Atomistry » Zinc » PDB 1qmu-1r23 » 1qwn
Atomistry »
  Zinc »
    PDB 1qmu-1r23 »
      1qwn »

Zinc in PDB 1qwn: Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride

Enzymatic activity of Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride

All present enzymatic activity of Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride:
3.2.1.114;

Protein crystallography data

The structure of Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride, PDB code: 1qwn was solved by S.Numao, D.A.Kuntz, S.G.Withers, D.R.Rose, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.20
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 69.019, 110.019, 138.961, 90.00, 90.00, 90.00
R / Rfree (%) 17.5 / 19.2

Other elements in 1qwn:

The structure of Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride also contains other interesting chemical elements:

Fluorine (F) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride (pdb code 1qwn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride, PDB code: 1qwn:

Zinc binding site 1 out of 1 in 1qwn

Go back to Zinc Binding Sites List in 1qwn
Zinc binding site 1 out of 1 in the Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Golgi Alpha-Mannosidase II Covalent Intermediate Complex with 5- Fluoro-Gulosyl-Fluoride within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2005

b:6.5
occ:1.00
 OD1 A:ASP92 2.0 6.7 1.0
NE2 A:HIS471 2.1 5.2 1.0
NE2 A:HIS90 2.1 5.5 1.0
O3 A:GUL2003 2.1 6.6 1.0
O2 A:GUL2003 2.2 7.4 1.0
OD1 A:ASP204 2.6 6.2 1.0
CG A:ASP92 2.9 6.3 1.0
C2 A:GUL2003 2.9 7.0 1.0
CE1 A:HIS471 3.0 5.1 1.0
CD2 A:HIS90 3.1 5.2 1.0
CD2 A:HIS471 3.1 4.8 1.0
CE1 A:HIS90 3.1 5.4 1.0
C3 A:GUL2003 3.1 6.8 1.0
OD2 A:ASP92 3.2 7.9 1.0
C1 A:GUL2003 3.4 7.7 1.0
CG A:ASP204 3.6 6.2 1.0
CB A:ASP204 3.7 6.3 1.0
OD2 A:ASP472 4.0 5.7 1.0
C4 A:GUL2003 4.1 7.6 1.0
ND1 A:HIS471 4.2 5.3 1.0
ND1 A:HIS90 4.2 6.1 1.0
CG A:HIS90 4.2 5.6 1.0
CG A:HIS471 4.2 4.5 1.0
CE1 A:HIS470 4.3 5.6 1.0
CB A:ASP92 4.3 6.2 1.0
O A:HOH2097 4.5 7.8 1.0
O A:GUL2003 4.6 7.6 1.0
OD2 A:ASP204 4.7 6.8 1.0
CA A:ASP92 4.8 5.4 1.0
OH A:TYR269 4.9 8.8 1.0
NE2 A:HIS470 4.9 5.2 1.0

Reference:

S.Numao, D.A.Kuntz, S.G.Withers, D.R.Rose. Insights Into the Mechanism of Drosophila Melanogaster Golgi Alpha-Mannosidase II Through the Structural Analysis of Covalent Reaction Intermediates. J.Biol.Chem. V. 278 48074 2003.
ISSN: ISSN 0021-9258
PubMed: 12960159
DOI: 10.1074/JBC.M309249200
Page generated: Wed Oct 16 18:17:26 2024

Last articles

As in 2VQL
As in 2WA7
As in 2VW8
As in 2VS0
As in 2VQK
As in 2V98
As in 2V97
As in 2VQH
As in 2VDL
As in 2VEQ
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy