Zinc in PDB 1szc: Structural Basis For Nicotinamide Cleavage and Adp-Ribose Transfer By Nad+-Dependent SIR2 Histone/Protein Deacetylases

The structure of Structural Basis For Nicotinamide Cleavage and Adp-Ribose Transfer By Nad+-Dependent SIR2 Histone/Protein Deacetylases, PDB code: 1szc was solved by K.Zhao, R.Harshaw, X.Chai, R.Marmorstein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.89 / 1.75
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	105.267, 105.267, 66.609, 90.00, 90.00, 120.00
R / Rfree (%)	21 / 23.9

The structure of Structural Basis For Nicotinamide Cleavage and Adp-Ribose Transfer By Nad+-Dependent SIR2 Histone/Protein Deacetylases also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Structural Basis For Nicotinamide Cleavage and Adp-Ribose Transfer By Nad+-Dependent SIR2 Histone/Protein Deacetylases (pdb code 1szc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structural Basis For Nicotinamide Cleavage and Adp-Ribose Transfer By Nad+-Dependent SIR2 Histone/Protein Deacetylases, PDB code: 1szc:

Zinc binding site 1 out of 1 in the Structural Basis For Nicotinamide Cleavage and Adp-Ribose Transfer By Nad+-Dependent SIR2 Histone/Protein Deacetylases


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural Basis For Nicotinamide Cleavage and Adp-Ribose Transfer By Nad+-Dependent SIR2 Histone/Protein Deacetylases within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:30.2 occ:1.00 SG A:CYS146 2.2 32.1 1.0 SG A:CYS170 2.3 27.5 1.0 SG A:CYS173 2.3 25.4 1.0 SG A:CYS143 2.3 25.8 1.0 CB A:CYS170 3.1 24.6 1.0 CB A:CYS143 3.2 29.9 1.0 CB A:CYS146 3.2 35.9 1.0 N A:CYS146 3.4 34.8 1.0 CB A:CYS173 3.5 22.9 1.0 N A:CYS173 3.7 27.2 1.0 CA A:CYS146 3.8 33.9 1.0 CA A:CYS173 4.1 25.8 1.0 C A:GLY145 4.4 42.4 1.0 CB A:VAL172 4.5 28.1 1.0 N A:GLY147 4.5 36.6 1.0 C A:CYS146 4.5 39.8 1.0 CA A:CYS170 4.6 24.6 1.0 CA A:CYS143 4.6 29.0 1.0 C A:CYS173 4.7 29.3 1.0 N A:GLY174 4.7 24.7 1.0 CA A:GLY145 4.7 39.0 1.0 N A:LYS148 4.7 35.2 1.0 CB A:LYS148 4.8 31.9 1.0 C A:VAL172 4.8 29.0 1.0 N A:GLY145 4.8 35.5 1.0 CG1 A:VAL172 4.9 29.8 1.0 N A:GLU175 4.9 24.2 1.0

K.Zhao, R.Harshaw, X.Chai, R.Marmorstein. Structural Basis For Nicotinamide Cleavage and Adp-Ribose Transfer By Nad(+)-Dependent SIR2 Histone/Protein Deacetylases. Proc.Natl.Acad.Sci.Usa V. 101 8563 2004.
ISSN: ISSN 0027-8424
PubMed: 15150415
DOI: 10.1073/PNAS.0401057101