Zinc in PDB 1uxa: Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose

The structure of Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose, PDB code: 1uxa was solved by W.P.Burmeister, D.Guilligay, S.Cusack, G.Wadell, N.Arnberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.18 / 1.5
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	60.700, 68.700, 74.700, 90.00, 94.90, 90.00
R / Rfree (%)	18 / 20.5

The binding sites of Zinc atom in the Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose (pdb code 1uxa). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose, PDB code: 1uxa:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1367 b:27.6 occ:1.00 OXT C:ACT1369 1.3 9.7 1.0 C C:ACT1369 1.8 27.2 1.0 O C:ACT1369 2.0 31.5 1.0 NE2 C:HIS231 2.1 15.8 1.0 O A:HOH2167 2.4 31.1 1.0 CD2 C:HIS231 2.8 17.8 1.0 CE1 C:HIS231 3.2 19.6 1.0 CH3 C:ACT1369 3.3 36.0 1.0 CG C:HIS231 4.0 16.2 1.0 ND1 C:HIS231 4.2 13.6 1.0 CD1 C:ILE232 4.2 22.1 1.0 CG1 C:ILE232 4.3 16.9 1.0 O C:HOH2061 4.8 44.4 1.0

Zinc binding site 2 out of 3 in the Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1367 b:20.8 occ:1.00 OE2 A:GLU351 1.8 24.5 1.0 NE2 A:HIS231 2.0 22.8 1.0 O B:ACT1369 2.1 21.1 1.0 O B:HOH2162 2.1 22.6 1.0 O B:HOH2163 2.2 22.6 1.0 CE1 A:HIS231 2.9 16.9 1.0 CD A:GLU351 2.9 24.2 1.0 C B:ACT1369 3.0 33.8 1.0 CD2 A:HIS231 3.0 17.5 1.0 OXT B:ACT1369 3.4 25.3 1.0 CG A:GLU351 3.4 16.0 1.0 O B:HOH2081 4.0 27.6 1.0 OE1 A:GLU351 4.0 20.1 1.0 ND1 A:HIS231 4.1 18.5 1.0 CG A:HIS231 4.1 15.7 1.0 O A:VAL225 4.1 15.8 1.0 O A:HOH2021 4.2 42.5 1.0 CH3 B:ACT1369 4.4 30.9 1.0 CE B:LYS300 4.5 21.4 1.0 NZ B:LYS300 4.6 25.8 1.0 CA A:VAL226 4.6 18.8 1.0 O A:VAL226 4.6 25.1 1.0 CB A:GLU351 4.8 16.2 1.0 CD1 A:ILE232 4.9 20.6 1.0 C A:VAL226 5.0 19.9 1.0

Zinc binding site 3 out of 3 in the Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Adenovirus AD37 Fibre Head in Complex with Sialyl-Lactose within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1367 b:23.6 occ:1.00 OE2 B:GLU351 2.0 30.2 1.0 NE2 B:HIS231 2.0 20.1 1.0 O C:HOH2191 2.1 20.7 1.0 O C:HOH2192 2.4 36.2 1.0 CE1 B:HIS231 2.9 19.8 1.0 CD B:GLU351 3.0 22.0 1.0 CD2 B:HIS231 3.1 20.1 1.0 O C:HOH2115 3.7 41.9 1.0 CG B:GLU351 3.7 20.8 1.0 OE1 B:GLU351 4.0 22.0 1.0 O B:HOH2143 4.0 26.1 1.0 ND1 B:HIS231 4.1 17.4 1.0 O B:VAL225 4.1 18.3 1.0 CG B:HIS231 4.2 17.6 1.0 CE C:LYS300 4.3 26.2 1.0 O B:VAL226 4.3 21.4 1.0 CA B:VAL226 4.5 21.9 1.0 NZ C:LYS300 4.6 26.3 1.0 C B:VAL226 4.8 20.9 1.0 O C:HOH2107 5.0 17.1 1.0 CB B:GLU351 5.0 15.9 1.0 CD1 B:ILE232 5.0 24.0 1.0

W.P.Burmeister, D.Guilligay, S.Cusack, G.Wadell, N.Arnberg. Crystal Structure of Species D Adenovirus Fiber Knobs and Their Sialic Acid Binding Sites J.Virol. V. 78 7727 2004.
ISSN: ISSN 0022-538X
PubMed: 15220447
DOI: 10.1128/JVI.78.14.7727-7736.2004