Zinc in PDB 1ty2: Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J)

The structure of Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J), PDB code: 1ty2 was solved by H.M.Baker, T.Proft, P.D.Webb, V.L.Arcus, J.D.Fraser, E.N.Baker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	167.330, 46.330, 72.220, 90.00, 90.54, 90.00
R / Rfree (%)	21.8 / 24.9

The binding sites of Zinc atom in the Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J) (pdb code 1ty2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J), PDB code: 1ty2:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn700 b:51.5 occ:1.00 O A:HOH735 1.7 34.8 1.0 OD2 A:ASP205 2.1 30.8 1.0 NE2 A:HIS203 2.2 34.1 1.0 CG A:ASP205 2.9 29.9 1.0 CE1 A:HIS203 3.1 32.9 1.0 OD1 A:ASP205 3.1 30.7 1.0 CD2 A:HIS203 3.2 33.0 1.0 NE2 A:HIS169 3.3 56.7 1.0 CD2 A:HIS169 4.1 55.7 1.0 ND1 A:HIS203 4.2 34.9 1.0 CE1 A:HIS169 4.3 56.2 1.0 CG A:HIS203 4.3 34.8 1.0 CB A:ASP205 4.3 28.1 1.0 CB A:ALA163 4.5 36.7 1.0 ND2 A:ASN107 4.6 38.9 1.0 ND2 C:ASN96 4.9 74.9 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn701 b:55.4 occ:1.00 OD2 B:ASP205 2.0 31.6 1.0 NE2 B:HIS203 2.3 29.2 1.0 NE2 B:HIS169 2.5 42.9 1.0 CE1 B:HIS203 3.1 27.2 1.0 CG B:ASP205 3.2 27.4 1.0 CD2 B:HIS203 3.3 27.3 1.0 CE1 B:HIS169 3.4 45.6 1.0 CD2 B:HIS169 3.6 44.4 1.0 OD1 B:ASP205 3.8 26.4 1.0 ND1 B:HIS203 4.2 27.1 1.0 CB B:ASP205 4.3 25.5 1.0 CG B:HIS203 4.4 28.8 1.0 CB B:ALA163 4.6 27.2 1.0 ND1 B:HIS169 4.6 45.6 1.0 CG B:HIS169 4.7 44.4 1.0 OH B:TYR207 5.0 41.0 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the Streptococcal Pyrogenic Exotoxin J (Spe-J) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn702 b:50.2 occ:1.00 O C:HOH716 1.6 25.4 1.0 NE2 C:HIS169 2.1 52.6 1.0 OD2 C:ASP205 2.1 35.4 1.0 NE2 C:HIS203 2.1 38.0 1.0 CD2 C:HIS169 2.7 53.1 1.0 CE1 C:HIS203 2.9 40.0 1.0 CG C:ASP205 2.9 34.1 1.0 OD1 C:ASP205 3.1 34.5 1.0 CD2 C:HIS203 3.2 38.1 1.0 CE1 C:HIS169 3.3 53.2 1.0 CB C:ALA163 3.9 41.7 1.0 CG C:HIS169 3.9 53.4 1.0 ND1 C:HIS203 4.0 39.1 1.0 CG C:HIS203 4.2 38.5 1.0 ND1 C:HIS169 4.2 53.9 1.0 CB C:ASP205 4.4 34.6 1.0

H.M.Baker, T.Proft, P.D.Webb, V.L.Arcus, J.D.Fraser, E.N.Baker. Crystallographic and Mutational Data Show That the Streptococcal Pyrogenic Exotoxin J Can Use A Common Binding Surface For T-Cell Receptor Binding and Dimerization J.Biol.Chem. V. 279 38571 2004.
ISSN: ISSN 0021-9258
PubMed: 15247241
DOI: 10.1074/JBC.M406695200