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Zinc in PDB 1vfn: Purine Nucleoside Phosphorylase

Enzymatic activity of Purine Nucleoside Phosphorylase

All present enzymatic activity of Purine Nucleoside Phosphorylase:
2.4.2.1;

Protein crystallography data

The structure of Purine Nucleoside Phosphorylase, PDB code: 1vfn was solved by G.Koellner, A.Bzowska, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.15
Space group P 21 3
Cell size a, b, c (Å), α, β, γ (°) 94.110, 94.110, 94.110, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1vfn:

The structure of Purine Nucleoside Phosphorylase also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Purine Nucleoside Phosphorylase (pdb code 1vfn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Purine Nucleoside Phosphorylase, PDB code: 1vfn:

Zinc binding site 1 out of 1 in 1vfn

Go back to Zinc Binding Sites List in 1vfn
Zinc binding site 1 out of 1 in the Purine Nucleoside Phosphorylase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Purine Nucleoside Phosphorylase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn434

b:28.9
occ:0.33
NE2 A:HIS20 2.2 17.7 1.0
O A:HOH433 2.8 32.7 0.3
CD2 A:HIS20 3.0 17.4 1.0
O A:HOH432 3.1 27.5 0.3
CE1 A:HIS20 3.4 17.6 1.0
CG A:HIS20 4.2 16.9 1.0
O A:HOH357 4.3 26.0 1.0
ND1 A:HIS20 4.4 18.2 1.0
O A:HOH325 4.6 50.6 1.0
NE1 A:TRP16 4.8 15.6 1.0
CZ2 A:TRP16 4.9 16.4 1.0

Reference:

G.Koellner, M.Luic, D.Shugar, W.Saenger, A.Bzowska. Crystal Structure of Calf Spleen Purine Nucleoside Phosphorylase in A Complex with Hypoxanthine at 2.15 A Resolution. J.Mol.Biol. V. 265 202 1997.
ISSN: ISSN 0022-2836
PubMed: 9020983
DOI: 10.1006/JMBI.1996.0730
Page generated: Wed Oct 16 19:48:51 2024

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