Zinc in PDB 1uxb: Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose

The structure of Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose, PDB code: 1uxb was solved by W.P.Burmeister, D.Guilligay, S.Cusack, G.Wadell, N.Arnberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	74.54 / 1.75
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	60.700, 68.700, 74.700, 90.00, 94.90, 90.00
R / Rfree (%)	17.5 / 21

The binding sites of Zinc atom in the Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose (pdb code 1uxb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose, PDB code: 1uxb:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1367 b:33.0 occ:1.00 OE2 A:GLU351 1.9 33.6 1.0 NE2 A:HIS231 1.9 24.2 1.0 O A:HOH2179 2.1 53.3 1.0 O A:ACT1369 2.1 41.2 1.0 O A:HOH2177 2.3 25.0 1.0 OXT A:ACT1370 2.5 46.9 1.0 CE1 A:HIS231 2.8 24.7 1.0 CD A:GLU351 2.9 26.8 1.0 CD2 A:HIS231 3.0 24.6 1.0 C A:ACT1369 3.0 45.4 1.0 OXT A:ACT1369 3.3 34.4 1.0 C A:ACT1370 3.4 51.7 1.0 CG A:GLU351 3.4 21.4 1.0 ND1 A:HIS231 4.0 24.2 1.0 OE1 A:GLU351 4.0 32.1 1.0 O A:ACT1370 4.0 51.8 1.0 O A:VAL225 4.1 21.2 1.0 CG A:HIS231 4.1 21.4 1.0 CH3 A:ACT1370 4.3 49.9 1.0 CE B:LYS300 4.4 39.3 1.0 CH3 A:ACT1369 4.4 43.2 1.0 O A:VAL226 4.5 30.6 1.0 CA A:VAL226 4.5 23.6 1.0 CB A:GLU351 4.7 14.9 1.0 NZ B:LYS300 4.8 35.6 1.0 C A:VAL226 4.8 22.2 1.0 CD1 A:ILE232 4.8 27.4 1.0

Zinc binding site 2 out of 3 in the Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1367 b:31.3 occ:1.00 O B:HOH2175 1.5 21.7 1.0 NE2 B:HIS231 2.2 26.9 1.0 O B:HOH2174 2.2 23.8 1.0 OE2 B:GLU351 2.2 32.5 1.0 O B:HOH2173 2.5 41.8 1.0 CE1 B:HIS231 3.1 27.0 1.0 CD B:GLU351 3.1 34.0 1.0 CD2 B:HIS231 3.2 24.7 1.0 CG B:GLU351 3.7 32.9 1.0 O C:HOH2135 3.7 45.3 1.0 O B:HOH2154 4.1 36.0 1.0 OE1 B:GLU351 4.1 36.1 1.0 CE C:LYS300 4.2 37.9 1.0 O B:VAL225 4.2 16.9 1.0 ND1 B:HIS231 4.2 22.9 1.0 CG B:HIS231 4.3 18.8 1.0 O B:VAL226 4.4 23.3 1.0 NZ C:LYS300 4.5 32.3 1.0 CA B:VAL226 4.5 25.0 1.0 C B:VAL226 4.8 21.3 1.0 CD C:LYS300 4.9 36.9 1.0

Zinc binding site 3 out of 3 in the Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Adenovirus AD19P Fibre Head in Complex with Sialyl-Lactose within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1366 b:27.8 occ:1.00 OXT C:ACT1369 1.8 42.7 1.0 O C:ACT1369 2.0 33.0 1.0 NE2 C:HIS231 2.1 16.6 1.0 C C:ACT1369 2.1 39.8 1.0 CD2 C:HIS231 2.9 18.1 1.0 CE1 C:HIS231 3.1 18.3 1.0 O C:HOH2202 3.3 50.0 1.0 CH3 C:ACT1369 3.6 46.2 1.0 CG C:HIS231 4.1 14.9 1.0 ND1 C:HIS231 4.2 16.1 1.0 CD1 C:ILE232 4.5 25.4 1.0 OE2 C:GLU351 4.6 21.0 1.0 CG1 C:ILE232 4.6 17.4 1.0

W.P.Burmeister, D.Guilligay, S.Cusack, G.Wadell, N.Arnberg. Crystal Structure of Species D Adenovirus Fiber Knobs and Their Sialic Acid Binding Sites J.Virol. V. 78 7727 2004.
ISSN: ISSN 0022-538X
PubMed: 15220447
DOI: 10.1128/JVI.78.14.7727-7736.2004