH261 3.8 54.5 1.0 O A:HOH236 4.0 46.7 1.0 ND1 A:HIS93 4.1 18.9 1.0 CE1 A:HIS93 4.4 18.7 1.0 CD2 A:HIS103 4.7 20.8 1.0 O A:HOH220 4.7 33.7 1.0 NE2 A:HIS103 4.7 22.3 1.0 O A:HOH234 4.8 51.5 1.0

J.Lubkowski, F.Yang, J.Alexandratos, G.Merkel, R.A.Katz, K.Gravuer, A.M.Skalka, A.Wlodawer. Structural Basis For Inactivating Mutations and pH-Dependent Activity of Avian Sarcoma Virus Integrase. J.Biol.Chem. V. 273 32685 1998.
ISSN: ISSN 0021-9258
PubMed: 9830010
DOI: 10.1074/JBC.273.49.32685