Zinc in PDB 1r1v: Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form

The structure of Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form, PDB code: 1r1v was solved by C.Eicken, M.A.Pennella, X.Chen, K.M.Koshlap, M.L.Vanzile, J.C.Sacchettini, D.P.Giedroc, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.00 / 2.30
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	54.444, 75.370, 50.625, 90.00, 90.00, 90.00
R / Rfree (%)	19.5 / 24.9

The binding sites of Zinc atom in the Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form (pdb code 1r1v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form, PDB code: 1r1v:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:31.7 occ:1.00 OD1 A:ASP84 1.8 28.2 1.0 ND1 A:HIS86 2.0 32.6 1.0 CG A:ASP84 2.7 32.5 1.0 CE1 A:HIS86 2.9 35.4 1.0 OD2 A:ASP84 2.9 29.7 1.0 CG A:HIS86 3.0 33.1 1.0 CB A:HIS86 3.4 28.5 1.0 O A:HOH1150 3.8 60.5 1.0 NE2 A:HIS86 4.0 37.5 1.0 CB A:ASP84 4.1 28.7 1.0 CD2 A:HIS86 4.1 31.4 1.0 N A:HIS86 4.6 28.2 1.0 CA A:HIS86 4.6 26.7 1.0 OD2 A:ASP83 4.8 33.0 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:90.5 occ:1.00 NE2 A:HIS86 2.5 37.5 1.0 O A:HOH1050 2.7 46.1 1.0 CE1 A:HIS86 2.8 35.4 1.0 CD2 A:HIS86 3.8 31.4 1.0 ND1 A:HIS86 4.0 32.6 1.0 CG A:HIS86 4.6 33.1 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form within 5.0Å range:

Zinc binding site 4 out of 4 in the Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of the Metal-Sensing Transcriptional Repressor Czra From Staphylococcus Aureus in the ZN2-Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn504 b:57.3 occ:1.00 N B:SER52 3.2 30.4 1.0 N A:SER52 3.2 31.4 1.0 OD1 B:ASN55 3.3 37.0 1.0 OD1 A:ASN55 3.4 32.1 1.0 CA B:LEU51 3.6 30.6 1.0 CA A:LEU51 3.6 31.6 1.0 CB B:ASN55 3.7 36.5 1.0 OG B:SER52 3.7 24.8 1.0 CB A:ASN55 3.7 34.4 1.0 OG A:SER52 3.7 29.6 1.0 CB B:LEU51 3.8 29.6 1.0 C B:LEU51 3.9 30.9 1.0 CG B:ASN55 3.9 35.9 1.0 CD2 B:LEU51 3.9 28.0 1.0 C A:LEU51 3.9 31.9 1.0 CG A:ASN55 3.9 34.6 1.0 CD2 A:LEU51 4.0 28.2 1.0 CB A:LEU51 4.0 28.6 1.0 CB B:SER52 4.1 27.9 1.0 CB A:SER52 4.2 28.5 1.0 CA B:SER52 4.2 31.2 1.0 CA A:SER52 4.3 30.9 1.0 CG B:LEU51 4.5 28.9 1.0 CG A:LEU51 4.7 29.2 1.0 O B:SER52 4.8 33.4 1.0 O A:ASN50 4.8 35.2 1.0 N A:LEU51 4.9 33.2 1.0 O A:SER52 4.9 32.0 1.0 O B:ASN50 4.9 32.8 1.0 N B:LEU51 4.9 32.5 1.0

C.Eicken, M.A.Pennella, X.Chen, K.M.Koshlap, M.L.Vanzile, J.C.Sacchettini, D.P.Giedroc. A Metal-Ligand-Mediated Intersubunit Allosteric Switch in Related Smtb/Arsr Zinc Sensor Proteins. J.Mol.Biol. V. 333 683 2003.
ISSN: ISSN 0022-2836
PubMed: 14568530
DOI: 10.1016/J.JMB.2003.09.007