Atomistry » Zinc » PDB 1lg5-1m2j » 1lnd
Atomistry »
  Zinc »
    PDB 1lg5-1m2j »
      1lnd »

Zinc in PDB 1lnd: A Structural Analysis of Metal Substitutions in Thermolysin

Enzymatic activity of A Structural Analysis of Metal Substitutions in Thermolysin

All present enzymatic activity of A Structural Analysis of Metal Substitutions in Thermolysin:
3.4.24.27;

Protein crystallography data

The structure of A Structural Analysis of Metal Substitutions in Thermolysin, PDB code: 1lnd was solved by D.R.Holland, A.C.Hausrath, D.Juers, B.W.Matthews, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.70
Space group P 61 2 2
Cell size a, b, c (Å), α, β, γ (°) 93.852, 93.852, 131.322, 90.00, 90.00, 120.00
R / Rfree (%) n/a / n/a

Other elements in 1lnd:

The structure of A Structural Analysis of Metal Substitutions in Thermolysin also contains other interesting chemical elements:

Calcium (Ca) 4 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the A Structural Analysis of Metal Substitutions in Thermolysin (pdb code 1lnd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the A Structural Analysis of Metal Substitutions in Thermolysin, PDB code: 1lnd:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 1lnd

Go back to Zinc Binding Sites List in 1lnd
Zinc binding site 1 out of 2 in the A Structural Analysis of Metal Substitutions in Thermolysin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of A Structural Analysis of Metal Substitutions in Thermolysin within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn800

b:14.9
occ:1.00
O E:HOH910 1.8 21.4 1.0
NE2 E:HIS142 1.9 14.1 1.0
NE2 E:HIS146 2.0 10.5 1.0
OE1 E:GLU166 2.1 18.8 1.0
OE2 E:GLU166 2.7 33.0 1.0
CD E:GLU166 2.7 14.3 1.0
CE1 E:HIS142 2.9 17.1 1.0
CE1 E:HIS146 3.0 17.4 1.0
CD2 E:HIS142 3.0 20.2 1.0
CD2 E:HIS146 3.0 15.5 1.0
ZN E:ZN801 3.2 30.6 0.5
OE2 E:GLU143 3.6 16.3 0.5
ND1 E:HIS142 4.1 10.6 1.0
CG E:HIS142 4.1 10.5 1.0
ND1 E:HIS146 4.1 15.6 1.0
CG E:HIS146 4.1 12.0 1.0
CG E:GLU166 4.2 11.9 1.0
OH E:TYR157 4.2 46.9 1.0
NE2 E:HIS231 4.2 26.0 1.0
O E:HOH1058 4.2 37.9 1.0
CA E:VAL1321 4.3 47.1 1.0
CD E:GLU143 4.4 81.5 0.5
OE1 E:GLU143 4.4 12.7 0.5
OE1 E:GLU143 4.4 8.4 0.5
CB E:SER169 4.5 9.8 1.0
O E:VAL1321 4.7 32.5 1.0
C E:VAL1321 4.7 78.5 1.0
OG E:SER169 4.7 11.7 1.0
N E:VAL1321 4.7 37.9 1.0
CA E:GLU166 4.7 13.5 1.0
CD2 E:HIS231 4.8 30.0 1.0
CB E:GLU166 4.8 13.6 1.0
CE1 E:TYR157 4.9 0.0 1.0
CZ E:TYR157 5.0 0.0 1.0

Zinc binding site 2 out of 2 in 1lnd

Go back to Zinc Binding Sites List in 1lnd
Zinc binding site 2 out of 2 in the A Structural Analysis of Metal Substitutions in Thermolysin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of A Structural Analysis of Metal Substitutions in Thermolysin within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn801

b:30.6
occ:0.50
OH E:TYR157 1.8 46.9 1.0
O E:HOH910 2.0 21.4 1.0
NE2 E:HIS231 2.3 26.0 1.0
OE2 E:GLU166 2.6 33.0 1.0
CE1 E:HIS231 2.7 20.0 1.0
CZ E:TYR157 3.1 0.0 1.0
ZN E:ZN800 3.2 14.9 1.0
CD E:GLU166 3.4 14.3 1.0
CD2 E:HIS231 3.6 30.0 1.0
OE1 E:GLU166 3.6 18.8 1.0
CE1 E:TYR157 3.8 0.0 1.0
ND1 E:HIS231 4.0 32.6 1.0
O E:HOH1058 4.1 37.9 1.0
CE2 E:TYR157 4.2 0.0 1.0
N E:LYS1322 4.3 61.1 1.0
C E:VAL1321 4.3 78.5 1.0
N E:VAL1321 4.3 37.9 1.0
NE2 E:HIS146 4.4 10.5 1.0
CG E:HIS231 4.4 21.6 1.0
O E:LYS1322 4.4 52.8 1.0
CG E:GLU166 4.5 11.9 1.0
CA E:VAL1321 4.5 47.1 1.0
O E:VAL1321 4.6 32.5 1.0
CA E:LYS1322 4.8 76.2 1.0
NE2 E:HIS142 4.8 14.1 1.0
C E:LYS1322 4.9 0.0 1.0
OE2 E:GLU143 5.0 16.3 0.5

Reference:

D.R.Holland, A.C.Hausrath, D.Juers, B.W.Matthews. Structural Analysis of Zinc Substitutions in the Active Site of Thermolysin. Protein Sci. V. 4 1955 1995.
ISSN: ISSN 0961-8368
PubMed: 8535232
Page generated: Wed Dec 16 02:56:23 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy