Zinc in PDB 1svo: Structure of SV40 Large T Antigen Helicase Domain

The structure of Structure of SV40 Large T Antigen Helicase Domain, PDB code: 1svo was solved by D.Gai, R.Zhao, C.V.Finkielstein, X.S.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.60
Space group	P 3 2 1
Cell size a, b, c (Å), α, β, γ (°)	120.444, 120.444, 131.767, 90.00, 90.00, 120.00
R / Rfree (%)	23.3 / 27.1

The binding sites of Zinc atom in the Structure of SV40 Large T Antigen Helicase Domain (pdb code 1svo). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of SV40 Large T Antigen Helicase Domain, PDB code: 1svo:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of SV40 Large T Antigen Helicase Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of SV40 Large T Antigen Helicase Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn700 b:53.1 occ:1.00 SG A:CYS305 2.0 62.6 1.0 SG A:CYS302 2.0 65.8 1.0 ND1 A:HIS317 2.1 35.0 1.0 NE2 A:HIS313 2.3 54.0 1.0 CG A:HIS317 2.9 35.5 1.0 CD2 A:HIS313 2.9 54.5 1.0 CE1 A:HIS317 3.0 32.9 1.0 CB A:HIS317 3.2 39.4 1.0 CE1 A:HIS313 3.2 54.3 1.0 CB A:CYS302 3.2 72.7 1.0 CB A:CYS305 3.7 62.6 1.0 CG A:HIS313 4.0 52.9 1.0 N A:CYS305 4.0 60.0 1.0 CD2 A:HIS317 4.0 32.4 1.0 NE2 A:HIS317 4.1 31.1 1.0 ND1 A:HIS313 4.1 54.6 1.0 CB A:LYS304 4.2 57.9 1.0 CA A:CYS305 4.3 59.2 1.0 CA A:CYS302 4.7 74.1 1.0 C A:LYS304 4.7 58.5 1.0 O A:HIS313 4.7 48.0 1.0 CA A:HIS317 4.7 42.9 1.0 CA A:LYS304 4.9 59.8 1.0 C A:HIS313 5.0 48.4 1.0

Zinc binding site 2 out of 2 in the Structure of SV40 Large T Antigen Helicase Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of SV40 Large T Antigen Helicase Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn700 b:59.4 occ:1.00 ND1 B:HIS317 1.9 44.6 1.0 SG B:CYS305 2.1 77.3 1.0 SG B:CYS302 2.2 79.0 1.0 NE2 B:HIS313 2.2 44.8 1.0 CE1 B:HIS317 2.7 43.9 1.0 CG B:HIS317 2.8 44.2 1.0 CE1 B:HIS313 2.9 45.3 1.0 CB B:HIS317 3.3 47.0 1.0 CB B:CYS302 3.3 83.2 1.0 CD2 B:HIS313 3.3 46.3 1.0 NE2 B:HIS317 3.8 43.3 1.0 CB B:CYS305 3.9 75.1 1.0 CD2 B:HIS317 3.9 42.2 1.0 ND1 B:HIS313 4.0 45.8 1.0 N B:CYS305 4.2 70.3 1.0 CG B:HIS313 4.2 45.5 1.0 CB B:LYS304 4.5 70.3 1.0 CA B:CYS305 4.6 70.8 1.0 CA B:CYS302 4.7 84.2 1.0 CB B:PHE299 4.8 71.9 1.0 CA B:HIS317 4.8 50.1 1.0 C B:LYS304 4.9 69.3 1.0 O B:GLU294 4.9 49.9 1.0 CA B:PHE299 4.9 71.4 1.0

D.Gai, R.Zhao, D.Li, C.V.Finkielstein, X.S.Chen. Mechanisms of Conformational Change For A Replicative Hexameric Helicase of SV40 Large Tumor Antigen. Cell(Cambridge,Mass.) V. 119 47 2004.
ISSN: ISSN 0092-8674
PubMed: 15454080
DOI: 10.1016/J.CELL.2004.09.017